Zeekoevlei is a major freshwater lake on the Cape Flats near Cape Town, Western Cape Province, South Africa.  The name means "hippopotamus marsh," with "vlei" being Afrikaans for "marsh", and "zeekoe" (i.e. "sea-cow") being Afrikaans for hippopotamus.
Zeekoevlei Nature Reserve (established in June 2000) is based on the lake. It is separated by a peninsula from the Rondevlei Nature Reserve and preserves endangered Cape Lowland Freshwater Wetland ecosystems. 
- Biodiversity of Cape Town
- List of nature reserves in Cape Town
- Cape Lowland Freshwater Wetland