Zolantidine

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Zolantidine
Zolantidine.svg
Clinical data
ATC code
  • None
Identifiers
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
Chemical and physical data
FormulaC22H27N3OS
Molar mass381.5 g/mol g·mol−1
3D model (JSmol)

Zolantidine is a brain-penetrating selective histamine H2 receptor (HRH2) antagonist developed by Smith, Kline & French, with the research code of SK&F 95282. It is a benzthiazole derivative with a 30-fold higher potency for H2 receptors than other peripheral and central receptors.[1]

References[edit]

  1. ^ Calcutt, CR; Ganellin, CR; Griffiths, R; Leigh, BK; Maguire, JP; Mitchell, RC; Mylek, ME; Parsons, ME; Smith, IR; Young, RC (January 1988). "Zolantidine (SK&F 95282) is a Potent Selective Brain-penetrating Histamine H2-receptor Antagonist". British Journal of Pharmacology. 93 (1): 69–78. doi:10.1111/j.1476-5381.1988.tb11406.x. PMC 1853786. PMID 2894879.