OR1E1

OR1E1
Identifiers
Aliases	OR1E1, HGM071, OR13-66, OR17-2, OR17-32, OR1E5, OR1E6, OR1E8P, OR1E9P, OST547, olfactory receptor family 1 subfamily E member 1
External IDs	MGI: 3030231; HomoloGene: 74111; GeneCards: OR1E1; OMA:OR1E1 - orthologs
Gene location (Human) Chr. Chromosome 17 (human) Band 17p13.3 Start 3,397,104 bp End 3,398,410 bp
Gene location (Mouse) Chr. Chromosome 11 (mouse) Band 11|11 B4 Start 73,851,643 bp End 73,858,638 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in muscle of thigh gastrocnemius muscle placenta mammary gland breast lactiferous gland prefrontal cortex temporal lobe tibial nerve sigmoid colon n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity transmembrane signaling receptor activity signal transducer activity olfactory receptor activity Cellular component membrane plasma membrane integral component of membrane Biological process detection of chemical stimulus involved in sensory perception signal transduction response to stimulus sensory perception of smell detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 8387 258343 Ensembl ENSG00000180016 ENSMUSG00000057050 UniProt P30953 Q8VEZ6 RefSeq (mRNA) NM_003553 NM_146346 RefSeq (protein) NP_003544 NP_666458 Location (UCSC) Chr 17: 3.4 – 3.4 Mb Chr 11: 73.85 – 73.86 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Olfactory receptor 1E1 is a protein that in humans is encoded by the OR1E1 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Rouquier S, Taviaux S, Trask BJ, et al. (1998). "Distribution of olfactory receptor genes in the human genome". Nat. Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546. S2CID 31129045.
• Glusman G, Sosinsky A, Ben-Asher E, et al. (2000). "Sequence, structure, and evolution of a complete human olfactory receptor gene cluster". Genomics. 63 (2): 227–45. doi:10.1006/geno.1999.6030. PMID 10673334. S2CID 23416814.
• Rouquier S, Blancher A, Giorgi D (2000). "The olfactory receptor gene repertoire in primates and mouse: evidence for reduction of the functional fraction in primates". Proc. Natl. Acad. Sci. U.S.A. 97 (6): 2870–4. Bibcode:2000PNAS...97.2870R. doi:10.1073/pnas.040580197. PMC 16022. PMID 10706615.
• Fuchs T, Malecova B, Linhart C, et al. (2003). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR1E1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.