TAS2R19

TAS2R19
Identifiers
Aliases	TAS2R19, MSTP058, T2R19, T2R23, T2R48, TAS2R23, TAS2R48, taste 2 receptor member 19
External IDs	OMIM: 613961 MGI: 2681304 HomoloGene: 89250 GeneCards: TAS2R19
Gene location (Human) Chr. Chromosome 12 (human) Band 12p13.2 Start 11,021,619 bp End 11,022,620 bp
Gene location (Mouse) Chr. Chromosome 6 (mouse) Band 6 G1|6 64.03 cM Start 132,754,142 bp End 132,755,125 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum Achilles tendon thymus cerebellar cortex cerebellar hemisphere stromal cell of endometrium gastrocnemius muscle ganglionic eminence skeletal muscle tissue tibial nerve n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity signal transducer activity bitter taste receptor activity Cellular component integral component of membrane plasma membrane membrane Biological process detection of chemical stimulus involved in sensory perception of bitter taste signal transduction response to stimulus sensory perception of taste G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 259294 353165 Ensembl ENSG00000212124 ENSMUSG00000053217 UniProt P59542 Q7TQA8 RefSeq (mRNA) NM_176888 NM_181276 RefSeq (protein) NP_795369 NP_851793 Location (UCSC) Chr 12: 11.02 – 11.02 Mb Chr 6: 132.75 – 132.76 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

Taste receptor type 2 member 19 is a protein that in humans is encoded by the TAS2R19 gene. It seems to be involved in the perception of salt and bitter tastes.

See also

• Taste receptor

Further reading

• Margolskee RF (2002). "Molecular mechanisms of bitter and sweet taste transduction". J. Biol. Chem. 277 (1): 1–4. doi:10.1074/jbc.R100054200. PMID 11696554.
• Montmayeur JP, Matsunami H (2002). "Receptors for bitter and sweet taste". Curr. Opin. Neurobiol. 12 (4): 366–71. doi:10.1016/S0959-4388(02)00345-8. PMID 12139982. S2CID 37807140.
• Bufe B, Hofmann T, Krautwurst D, Raguse JD, Meyerhof W (2002). "The human TAS2R16 receptor mediates bitter taste in response to beta-glucopyranosides". Nat. Genet. 32 (3): 397–401. doi:10.1038/ng1014. PMID 12379855. S2CID 20426192.
• Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba NJ (2003). "Coding of sweet, bitter, and umami tastes: different receptor cells sharing similar signaling pathways". Cell. 112 (3): 293–301. doi:10.1016/S0092-8674(03)00071-0. PMID 12581520. S2CID 718601.
• Fischer A, Gilad Y, Man O, Pääbo S (2005). "Evolution of bitter taste receptors in humans and apes". Mol. Biol. Evol. 22 (3): 432–6. doi:10.1093/molbev/msi027. PMID 15496549.
• Go Y, Satta Y, Takenaka O, Takahata N (2006). "Lineage-specific loss of function of bitter taste receptor genes in humans and nonhuman primates". Genetics. 170 (1): 313–26. doi:10.1534/genetics.104.037523. PMC 1449719. PMID 15744053.
• Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, Mann M (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.