Jump to content

Rugulosin: Difference between revisions

From Wikipedia, the free encyclopedia
Content deleted Content added
Created page with '{{Chembox <!-- Images --> | ImageFile = | ImageSize = | ImageAlt = <!-- Names --> | IUPACName = 8,10,14,23,25,28-hexahydroxy-6,21-dimethy...'
(No difference)

Revision as of 06:49, 6 May 2021

Rugulosin
Names
IUPAC name
8,10,14,23,25,28-hexahydroxy-6,21-dimethyloctacyclo[14.11.1.02,11.02,15.04,9.013,17.017,26.019,24]octacosa-4(9),5,7,10,19(24),20,22,25-octaene-3,12,18,27-tetrone
Identifiers
ChemSpider
  • Key: QFDPVUTXKUGISP-UHFFFAOYSA-N
Properties
C30H22O10
Molar mass 542.496 g·mol−1
Melting point 290°C
Boiling point 1009.4±65.0°C at 760 mmHg
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Rugulosin is an anthraquinoid mycotoxin with the molecular formula C30H22O10 which is produced by penicillium species.[1][2][3] Rugulosin is hepatotoxic and is cancerogenic.[4]

References

  1. ^ "Rugulosin". pubchem.ncbi.nlm.nih.gov.
  2. ^ Ueno, Yoshio; Sato, Norio; Ito, Teruo; Ueno, Ikuko; Enomoto, Makoto; Tsunoda, Hiroshi (1980). "CHRONIC TOXICITY AND HEPATOCARCINOGENICITY OF (+) RUGULOSIN, AN ANTHRAQUINOID MYCOTOXIN FROM PENICILLIUM SPECIES : PRELIMINARY SURVEYS IN MICE". The Journal of Toxicological Sciences. 5 (4): 295–302. doi:10.2131/jts.5.295.
  3. ^ Ueno, Y; Ueno, I; Sato, N; Iitoi, Y; Saito, M (June 1971). "Toxicological approach to (+) rugulosin, an anthraquinoid mycotoxin of Penicillium rugulosum Thom". The Japanese journal of experimental medicine. 41 (3): 177–88. PMID 5314585.
  4. ^ Eisenbrand, Gerhard; Schreier, Peter. RÖMPP Lexikon Lebensmittelchemie, 2. Auflage, 2006 (in German). Georg Thieme Verlag. ISBN 978-3-13-179532-8.

Further reading

  • Eckardt, Christiane. Mykotoxine in Lebensmitteln (in German). Fischer. p. 23. ISBN 978-3-437-10650-7.
  • Studies in Natural Products Chemistry. Elsevier. ISBN 978-0-444-63469-6.
  • Steyn, Pieter. The Biosynthesis of Mycotoxins: A study in secondary Metabolism. Elsevier. p. 375. ISBN 978-0-323-14993-8.
  • Pirttilä, Anna Maria; Frank, A. Carolin. Endophytes of Forest Trees: Biology and Applications. Springer Science & Business Media. p. 244. ISBN 978-94-007-1599-8.