Luteoskyrin: Difference between revisions

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Luteoskyrin
Names
IUPAC name
5,8,10,14,20,23,25,28-octahydroxy-6,21-dimethyloctacyclo[14.11.1.02,11.02,15.04,9.013,17.017,26.019,24]octacosa-4,6,8,10,19,21,23,25-octaene-3,12,18,27-tetrone
Identifiers
  • Key: FAZDYVMEXQHRLI-UHFFFAOYSA-N
Properties
C30H22O12
Molar mass 574.494 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Luteoskyrin is a hepatotoxic and hepatocarcinogenic mycotoxin with the molecular formula C30H22O12 which is produced by the mold Penicillium islandicum[1][2][3][4] Luteoskyrin has strong cytotoxic effects.[5][6] Luteoskyrin can cause the Yellow Rice Disease.[1]

References

  1. ^ a b Weidenbörner, Martin. Lexikon der Lebensmittelmykologie (in German). Springer-Verlag. p. 82. ISBN 978-3-642-57058-2.
  2. ^ Hänsel, Rudolf; Keller, Konstantin; Rimpler, Horst; Schneider, Georg. Hagers Handbuch der Pharmazeutischen Praxis: Drogen P-Z Folgeband 2 (in German). Springer-Verlag. ISBN 978-3-642-57881-6.
  3. ^ Eisenbrand, Gerhard; Schreier, Peter. RÖMPP Lexikon Lebensmittelchemie, 2. Auflage, 2006 (in German). Georg Thieme Verlag. p. 41. ISBN 978-3-13-179532-8.
  4. ^ Ueno, Yoshio; Ishikawa, Ichijiro (September 1969). "Production of Luteoskyrin, a Hepatotoxic Pigment, by Penicillium islandicum Sopp". Applied Microbiology. 18 (3): 406–409. ISSN 0003-6919.
  5. ^ Keutel, J.; Möckel, H. (1 December 1969). "Induction of chromosomal breakage in cultured human leucocytes by luteoskyrin". Humangenetik. 7 (4): 344–348. doi:10.1007/BF00283556. ISSN 1432-1203.
  6. ^ Möckel, Horst. Chromosomenaberrationen an kultivierten menschlichen leukozyten (in German). Marburg. p. 39.

Further reading

  • Ueno, I.; Hoshino, M.; Maitani, T.; Kanegasaki, S.; Ueno, Y. (1 October 1993). "Luteoskyrin, an Anthraquinoid Hepatotoxin, and Ascorbic Acid Generate Hydroxyl Radical in vitro in the Presence of a Trace Amount of Ferrous Iron". Free Radical Research Communications. 19 (sup1): s95–s100. doi:10.3109/10715769309056s95. ISSN 8755-0199.
  • Okuto, Hiroshi; Sasada, Yoshio; Sakurai, Kiichi (February 1958). "X-ray Determination of the Molecular Weight of Luteoskyrin". Bulletin of the Chemical Society of Japan. 31 (2): 247–248. doi:10.1246/bcsj.31.247.
  • UENO, YOSHIO; UENO, IKUKO; MIZUMOTO, KIYOHISA; TATSUNO, TAKASHI (1 March 1968). "The Binding of Luteoskyrin, a Hepatotoxic Pigment of Penicillium islandicum Sopp, to Deoxyribonucleohistone*". The Journal of Biochemistry. 63 (3): 395–397. doi:10.1093/oxfordjournals.jbchem.a128787. ISSN 0021-924X.
  • Jr, Busby W. F.; G.n, Wogan (1981). "Luteoskyrin [Pharmacokinetics, effects on mitochondrial function, DNA complex formation, inhibition of macromolecular synthesis, mycotoxins, Penicillium islandicum]". {{cite journal}}: Cite journal requires |journal= (help)