Occupational cardiovascular disease: Difference between revisions

From Wikipedia, the free encyclopedia
Content deleted Content added
Tshockey (talk | contribs)
combined headings on risk-factors (non-chemical and chemical) to work-related risk factors; added to the list of risk factors and provided citations
Tshockey (talk | contribs)
added entire section with citations - "United States trends in cardiovascular disease deaths and the impact of work"
Line 24: Line 24:
| deaths =
| deaths =
}}
}}
'''Occupational cardiovascular diseases''' are diseases of the [[heart]] or [[blood vessel]]s caused by working conditions, making them a form of [[Occupational disease|occupational illness]]. These diseases include [[Coronary artery disease|coronary heart disease]], [[stroke]], [[cardiomyopathy]], [[Arrhythmia|arrythmia]], and [[heart valve]] or heart chamber problems. [[Cardiovascular disease]] is the leading cause of death in the United States and worldwide.<ref>{{Cite journal |date=2021-07-01 |title=National vital statistics report ; v. 70, no. 9 |url=https://doi.org/10.15620/cdc:107021 |language=en |doi=10.15620/cdc:107021}}</ref><ref>{{Cite web |title=The top 10 causes of death |url=https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death |access-date=2023-02-08 |website=www.who.int |language=en}}</ref> In the United States, cardiovascular diseases account for one out of four deaths.<ref name="pmid30700139">{{cite journal | vauthors = Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, etal | collaboration = American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee | title = Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association | journal = Circulation | volume = 139 | issue = 10 | pages = e56–e528 | date = March 2019 | pmid = 30700139 | doi = 10.1161/CIR.0000000000000659 | doi-access = free }}</ref>
'''Occupational cardiovascular diseases''' are diseases of the [[heart]] or [[blood vessel]]s caused by working conditions, making them a form of [[Occupational disease|occupational illness]]. These diseases include [[Coronary artery disease|coronary heart disease]], [[stroke]], [[cardiomyopathy]], [[Arrhythmia|arrythmia]], and [[heart valve]] or heart chamber problems. [[Cardiovascular disease]] is the leading cause of death in the United States and worldwide.<ref>{{Cite journal |date=2021-07-01 |title=National vital statistics report ; v. 70, no. 9 |url=https://doi.org/10.15620/cdc:107021 |language=en |doi=10.15620/cdc:107021}}</ref><ref>{{Cite web |title=The top 10 causes of death |url=https://www.who.int/news-room/fact-sheets/detail/the-top-10-causes-of-death |access-date=2023-02-08 |website=www.who.int |language=en}}</ref> In the United States, cardiovascular diseases account for one out of four deaths.<ref name="pmid30700139">{{cite journal | vauthors = Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, etal | collaboration = American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee | title = Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association | journal = Circulation | volume = 139 | issue = 10 | pages = e56–e528 | date = March 2019 | pmid = 30700139 | doi = 10.1161/CIR.0000000000000659 | doi-access = free }}</ref> The 6th International Conference on Work Environment and Cardiovascular Diseases found that within the working age population about 10-20% of cardiovascular disease deaths can be attributed to work.<ref>{{Cite journal |last=Tsutsumi |first=Akizumi |date=2015 |title=Prevention and management of work-related cardiovascular disorders |url=https://pubmed.ncbi.nlm.nih.gov/26159941 |journal=International Journal of Occupational Medicine and Environmental Health |volume=28 |issue=1 |pages=4–7 |doi=10.2478/s13382-014-0319-z |issn=1896-494X |pmid=26159941}}</ref> Ten workplace stressors (shift work, job insecurity, high job demand, etc.) were estimated to be associated with 120,000 U.S. deaths each year and account for 5-8% of health care costs.<ref>{{Cite journal |last=Goh |first=Joel |last2=Pfeffer |first2=Jeffrey |last3=Zenios |first3=Stefanos A. |date=2016-02 |title=The Relationship Between Workplace Stressors and Mortality and Health Costs in the United States |url=http://pubsonline.informs.org/doi/10.1287/mnsc.2014.2115 |journal=Management Science |language=en |volume=62 |issue=2 |pages=608–628 |doi=10.1287/mnsc.2014.2115 |issn=0025-1909}}</ref>


Research related to the association between work and cardiovascular disease is on-going. Links have been established between cardiovascular disease risk and occupational exposure to chemicals, noise, psychosocial stressors, physical activity, and certain workplace organization factors. Additionally, work-related risk factors for cardiovascular disease may also increase the risk of other cardiovascular disease risk factors such as [[hypertension]]<ref>{{Cite journal |last=Bolm-Audorff |first=Ulrich |last2=Hegewald |first2=Janice |last3=Pretzsch |first3=Anna |last4=Freiberg |first4=Alice |last5=Nienhaus |first5=Albert |last6=Seidler |first6=Andreas |date=2020-01 |title=Occupational Noise and Hypertension Risk: A Systematic Review and Meta-Analysis |url=https://www.mdpi.com/1660-4601/17/17/6281 |journal=International Journal of Environmental Research and Public Health |language=en |volume=17 |issue=17 |pages=6281 |doi=10.3390/ijerph17176281 |issn=1660-4601 |pmc=PMC7504405 |pmid=32872306}}</ref><ref>{{Cite journal |last=Teixeira |first=Liliane R. |last2=Pega |first2=Frank |last3=Dzhambov |first3=Angel M. |last4=Bortkiewicz |first4=Alicja |last5=da Silva |first5=Denise T. Correa |last6=de Andrade |first6=Carlos A. F. |last7=Gadzicka |first7=Elzbieta |last8=Hadkhale |first8=Kishor |last9=Iavicoli |first9=Sergio |last10=Martínez-Silveira |first10=Martha S. |last11=Pawlaczyk-Łuszczyńska |first11=Małgorzata |last12=Rondinone |first12=Bruna M. |last13=Siedlecka |first13=Jadwiga |last14=Valenti |first14=Antonio |last15=Gagliardi |first15=Diana |date=2021-09-01 |title=The effect of occupational exposure to noise on ischaemic heart disease, stroke and hypertension: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-Related Burden of Disease and Injury |url=https://www.sciencedirect.com/science/article/pii/S0160412021000118 |journal=Environment International |language=en |volume=154 |pages=106387 |doi=10.1016/j.envint.2021.106387 |issn=0160-4120 |pmc=PMC8204276 |pmid=33612311}}</ref>, [[diabetes]]<ref>{{Cite journal |last=Cosgrove |first=M. P. |last2=Sargeant |first2=L. A. |last3=Caleyachetty |first3=R. |last4=Griffin |first4=S. J. |date=2012-02-14 |title=Work-related stress and Type 2 diabetes: systematic review and meta-analysis |url=https://doi.org/10.1093/occmed/kqs002 |journal=Occupational Medicine |volume=62 |issue=3 |pages=167–173 |doi=10.1093/occmed/kqs002 |issn=0962-7480}}</ref><ref>{{Cite journal |last=Sui |first=Hua |last2=Sun |first2=Nijing |last3=Zhan |first3=Libin |last4=Lu |first4=Xiaoguang |last5=Chen |first5=Tuo |last6=Mao |first6=Xinyong |date=2016-08-11 |title=Association between Work-Related Stress and Risk for Type 2 Diabetes: A Systematic Review and Meta-Analysis of Prospective Cohort Studies |url=https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0159978 |journal=PLOS ONE |language=en |volume=11 |issue=8 |pages=e0159978 |doi=10.1371/journal.pone.0159978 |issn=1932-6203 |pmc=PMC4981307 |pmid=27513574}}</ref><ref>{{Cite journal |last=Krajnak |first=Kristine M. |date=2014-01 |title=Potential Contribution of Work-Related Psychosocial Stress to the Development of Cardiovascular Disease and Type II Diabetes: A Brief Review |url=http://journals.sagepub.com/doi/10.4137/EHI.S15263 |journal=Environmental Health Insights |language=en |volume=8s1 |pages=EHI.S15263 |doi=10.4137/EHI.S15263 |issn=1178-6302 |pmc=PMC4251185 |pmid=25525370}}</ref>, [[obesity]]<ref>{{Cite journal |last=Geda |first=Nigatu Regassa |last2=Feng |first2=Cindy Xin |last3=Yu |first3=Yamei |date=2022-03-29 |title=Examining the association between work stress, life stress and obesity among working adult population in Canada: findings from a nationally representative data |url=https://doi.org/10.1186/s13690-022-00865-8 |journal=Archives of Public Health |language=en |volume=80 |issue=1 |pages=97 |doi=10.1186/s13690-022-00865-8 |issn=2049-3258 |pmc=PMC8966340 |pmid=35351179}}</ref><ref name=":7">{{Cite journal |last=van den Berge |first=Mandy |last2=van der Beek |first2=Allard J. |last3=Türkeli |first3=Rukiye |last4=van Kalken |first4=Marike |last5=Hulsegge |first5=Gerben |date=2021-05-01 |title=Work-related physical and psychosocial risk factors cluster with obesity, smoking and physical inactivity |url=https://doi.org/10.1007/s00420-020-01627-1 |journal=International Archives of Occupational and Environmental Health |language=en |volume=94 |issue=4 |pages=741–750 |doi=10.1007/s00420-020-01627-1 |issn=1432-1246 |pmc=PMC8068657 |pmid=33409697}}</ref>, unhealthy diet<ref>{{Cite web |title=The effect of shift work on eating habits on JSTOR |url=https://www.jstor.org/stable/26567055 |access-date=2023-02-08 |website=www.jstor.org |language=en}}</ref>, leisure-time physical inactivity<ref name=":7" />, and [[Alcohol abuse|excessive alcohol use]]<ref>{{Cite journal |last=Frone |first=M. R. |date=1999 |title=Work stress and alcohol use |url=https://pubmed.ncbi.nlm.nih.gov/10890825 |journal=Alcohol Research & Health: The Journal of the National Institute on Alcohol Abuse and Alcoholism |volume=23 |issue=4 |pages=284–291 |issn=1535-7414 |pmc=6760381 |pmid=10890825}}</ref>. Work may also increase risk of [[Depression (mood)|depression]]<ref>{{Cite journal |last=Rugulies |first=Reiner |last2=Sørensen |first2=Kathrine |last3=Di Tecco |first3=Cristina |last4=Bonafede |first4=Michela |last5=Rondinone |first5=Bruna M. |last6=Ahn |first6=Seoyeon |last7=Ando |first7=Emiko |last8=Ayuso-Mateos |first8=Jose Luis |last9=Cabello |first9=Maria |last10=Descatha |first10=Alexis |last11=Dragano |first11=Nico |last12=Durand-Moreau |first12=Quentin |last13=Eguchi |first13=Hisashi |last14=Gao |first14=Junling |last15=Godderis |first15=Lode |date=2021-10-01 |title=The effect of exposure to long working hours on depression: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury |url=https://www.sciencedirect.com/science/article/pii/S0160412021002543 |journal=Environment International |language=en |volume=155 |pages=106629 |doi=10.1016/j.envint.2021.106629 |issn=0160-4120}}</ref>, burnout<ref>{{Cite journal |last=Salvagioni |first=Denise Albieri Jodas |last2=Melanda |first2=Francine Nesello |last3=Mesas |first3=Arthur Eumann |last4=González |first4=Alberto Durán |last5=Gabani |first5=Flávia Lopes |last6=Andrade |first6=Selma Maffei de |date=2017-10-04 |title=Physical, psychological and occupational consequences of job burnout: A systematic review of prospective studies |url=https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0185781 |journal=PLOS ONE |language=en |volume=12 |issue=10 |pages=e0185781 |doi=10.1371/journal.pone.0185781 |issn=1932-6203 |pmc=PMC5627926 |pmid=28977041}}</ref>, sleeping problems<ref>{{Cite journal |last=Litwiller |first=Brett |last2=Snyder |first2=Lori Anderson |last3=Taylor |first3=William D. |last4=Steele |first4=Logan M. |date=2017-04 |title=The relationship between sleep and work: A meta-analysis. |url=http://doi.apa.org/getdoi.cfm?doi=10.1037/apl0000169 |journal=Journal of Applied Psychology |language=en |volume=102 |issue=4 |pages=682–699 |doi=10.1037/apl0000169 |issn=1939-1854}}</ref>, and physiological and cardiorespiratory stress mechanisms in the body which may also affect the risk for cardiovascular disease.
Little is known about occupational risks for heart disease, but links have been established between cardiovascular disease and certain toxins (including [[carbon disulfide]], [[nitroglycerin]], and [[carbon monoxide]]), extreme heat and cold, exposure to [[tobacco]] smoke, ultrafine particles, [[Depression (mood)|depression]], and [[occupational stress]]. Other [[occupational hazard]]s potentially related to cardiovascular disease include [[Industrial noise|noise exposure at work]], [[shift work]], and physical activity at work.<ref>{{Cite web|url=https://www.cdc.gov/niosh/programs/crcd/|title=CDC - NIOSH Program Portfolio : Cancer, Reproductive, and Cardiovascular Diseases: Program Description| work = The National Institute for Occupational Safety and Health (NIOSH) and the Centers for Disease Control and Prevention | publisher = U.S. Department of Health & Human Services |access-date=2016-04-21}}</ref>

==United States trends in cardiovascular disease and the impact of work==
Age-adjusted cardiovascular disease death rates in the U.S. are no longer declining, as they previously had been since the 1960s.<ref name=":8">{{Cite journal |last=Woolf |first=Steven H. |last2=Schoomaker |first2=Heidi |date=2019-11-26 |title=Life Expectancy and Mortality Rates in the United States, 1959-2017 |url=https://pubmed.ncbi.nlm.nih.gov/31769830 |journal=JAMA |volume=322 |issue=20 |pages=1996–2016 |doi=10.1001/jama.2019.16932 |issn=1538-3598 |pmc=7146991 |pmid=31769830}}</ref> Cardiovascular disease death rates are increasing in older (45-64 years) working-age people.<ref>{{Cite web |title=Trends in cancer and heart disease death rates among adults aged 45–64: United States, 1999–2017 |url=https://stacks.cdc.gov/view/cdc/78673 |access-date=2023-02-08 |website=stacks.cdc.gov}}</ref> In fact, death rates from all causes have been increasing since about 2012 in working-age people (25-64 years), primarily due to increases in drug (mainly opioid) overdoses, alcohol abuse, suicides, and chronic diseases, such as cardiovascular diseases, hypertension and diabetes.<ref name=":8" /> Between 2000-2015, the cardiovascular disease mortality gap between the U.S. and other wealthy countries has widened.<ref>{{Cite web |url=https://www.nationalacademies.org/ocga/testimony-before-congress/high-and-rising-mortality-rates-among-working-age-adults |access-date=2023-02-08 |website=www.nationalacademies.org}}</ref> These trends are occurring despite improvements in the medical treatment of cardiovascular diseases. Primary prevention of cardiovascular diseases, including workplace health promotion, is key to reducing death rates.

Related explanations for cardiovascular disease trends are increases in the prevalence of other stress-related (including work-related stress) conditions, obesity<ref name=":9">{{Cite journal |last=Tsao |first=Connie W. |last2=Aday |first2=Aaron W. |last3=Almarzooq |first3=Zaid I. |last4=Alonso |first4=Alvaro |last5=Beaton |first5=Andrea Z. |last6=Bittencourt |first6=Marcio S. |last7=Boehme |first7=Amelia K. |last8=Buxton |first8=Alfred E. |last9=Carson |first9=April P. |last10=Commodore-Mensah |first10=Yvonne |last11=Elkind |first11=Mitchell S.V. |last12=Evenson |first12=Kelly R. |last13=Eze-Nliam |first13=Chete |last14=Ferguson |first14=Jane F. |last15=Generoso |first15=Giuliano |date=2022-02-22 |title=Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association |url=https://www.ahajournals.org/doi/10.1161/CIR.0000000000001052 |journal=Circulation |language=en |volume=145 |issue=8 |doi=10.1161/CIR.0000000000001052 |issn=0009-7322}}</ref>, diabetes<ref name=":9" />, metabolic syndrome<ref name=":9" />, and short sleeping hours<ref>{{Cite journal |last=Sheehan |first=Connor M. |last2=Frochen |first2=Stephen E. |last3=Walsemann |first3=Katrina M. |last4=Ailshire |first4=Jennifer A. |date=2019-02-01 |title=Are U.S. adults reporting less sleep?: Findings from sleep duration trends in the National Health Interview Survey, 2004-2017 |url=https://pubmed.ncbi.nlm.nih.gov/30452725 |journal=Sleep |volume=42 |issue=2 |pages=zsy221 |doi=10.1093/sleep/zsy221 |issn=1550-9109 |pmc=6941709 |pmid=30452725}}</ref>. The age-adjusted prevalence of hypertension increased in the U.S. between 1988-2010 and increased again between 2010-2018 for most gender-race groups<ref name=":9" />. Mental health disorders, including depression and anxiety, are increasing globally and in the U.S.<ref>{{Cite journal |last=World Health Organization |date=2017 |title=Depression and other common mental disorders: global health estimates |url=https://apps.who.int/iris/handle/10665/254610 |language=en}}</ref><ref>{{Cite journal |last=Olfson |first=Mark |last2=Wang |first2=Shuai |last3=Wall |first3=Melanie |last4=Marcus |first4=Steven C. |last5=Blanco |first5=Carlos |date=2019-02-01 |title=Trends in Serious Psychological Distress and Outpatient Mental Health Care of US Adults |url=https://pubmed.ncbi.nlm.nih.gov/30484838 |journal=JAMA psychiatry |volume=76 |issue=2 |pages=152–161 |doi=10.1001/jamapsychiatry.2018.3550 |issn=2168-6238 |pmc=6439744 |pmid=30484838}}</ref>

A 2021 National Academy of Sciences report<ref>{{Cite journal |last=Harris |first=Kathleen Mullan |last2=Woolf |first2=Steven H. |last3=Gaskin |first3=Darrell J. |date=2021-05-25 |title=High and Rising Working-Age Mortality in the US: A Report From the National Academies of Sciences, Engineering, and Medicine |url=https://doi.org/10.1001/jama.2021.4073 |journal=JAMA |volume=325 |issue=20 |pages=2045–2046 |doi=10.1001/jama.2021.4073 |issn=0098-7484}}</ref> points out that “social, economic, and cultural changes that have undermined economic security, intergenerational mobility, and social support networks can adversely affect cardiometabolic health through stress-mediated biological pathways and reduced access to care”.

Recent research indicates working conditions that may be contributing to the cardiovascular disease trends in the U.S. include,

* increases in
** annual working hours
** job stressors, such as low job control, job strain, and work-family conflict<ref>{{Cite journal |last=Myers |first=Stephanie |last2=Govindarajulu |first2=Usha |last3=Joseph |first3=Michael |last4=Landsbergis |first4=Paul |date=2019-06 |title=Changes in work characteristics over 12 years: Findings from the 2002‐2014 US National NIOSH Quality of Work Life Surveys |url=https://onlinelibrary.wiley.com/doi/10.1002/ajim.22971 |journal=American Journal of Industrial Medicine |language=en |volume=62 |issue=6 |pages=511–522 |doi=10.1002/ajim.22971 |issn=0271-3586}}</ref>
** income inequality<ref>{{Cite web |title=State of Working America Wages 2019: A story of slow, uneven, and unequal wage growth over the last 40 years |url=https://www.epi.org/publication/swa-wages-2019/ |access-date=2023-02-08 |website=Economic Policy Institute |language=en-US}}</ref><ref name=":10">{{Cite web |title=Labor Day 2019 {{!}} Working people have been thwarted in their efforts to bargain for better wages by attacks on unions |url=https://www.epi.org/publication/labor-day-2019-collective-bargaining/ |access-date=2023-02-08 |website=Economic Policy Institute |language=en-US}}</ref>
** precarious employment<ref>{{Cite journal |last=Oddo |first=Vanessa M. |last2=Zhuang |first2=Castiel Chen |last3=Andrea |first3=Sarah B. |last4=Eisenberg-Guyot |first4=Jerzy |last5=Peckham |first5=Trevor |last6=Jacoby |first6=Daniel |last7=Hajat |first7=Anjum |date=2021-04-01 |title=Changes in precarious employment in the United States: A longitudinal analysis |url=https://pubmed.ncbi.nlm.nih.gov/33283874/ |journal=Scandinavian Journal of Work, Environment & Health |volume=47 |issue=3 |pages=171–180 |doi=10.5271/sjweh.3939 |issn=1795-990X |pmc=8126438 |pmid=33283874}}</ref> (such as temporary or contract work) that involves inadequate pay, job insecurity, changes in working-time arrangements, loss of workers' rights and protections, lack of collective organization (such as unionization)
* decreases in
** union membership<ref name=":10" />
** social mobility<ref>{{Cite journal |last=Chetty |first=Raj |last2=Grusky |first2=David |last3=Hell |first3=Maximilian |last4=Hendren |first4=Nathaniel |last5=Manduca |first5=Robert |last6=Narang |first6=Jimmy |date=2017-04-28 |title=The fading American dream: Trends in absolute income mobility since 1940 |url=https://www.science.org/doi/10.1126/science.aal4617 |journal=Science |language=en |volume=356 |issue=6336 |pages=398–406 |doi=10.1126/science.aal4617 |issn=0036-8075}}</ref> (movement of people upward or downward in society through job status, education level, income, etc.)
** work intensification through new technology and "lean production" (increasing efficiency, reducing waste) techniques<ref>{{Cite journal |last=Landsbergis |first=Paul A. |last2=Cahill |first2=Janet |last3=Schnall |first3=Peter |date=1999 |title=The impact of lean production and related new systems of work organization on worker health. |url=http://doi.apa.org/getdoi.cfm?doi=10.1037/1076-8998.4.2.108 |journal=Journal of Occupational Health Psychology |language=en |volume=4 |issue=2 |pages=108–130 |doi=10.1037/1076-8998.4.2.108 |issn=1939-1307}}</ref><ref>{{Cite journal |last=Zelnick |first=Jennifer R. |last2=Abramovitz |first2=Mimi |last3=Pirutinsky |first3=Steven |date=2022-08 |title=Managerialism: A workforce health hazard in human service settings |url=https://onlinelibrary.wiley.com/doi/10.1002/ajim.23395 |journal=American Journal of Industrial Medicine |language=en |volume=65 |issue=8 |pages=669–674 |doi=10.1002/ajim.23395 |issn=0271-3586}}</ref>


==Work-related risk factors for cardiovascular disease==
==Work-related risk factors for cardiovascular disease==
Line 40: Line 59:
* Long [[Working time|work hours]] (55 or more hours per week)<ref name=":6" /><ref>{{Cite journal |last=Virtanen |first=Marianna |last2=Kivimäki |first2=Mika |date=2018-10-01 |title=Long Working Hours and Risk of Cardiovascular Disease |url=https://doi.org/10.1007/s11886-018-1049-9 |journal=Current Cardiology Reports |language=en |volume=20 |issue=11 |pages=123 |doi=10.1007/s11886-018-1049-9 |issn=1534-3170 |pmc=PMC6267375 |pmid=30276493}}</ref><ref>{{Cite journal |last1=Pega |first1=Frank |last2=Náfrádi |first2=Bálint |last3=Momen |first3=Natalie C. |last4=Ujita |first4=Yuka |last5=Streicher |first5=Kai N. |last6=Prüss-Üstün |first6=Annette M. |last7=Descatha |first7=Alexis |last8=Driscoll |first8=Tim |last9=Fischer |first9=Frida M. |last10=Godderis |first10=Lode |last11=Kiiver |first11=Hannah M. |date=2021-09-01 |title=Global, regional, and national burdens of ischemic heart disease and stroke attributable to exposure to long working hours for 194 countries, 2000–2016: A systematic analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury |url=http://dx.doi.org/10.1016/j.envint.2021.106595 |journal=Environment International |volume=154 |pages=106595 |doi=10.1016/j.envint.2021.106595 |pmid=34011457 |pmc=8204267 |issn=0160-4120}}</ref>
* Long [[Working time|work hours]] (55 or more hours per week)<ref name=":6" /><ref>{{Cite journal |last=Virtanen |first=Marianna |last2=Kivimäki |first2=Mika |date=2018-10-01 |title=Long Working Hours and Risk of Cardiovascular Disease |url=https://doi.org/10.1007/s11886-018-1049-9 |journal=Current Cardiology Reports |language=en |volume=20 |issue=11 |pages=123 |doi=10.1007/s11886-018-1049-9 |issn=1534-3170 |pmc=PMC6267375 |pmid=30276493}}</ref><ref>{{Cite journal |last1=Pega |first1=Frank |last2=Náfrádi |first2=Bálint |last3=Momen |first3=Natalie C. |last4=Ujita |first4=Yuka |last5=Streicher |first5=Kai N. |last6=Prüss-Üstün |first6=Annette M. |last7=Descatha |first7=Alexis |last8=Driscoll |first8=Tim |last9=Fischer |first9=Frida M. |last10=Godderis |first10=Lode |last11=Kiiver |first11=Hannah M. |date=2021-09-01 |title=Global, regional, and national burdens of ischemic heart disease and stroke attributable to exposure to long working hours for 194 countries, 2000–2016: A systematic analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury |url=http://dx.doi.org/10.1016/j.envint.2021.106595 |journal=Environment International |volume=154 |pages=106595 |doi=10.1016/j.envint.2021.106595 |pmid=34011457 |pmc=8204267 |issn=0160-4120}}</ref>
* Exposure to loud [[Occupational noise|noise]]<ref name=":2" /><ref>{{Cite journal|last1=Kerns|first1=Ellen|last2=Masterson|first2=Elizabeth A.|last3=Themann|first3=Christa L.|last4=Calvert|first4=Geoffrey M.|date=2018|title=Cardiovascular conditions, hearing difficulty, and occupational noise exposure within US industries and occupations|journal=American Journal of Industrial Medicine|volume=61|issue=6|pages=477–491|doi=10.1002/ajim.22833|issn=1097-0274|pmc=6897488|pmid=29537072}}</ref>
* Exposure to loud [[Occupational noise|noise]]<ref name=":2" /><ref>{{Cite journal|last1=Kerns|first1=Ellen|last2=Masterson|first2=Elizabeth A.|last3=Themann|first3=Christa L.|last4=Calvert|first4=Geoffrey M.|date=2018|title=Cardiovascular conditions, hearing difficulty, and occupational noise exposure within US industries and occupations|journal=American Journal of Industrial Medicine|volume=61|issue=6|pages=477–491|doi=10.1002/ajim.22833|issn=1097-0274|pmc=6897488|pmid=29537072}}</ref>
* The risk of [[stroke]] has also been found to be associated with exposure to [[ionizing radiation]]<ref name=":2" />
* Exposure to [[ionizing radiation]]<ref name=":2" />


Hypertension develops more often in those who experience job strain and who have shift-work.<ref name=":2" /> Differences between women and men in risk are small, however men risk having and dying of [[heart attack]]s or stroke twice as often as women during working life.<ref name=":2">{{Cite web|url=http://www.sbu.se/en/publications/sbu-assesses/occupational-exposures-and-cardiovascular-disease/ |title=Occupational Exposures and Cardiovascular Disease |publisher = Statens beredning för medicinsk och social utvärdering (SBU); Swedish Agency for Health Technology Assessment and Assessment of Social Services |language=en |access-date=2017-06-01 |date=2015-08-26 }}</ref>
Hypertension develops more often in those who experience job strain and who have shift-work.<ref name=":2" /> Differences between women and men in risk are small, however men risk having and dying of [[heart attack]]s or stroke twice as often as women during working life.<ref name=":2">{{Cite web|url=http://www.sbu.se/en/publications/sbu-assesses/occupational-exposures-and-cardiovascular-disease/ |title=Occupational Exposures and Cardiovascular Disease |publisher = Statens beredning för medicinsk och social utvärdering (SBU); Swedish Agency for Health Technology Assessment and Assessment of Social Services |language=en |access-date=2017-06-01 |date=2015-08-26 }}</ref>

Revision as of 21:04, 8 February 2023

Occupational cardiovascular disease
SpecialtyCardiology

Occupational cardiovascular diseases are diseases of the heart or blood vessels caused by working conditions, making them a form of occupational illness. These diseases include coronary heart disease, stroke, cardiomyopathy, arrythmia, and heart valve or heart chamber problems. Cardiovascular disease is the leading cause of death in the United States and worldwide.[1][2] In the United States, cardiovascular diseases account for one out of four deaths.[3] The 6th International Conference on Work Environment and Cardiovascular Diseases found that within the working age population about 10-20% of cardiovascular disease deaths can be attributed to work.[4] Ten workplace stressors (shift work, job insecurity, high job demand, etc.) were estimated to be associated with 120,000 U.S. deaths each year and account for 5-8% of health care costs.[5]

Research related to the association between work and cardiovascular disease is on-going. Links have been established between cardiovascular disease risk and occupational exposure to chemicals, noise, psychosocial stressors, physical activity, and certain workplace organization factors. Additionally, work-related risk factors for cardiovascular disease may also increase the risk of other cardiovascular disease risk factors such as hypertension[6][7], diabetes[8][9][10], obesity[11][12], unhealthy diet[13], leisure-time physical inactivity[12], and excessive alcohol use[14]. Work may also increase risk of depression[15], burnout[16], sleeping problems[17], and physiological and cardiorespiratory stress mechanisms in the body which may also affect the risk for cardiovascular disease.

United States trends in cardiovascular disease and the impact of work

Age-adjusted cardiovascular disease death rates in the U.S. are no longer declining, as they previously had been since the 1960s.[18] Cardiovascular disease death rates are increasing in older (45-64 years) working-age people.[19] In fact, death rates from all causes have been increasing since about 2012 in working-age people (25-64 years), primarily due to increases in drug (mainly opioid) overdoses, alcohol abuse, suicides, and chronic diseases, such as cardiovascular diseases, hypertension and diabetes.[18] Between 2000-2015, the cardiovascular disease mortality gap between the U.S. and other wealthy countries has widened.[20] These trends are occurring despite improvements in the medical treatment of cardiovascular diseases. Primary prevention of cardiovascular diseases, including workplace health promotion, is key to reducing death rates.

Related explanations for cardiovascular disease trends are increases in the prevalence of other stress-related (including work-related stress) conditions, obesity[21], diabetes[21], metabolic syndrome[21], and short sleeping hours[22]. The age-adjusted prevalence of hypertension increased in the U.S. between 1988-2010 and increased again between 2010-2018 for most gender-race groups[21]. Mental health disorders, including depression and anxiety, are increasing globally and in the U.S.[23][24]

A 2021 National Academy of Sciences report[25] points out that “social, economic, and cultural changes that have undermined economic security, intergenerational mobility, and social support networks can adversely affect cardiometabolic health through stress-mediated biological pathways and reduced access to care”.

Recent research indicates working conditions that may be contributing to the cardiovascular disease trends in the U.S. include,

  • increases in
    • annual working hours
    • job stressors, such as low job control, job strain, and work-family conflict[26]
    • income inequality[27][28]
    • precarious employment[29] (such as temporary or contract work) that involves inadequate pay, job insecurity, changes in working-time arrangements, loss of workers' rights and protections, lack of collective organization (such as unionization)
  • decreases in
    • union membership[28]
    • social mobility[30] (movement of people upward or downward in society through job status, education level, income, etc.)
    • work intensification through new technology and "lean production" (increasing efficiency, reducing waste) techniques[31][32]

Work-related risk factors for cardiovascular disease

Hypertension develops more often in those who experience job strain and who have shift-work.[37] Differences between women and men in risk are small, however men risk having and dying of heart attacks or stroke twice as often as women during working life.[37]

A 2017 SBU report found evidence that workplace exposure to silica dust, engine exhaust or welding fumes is associated with heart disease.[45] Associations also exist for exposure to arsenic, benzopyrenes, lead, dynamite, carbon disulphide, carbon monoxide, metalworking fluids and occupational exposure to tobacco smoke.[45] Working with the electrolytic production of aluminum or the production of paper when the sulphate pulping process is used is associated with heart disease.[45] An association was also found between heart disease and exposure to compounds which are no longer permitted in certain work environments, such as phenoxy acids containing TCDD(dioxin) or asbestos.[45]

Workplace exposure to silica dust or asbestos is also associated with pulmonary heart disease. There is evidence that workplace exposure to lead, carbon disulphide, phenoxy acids containing TCDD, as well as working in an environment where aluminum is being electrolytically produced, is associated with stroke.[45]

Occupations at higher risk for cardiovascular disease

  • Firefighters[46]
  • Police officers[46]
  • NFL Players[46]
  • Long-haul truck drivers[46]

Occupational cardiovascular disease in firefighters

Given the many hazards present during career firefighting, firefighters are at a greater risk for occupational cardiovascular disease. CVD is the leading most cause of death in firefighters, and accounts for 45% of on-duty deaths.[47] About 90% of CVD in firefighters is attributed to coronary heart disease.[33] Other researchers have found that blood plasma volume decreases after just minutes of firefighting which increases blood pressure and causes the heart to work harder to distribute blood systemically. Firefighting has also shown to increase arterial stiffness and overall cardiovascular strain.[40] In a study by Barger, et al., a positive screening for a sleep disorder increased the odds a firefighter would also have cardiovascular disease (OR = 2.37, 95% CI 1.54-3.66, p < 0.0001).[48]

Group of firefighters in gear carrying a long hose to the fire scene
Group of firefighters in gear carrying a long hose to the fire scene.

CVD risk factors in firefighting

See also

References

  1. ^ "National vital statistics report ; v. 70, no. 9". 2021-07-01. doi:10.15620/cdc:107021. {{cite journal}}: Cite journal requires |journal= (help)
  2. ^ "The top 10 causes of death". www.who.int. Retrieved 2023-02-08.
  3. ^ Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, et al. (American Heart Association Council on Epidemiology and Prevention Statistics Committee and Stroke Statistics Subcommittee) (March 2019). "Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association". Circulation. 139 (10): e56–e528. doi:10.1161/CIR.0000000000000659. PMID 30700139.
  4. ^ Tsutsumi, Akizumi (2015). "Prevention and management of work-related cardiovascular disorders". International Journal of Occupational Medicine and Environmental Health. 28 (1): 4–7. doi:10.2478/s13382-014-0319-z. ISSN 1896-494X. PMID 26159941.
  5. ^ Goh, Joel; Pfeffer, Jeffrey; Zenios, Stefanos A. (2016-02). "The Relationship Between Workplace Stressors and Mortality and Health Costs in the United States". Management Science. 62 (2): 608–628. doi:10.1287/mnsc.2014.2115. ISSN 0025-1909. {{cite journal}}: Check date values in: |date= (help)
  6. ^ Bolm-Audorff, Ulrich; Hegewald, Janice; Pretzsch, Anna; Freiberg, Alice; Nienhaus, Albert; Seidler, Andreas (2020-01). "Occupational Noise and Hypertension Risk: A Systematic Review and Meta-Analysis". International Journal of Environmental Research and Public Health. 17 (17): 6281. doi:10.3390/ijerph17176281. ISSN 1660-4601. PMC 7504405. PMID 32872306. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  7. ^ Teixeira, Liliane R.; Pega, Frank; Dzhambov, Angel M.; Bortkiewicz, Alicja; da Silva, Denise T. Correa; de Andrade, Carlos A. F.; Gadzicka, Elzbieta; Hadkhale, Kishor; Iavicoli, Sergio; Martínez-Silveira, Martha S.; Pawlaczyk-Łuszczyńska, Małgorzata; Rondinone, Bruna M.; Siedlecka, Jadwiga; Valenti, Antonio; Gagliardi, Diana (2021-09-01). "The effect of occupational exposure to noise on ischaemic heart disease, stroke and hypertension: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-Related Burden of Disease and Injury". Environment International. 154: 106387. doi:10.1016/j.envint.2021.106387. ISSN 0160-4120. PMC 8204276. PMID 33612311.{{cite journal}}: CS1 maint: PMC format (link)
  8. ^ Cosgrove, M. P.; Sargeant, L. A.; Caleyachetty, R.; Griffin, S. J. (2012-02-14). "Work-related stress and Type 2 diabetes: systematic review and meta-analysis". Occupational Medicine. 62 (3): 167–173. doi:10.1093/occmed/kqs002. ISSN 0962-7480.
  9. ^ Sui, Hua; Sun, Nijing; Zhan, Libin; Lu, Xiaoguang; Chen, Tuo; Mao, Xinyong (2016-08-11). "Association between Work-Related Stress and Risk for Type 2 Diabetes: A Systematic Review and Meta-Analysis of Prospective Cohort Studies". PLOS ONE. 11 (8): e0159978. doi:10.1371/journal.pone.0159978. ISSN 1932-6203. PMC 4981307. PMID 27513574.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  10. ^ Krajnak, Kristine M. (2014-01). "Potential Contribution of Work-Related Psychosocial Stress to the Development of Cardiovascular Disease and Type II Diabetes: A Brief Review". Environmental Health Insights. 8s1: EHI.S15263. doi:10.4137/EHI.S15263. ISSN 1178-6302. PMC 4251185. PMID 25525370. {{cite journal}}: Check date values in: |date= (help)CS1 maint: PMC format (link)
  11. ^ Geda, Nigatu Regassa; Feng, Cindy Xin; Yu, Yamei (2022-03-29). "Examining the association between work stress, life stress and obesity among working adult population in Canada: findings from a nationally representative data". Archives of Public Health. 80 (1): 97. doi:10.1186/s13690-022-00865-8. ISSN 2049-3258. PMC 8966340. PMID 35351179.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  12. ^ a b van den Berge, Mandy; van der Beek, Allard J.; Türkeli, Rukiye; van Kalken, Marike; Hulsegge, Gerben (2021-05-01). "Work-related physical and psychosocial risk factors cluster with obesity, smoking and physical inactivity". International Archives of Occupational and Environmental Health. 94 (4): 741–750. doi:10.1007/s00420-020-01627-1. ISSN 1432-1246. PMC 8068657. PMID 33409697.{{cite journal}}: CS1 maint: PMC format (link)
  13. ^ "The effect of shift work on eating habits on JSTOR". www.jstor.org. Retrieved 2023-02-08.
  14. ^ Frone, M. R. (1999). "Work stress and alcohol use". Alcohol Research & Health: The Journal of the National Institute on Alcohol Abuse and Alcoholism. 23 (4): 284–291. ISSN 1535-7414. PMC 6760381. PMID 10890825.
  15. ^ Rugulies, Reiner; Sørensen, Kathrine; Di Tecco, Cristina; Bonafede, Michela; Rondinone, Bruna M.; Ahn, Seoyeon; Ando, Emiko; Ayuso-Mateos, Jose Luis; Cabello, Maria; Descatha, Alexis; Dragano, Nico; Durand-Moreau, Quentin; Eguchi, Hisashi; Gao, Junling; Godderis, Lode (2021-10-01). "The effect of exposure to long working hours on depression: A systematic review and meta-analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury". Environment International. 155: 106629. doi:10.1016/j.envint.2021.106629. ISSN 0160-4120.
  16. ^ Salvagioni, Denise Albieri Jodas; Melanda, Francine Nesello; Mesas, Arthur Eumann; González, Alberto Durán; Gabani, Flávia Lopes; Andrade, Selma Maffei de (2017-10-04). "Physical, psychological and occupational consequences of job burnout: A systematic review of prospective studies". PLOS ONE. 12 (10): e0185781. doi:10.1371/journal.pone.0185781. ISSN 1932-6203. PMC 5627926. PMID 28977041.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  17. ^ Litwiller, Brett; Snyder, Lori Anderson; Taylor, William D.; Steele, Logan M. (2017-04). "The relationship between sleep and work: A meta-analysis". Journal of Applied Psychology. 102 (4): 682–699. doi:10.1037/apl0000169. ISSN 1939-1854. {{cite journal}}: Check date values in: |date= (help)
  18. ^ a b Woolf, Steven H.; Schoomaker, Heidi (2019-11-26). "Life Expectancy and Mortality Rates in the United States, 1959-2017". JAMA. 322 (20): 1996–2016. doi:10.1001/jama.2019.16932. ISSN 1538-3598. PMC 7146991. PMID 31769830.
  19. ^ "Trends in cancer and heart disease death rates among adults aged 45–64: United States, 1999–2017". stacks.cdc.gov. Retrieved 2023-02-08.
  20. ^ www.nationalacademies.org https://www.nationalacademies.org/ocga/testimony-before-congress/high-and-rising-mortality-rates-among-working-age-adults. Retrieved 2023-02-08. {{cite web}}: Missing or empty |title= (help)
  21. ^ a b c d Tsao, Connie W.; Aday, Aaron W.; Almarzooq, Zaid I.; Alonso, Alvaro; Beaton, Andrea Z.; Bittencourt, Marcio S.; Boehme, Amelia K.; Buxton, Alfred E.; Carson, April P.; Commodore-Mensah, Yvonne; Elkind, Mitchell S.V.; Evenson, Kelly R.; Eze-Nliam, Chete; Ferguson, Jane F.; Generoso, Giuliano (2022-02-22). "Heart Disease and Stroke Statistics—2022 Update: A Report From the American Heart Association". Circulation. 145 (8). doi:10.1161/CIR.0000000000001052. ISSN 0009-7322.
  22. ^ Sheehan, Connor M.; Frochen, Stephen E.; Walsemann, Katrina M.; Ailshire, Jennifer A. (2019-02-01). "Are U.S. adults reporting less sleep?: Findings from sleep duration trends in the National Health Interview Survey, 2004-2017". Sleep. 42 (2): zsy221. doi:10.1093/sleep/zsy221. ISSN 1550-9109. PMC 6941709. PMID 30452725.
  23. ^ World Health Organization (2017). "Depression and other common mental disorders: global health estimates". {{cite journal}}: Cite journal requires |journal= (help)
  24. ^ Olfson, Mark; Wang, Shuai; Wall, Melanie; Marcus, Steven C.; Blanco, Carlos (2019-02-01). "Trends in Serious Psychological Distress and Outpatient Mental Health Care of US Adults". JAMA psychiatry. 76 (2): 152–161. doi:10.1001/jamapsychiatry.2018.3550. ISSN 2168-6238. PMC 6439744. PMID 30484838.
  25. ^ Harris, Kathleen Mullan; Woolf, Steven H.; Gaskin, Darrell J. (2021-05-25). "High and Rising Working-Age Mortality in the US: A Report From the National Academies of Sciences, Engineering, and Medicine". JAMA. 325 (20): 2045–2046. doi:10.1001/jama.2021.4073. ISSN 0098-7484.
  26. ^ Myers, Stephanie; Govindarajulu, Usha; Joseph, Michael; Landsbergis, Paul (2019-06). "Changes in work characteristics over 12 years: Findings from the 2002‐2014 US National NIOSH Quality of Work Life Surveys". American Journal of Industrial Medicine. 62 (6): 511–522. doi:10.1002/ajim.22971. ISSN 0271-3586. {{cite journal}}: Check date values in: |date= (help)
  27. ^ "State of Working America Wages 2019: A story of slow, uneven, and unequal wage growth over the last 40 years". Economic Policy Institute. Retrieved 2023-02-08.
  28. ^ a b "Labor Day 2019 | Working people have been thwarted in their efforts to bargain for better wages by attacks on unions". Economic Policy Institute. Retrieved 2023-02-08.
  29. ^ Oddo, Vanessa M.; Zhuang, Castiel Chen; Andrea, Sarah B.; Eisenberg-Guyot, Jerzy; Peckham, Trevor; Jacoby, Daniel; Hajat, Anjum (2021-04-01). "Changes in precarious employment in the United States: A longitudinal analysis". Scandinavian Journal of Work, Environment & Health. 47 (3): 171–180. doi:10.5271/sjweh.3939. ISSN 1795-990X. PMC 8126438. PMID 33283874.
  30. ^ Chetty, Raj; Grusky, David; Hell, Maximilian; Hendren, Nathaniel; Manduca, Robert; Narang, Jimmy (2017-04-28). "The fading American dream: Trends in absolute income mobility since 1940". Science. 356 (6336): 398–406. doi:10.1126/science.aal4617. ISSN 0036-8075.
  31. ^ Landsbergis, Paul A.; Cahill, Janet; Schnall, Peter (1999). "The impact of lean production and related new systems of work organization on worker health". Journal of Occupational Health Psychology. 4 (2): 108–130. doi:10.1037/1076-8998.4.2.108. ISSN 1939-1307.
  32. ^ Zelnick, Jennifer R.; Abramovitz, Mimi; Pirutinsky, Steven (2022-08). "Managerialism: A workforce health hazard in human service settings". American Journal of Industrial Medicine. 65 (8): 669–674. doi:10.1002/ajim.23395. ISSN 0271-3586. {{cite journal}}: Check date values in: |date= (help)
  33. ^ a b c d e f g h i j k Soteriades, Elpidoforos S.; Smith, Denise L.; Tsismenakis, Antonios J.; Baur, Dorothee M.; Kales, Stefanos N. (July 2011). "Cardiovascular Disease in US Firefighters: A Systematic Review". Cardiology in Review. 19 (4): 202–215. doi:10.1097/CRD.0b013e318215c105. ISSN 1061-5377. PMID 21646874. S2CID 9875120.
  34. ^ Niedhammer, Isabelle; Bertrais, Sandrine; Witt, Katrina (2021-10-01). "Psychosocial work exposures and health outcomes: a meta-review of 72 literature reviews with meta-analysis". Scandinavian Journal of Work, Environment & Health. 47 (7): 489–508. doi:10.5271/sjweh.3968. ISSN 0355-3140. PMC 8504166. PMID 34042163.{{cite journal}}: CS1 maint: PMC format (link)
  35. ^ Taouk, Yamna; Spittal, Matthew J; LaMontagne, Anthony D; Milner, Allison J (2020-01). "Psychosocial work stressors and risk of all-cause and coronary heart disease mortality: A systematic review and meta-analysis". Scandinavian Journal of Work, Environment & Health. 46 (1): 19–31. doi:10.5271/sjweh.3854. ISSN 0355-3140. {{cite journal}}: Check date values in: |date= (help)
  36. ^ Nyberg, Solja T.; Fransson, Eleonor I.; Heikkilä, Katriina; Alfredsson, Lars; Casini, Annalisa; Clays, Els; Bacquer, Dirk De; Dragano, Nico; Erbel, Raimund; Ferrie, Jane E.; Hamer, Mark; Jöckel, Karl-Heinz; Kittel, France; Knutsson, Anders; Ladwig, Karl-Heinz (2013-06-20). "Job Strain and Cardiovascular Disease Risk Factors: Meta-Analysis of Individual-Participant Data from 47,000 Men and Women". PLOS ONE. 8 (6): e67323. doi:10.1371/journal.pone.0067323. ISSN 1932-6203. PMC 3688665. PMID 23840664.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  37. ^ a b c d e f g h "Occupational Exposures and Cardiovascular Disease". Statens beredning för medicinsk och social utvärdering (SBU); Swedish Agency for Health Technology Assessment and Assessment of Social Services. 2015-08-26. Retrieved 2017-06-01.
  38. ^ Xu, Tianwei. "Workplace bullying and workplace violence as risk factors for cardiovascular disease: a multi-cohort study". academic.oup.com. doi:10.1093/eurheartj/ehy683. Retrieved 2023-02-08.
  39. ^ Virtanen, Marianna; Nyberg, Solja T.; Batty, G. David; Jokela, Markus; Heikkilä, Katriina; Fransson, Eleonor I.; Alfredsson, Lars; Bjorner, Jakob B.; Borritz, Marianne; Burr, Hermann; Casini, Annalisa; Clays, Els; Bacquer, Dirk De; Dragano, Nico; Elovainio, Marko (2013-08-08). "Perceived job insecurity as a risk factor for incident coronary heart disease: systematic review and meta-analysis". BMJ. 347: f4746. doi:10.1136/bmj.f4746. ISSN 1756-1833. PMC 3738256. PMID 23929894.{{cite journal}}: CS1 maint: PMC format (link)
  40. ^ a b Smith, Denise L; Barr, David A; Kales, Stefanos N (2013-02-01). "Extreme sacrifice: sudden cardiac death in the US Fire Service". Extreme Physiology & Medicine. 2 (1): 6. doi:10.1186/2046-7648-2-6. ISSN 2046-7648. PMC 3710100. PMID 23849605.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  41. ^ a b Rivera, Adovich S.; Akanbi, Maxwell; O’Dwyer, Linda C.; McHugh, Megan (2020-04-02). "Shift work and long work hours and their association with chronic health conditions: A systematic review of systematic reviews with meta-analyses". PLOS ONE. 15 (4): e0231037. doi:10.1371/journal.pone.0231037. ISSN 1932-6203. PMC 7117719. PMID 32240254.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  42. ^ Virtanen, Marianna; Kivimäki, Mika (2018-10-01). "Long Working Hours and Risk of Cardiovascular Disease". Current Cardiology Reports. 20 (11): 123. doi:10.1007/s11886-018-1049-9. ISSN 1534-3170. PMC 6267375. PMID 30276493.{{cite journal}}: CS1 maint: PMC format (link)
  43. ^ Pega, Frank; Náfrádi, Bálint; Momen, Natalie C.; Ujita, Yuka; Streicher, Kai N.; Prüss-Üstün, Annette M.; Descatha, Alexis; Driscoll, Tim; Fischer, Frida M.; Godderis, Lode; Kiiver, Hannah M. (2021-09-01). "Global, regional, and national burdens of ischemic heart disease and stroke attributable to exposure to long working hours for 194 countries, 2000–2016: A systematic analysis from the WHO/ILO Joint Estimates of the Work-related Burden of Disease and Injury". Environment International. 154: 106595. doi:10.1016/j.envint.2021.106595. ISSN 0160-4120. PMC 8204267. PMID 34011457.
  44. ^ Kerns, Ellen; Masterson, Elizabeth A.; Themann, Christa L.; Calvert, Geoffrey M. (2018). "Cardiovascular conditions, hearing difficulty, and occupational noise exposure within US industries and occupations". American Journal of Industrial Medicine. 61 (6): 477–491. doi:10.1002/ajim.22833. ISSN 1097-0274. PMC 6897488. PMID 29537072.
  45. ^ a b c d e "Occupational health and safety – chemical exposure". Statens beredning för medicinsk och social utvärdering (SBU); Swedish Agency for Health Technology Assessment and Assessment of Social Services. Archived from the original on 2017-06-06. Retrieved 2017-06-01.
  46. ^ a b c d "CDC - Specific Studies of Occupational Factors and CVD - NIOSH Workplace Safety and Health Topic". www.cdc.gov. 2018-11-08. Retrieved 2020-04-14.
  47. ^ Soteriades, Elpidoforos; Smith, Denise; Tsismenakis, Antonios; Baur, Dorothee; Kales, Stefanos (July 2011). "Cardiovascular Disease in US Firefighters: A Systematic Review". Cardiology in Review. 19 (4): 202–215. doi:10.1097/CRD.0b013e318215c105. ISSN 1061-5377. PMID 21646874. S2CID 9875120.
  48. ^ a b Barger LK, Rajaratnam SM, Wang W, O'Brien CS, Sullivan JP, Qadri S, et al. (March 2015). "Common sleep disorders increase risk of motor vehicle crashes and adverse health outcomes in firefighters". Journal of Clinical Sleep Medicine. 11 (3): 233–40. doi:10.5664/jcsm.4534. PMC 4346644. PMID 25580602.
  49. ^ Meier-Ewert, Hans K; Ridker, Paul M; Rifai, Nader; Regan, Meredith M; Price, Nick J; Dinges, David F; Mullington, Janet M (February 2004). "Effect of sleep loss on C-Reactive protein, an inflammatory marker of cardiovascular risk". Journal of the American College of Cardiology. 43 (4): 678–683. doi:10.1016/j.jacc.2003.07.050. PMID 14975482.