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Prashant P. Sharma is an Indian-American invertebrate biologist and a professor of Integrative Biology at the University of Wisconsin-Madison.^[1]

Education

Sharma attended Harvard University and completed his undergraduate training in 2006. He earned his Ph.D. from Harvard University in 2012. He was a National Science Foundation postdoctoral fellow at the American Museum of Natural History.

Career

Sharma joined the University of Wisconsin-Madison in 2015. His research group works on phylogenomics, evolutionary developmental biology, and comparative genomics of ancient invertebrate groups, with emphasis on chelicerate arthropods. He is the director of the Zoology Museum of the University of Wisconsin-Madison. He received a distinguished Class of 1955 Teaching Excellence Award.^[2]^[3]

His early work focused on the systematics and biogeography of the armored harvestmen (Laniatores) from the South Pacific. In 2011, he described three new families of harvestmen from the Paleotropics and showed that one family of armored harvestmen is capable of extreme dispersal, in contrast to the rest of this arachnid order.^[4] His research group later discovered a suborder of fossil daddy-long-legs with four eyes called Tetraophthalmi, whereas all living species only have two eyes.^[5]^[6]

His group is best known for using genome duplications to understand the relationships of arachnids. He proposed a grouping of arachnids with book lungs as well as pseudoscorpions, which is called "Arachnopulmonata" and is united by a shared whole genome duplication.^[7]^[8]^[9]^[10] He proposed that horseshoe crabs are part of Arachnida and that arachnids independently colonized land more than once,^[11] using both genomes and fossils.^[8]^[10]

His laboratory works on the genetics and development of daddy-long-legs (Opiliones or "harvestmen") and spiders. He previously showed that spiders recycled leg-patterning genes to make the segments of their heads, an example of an evolutionary process called cooption.^[12]^[13] His team later showed that a gene duplicate restricted to Arachnopulmonata is responsible for making all eye types of spiders.^[14] In 2021, his group sequenced the first Opiliones genome and created "daddy-short-legs" using gene silencing to understand how daddy-long-legs make their long legs.^[15]^[16]

References

^ "New professor turns to arachnids to solve evolutionary puzzles | College of Letters & Science, University of Wisconsin-Madison". ls.wisc.edu. Retrieved 2023-05-09.
^ Auger, Ian (2023-01-30). "UW awards Distinguished Teaching Awards to twelve faculty". The Badger Herald. Retrieved 2023-05-09.
^ "Meet the 2023 Distinguished Teaching Award recipients". news.wisc.edu. Retrieved 2023-05-09.
^ "Arachnids crossed the Pacific". Nature. 485 (7400): 550–550. 2012-05. doi:10.1038/485550a. ISSN 0028-0836. {{cite journal}}: Check date values in: |date= (help)
^ Blaszczak-Boxe,LiveScience, Agata. "Four-Eyed 'Daddy Longlegs' Fossil Discovered". Scientific American. Retrieved 2023-05-10.
^ "Daddy longlegs once had four eyes, research says". PBS NewsHour. 2014-04-11. Retrieved 2023-05-10.
^ Sharma, Prashant P.; Kaluziak, Stefan T.; Pérez-Porro, Alicia R.; González, Vanessa L.; Hormiga, Gustavo; Wheeler, Ward C.; Giribet, Gonzalo (November 2014). "Phylogenomic Interrogation of Arachnida Reveals Systemic Conflicts in Phylogenetic Signal". Molecular Biology and Evolution. 31 (11): 2963–2984. doi:10.1093/molbev/msu235. ISSN 1537-1719.
^ ^a ^b Ballesteros, Jesús A; Sharma, Prashant P (2019-11-01). Halanych, Ken (ed.). "A Critical Appraisal of the Placement of Xiphosura (Chelicerata) with Account of Known Sources of Phylogenetic Error". Systematic Biology. 68 (6): 896–917. doi:10.1093/sysbio/syz011. ISSN 1063-5157.
^ Ontano, Andrew Z; Gainett, Guilherme; Aharon, Shlomi; Ballesteros, Jesús A; Benavides, Ligia R; Corbett, Kevin F; Gavish-Regev, Efrat; Harvey, Mark S; Monsma, Scott; Santibáñez-López, Carlos E; Setton, Emily V W; Zehms, Jakob T; Zeh, Jeanne A; Zeh, David W; Sharma, Prashant P (2021-05-19). Pupko, Tal (ed.). "Taxonomic Sampling and Rare Genomic Changes Overcome Long-Branch Attraction in the Phylogenetic Placement of Pseudoscorpions". Molecular Biology and Evolution. 38 (6): 2446–2467. doi:10.1093/molbev/msab038. ISSN 1537-1719. PMC 8136511. PMID 33565584.
^ ^a ^b Ballesteros, Jesús A; Santibáñez-López, Carlos E; Baker, Caitlin M; Benavides, Ligia R; Cunha, Tauana J; Gainett, Guilherme; Ontano, Andrew Z; Setton, Emily V W; Arango, Claudia P; Gavish-Regev, Efrat; Harvey, Mark S; Wheeler, Ward C; Hormiga, Gustavo; Giribet, Gonzalo; Sharma, Prashant P (2022-02-03). Teeling, Emma (ed.). "Comprehensive Species Sampling and Sophisticated Algorithmic Approaches Refute the Monophyly of Arachnida". Molecular Biology and Evolution. 39 (2): msac021. doi:10.1093/molbev/msac021. ISSN 0737-4038. PMC 8845124. PMID 35137183.
^ Greenwood, Veronique (2022-02-18). "Act of 'Heresy' Adds Horseshoe Crabs to Arachnid Family Tree". The New York Times. ISSN 0362-4331. Retrieved 2023-05-09.
^ "Leg genes give spiders segmented heads". cosmosmagazine.com. 2018-03-27. Retrieved 2023-05-10.
^ Setton, Emily V. W.; Sharma, Prashant P. (2018-04-10). "Cooption of an appendage-patterning gene cassette in the head segmentation of arachnids". Proceedings of the National Academy of Sciences. 115 (15). doi:10.1073/pnas.1720193115. ISSN 0027-8424. PMC 5899462. PMID 29581309.{{cite journal}}: CS1 maint: PMC format (link)
^ Gainett, Guilherme; Ballesteros, Jesús A.; Kanzler, Charlotte R.; Zehms, Jakob T.; Zern, John M.; Aharon, Shlomi; Gavish-Regev, Efrat; Sharma, Prashant P. (2020-12). "Systemic paralogy and function of retinal determination network homologs in arachnids". BMC Genomics. 21 (1): 811. doi:10.1186/s12864-020-07149-x. ISSN 1471-2164. {{cite journal}}: Check date values in: |date= (help)CS1 maint: unflagged free DOI (link)
^ Wu, Katherine J. (2021-08-03). "You've Never Seen Legs Like These". The Atlantic. Retrieved 2023-05-09.
^ "How the daddy-long-legs gets long legs". Nature. 596 (7871): 167–167. 2021-08-05. doi:10.1038/d41586-021-02127-z.

External links

Prashant Sharma: University of Wisconsin-Madison faculty page

Prashant P. Sharma publications indexed by Google Scholar

This article about a biologist from the United States is a stub. You can help Wikipedia by expanding it.

[1] "New professor turns to arachnids to solve evolutionary puzzles | College of Letters & Science, University of Wisconsin-Madison". ls.wisc.edu. Retrieved 2023-05-09.

[2] Auger, Ian (2023-01-30). "UW awards Distinguished Teaching Awards to twelve faculty". The Badger Herald. Retrieved 2023-05-09.

[3] "Meet the 2023 Distinguished Teaching Award recipients". news.wisc.edu. Retrieved 2023-05-09.

[4] "Arachnids crossed the Pacific". Nature. 485 (7400): 550–550. 2012-05. doi:10.1038/485550a. ISSN 0028-0836. {{cite journal}}: Check date values in: |date= (help)

[5] Blaszczak-Boxe,LiveScience, Agata. "Four-Eyed 'Daddy Longlegs' Fossil Discovered". Scientific American. Retrieved 2023-05-10.

[6] "Daddy longlegs once had four eyes, research says". PBS NewsHour. 2014-04-11. Retrieved 2023-05-10.

[7] Sharma, Prashant P.; Kaluziak, Stefan T.; Pérez-Porro, Alicia R.; González, Vanessa L.; Hormiga, Gustavo; Wheeler, Ward C.; Giribet, Gonzalo (November 2014). "Phylogenomic Interrogation of Arachnida Reveals Systemic Conflicts in Phylogenetic Signal". Molecular Biology and Evolution. 31 (11): 2963–2984. doi:10.1093/molbev/msu235. ISSN 1537-1719.

[:0-8] Ballesteros, Jesús A; Sharma, Prashant P (2019-11-01). Halanych, Ken (ed.). "A Critical Appraisal of the Placement of Xiphosura (Chelicerata) with Account of Known Sources of Phylogenetic Error". Systematic Biology. 68 (6): 896–917. doi:10.1093/sysbio/syz011. ISSN 1063-5157.

[9] Ontano, Andrew Z; Gainett, Guilherme; Aharon, Shlomi; Ballesteros, Jesús A; Benavides, Ligia R; Corbett, Kevin F; Gavish-Regev, Efrat; Harvey, Mark S; Monsma, Scott; Santibáñez-López, Carlos E; Setton, Emily V W; Zehms, Jakob T; Zeh, Jeanne A; Zeh, David W; Sharma, Prashant P (2021-05-19). Pupko, Tal (ed.). "Taxonomic Sampling and Rare Genomic Changes Overcome Long-Branch Attraction in the Phylogenetic Placement of Pseudoscorpions". Molecular Biology and Evolution. 38 (6): 2446–2467. doi:10.1093/molbev/msab038. ISSN 1537-1719. PMC 8136511. PMID 33565584.

[:1-10] Ballesteros, Jesús A; Santibáñez-López, Carlos E; Baker, Caitlin M; Benavides, Ligia R; Cunha, Tauana J; Gainett, Guilherme; Ontano, Andrew Z; Setton, Emily V W; Arango, Claudia P; Gavish-Regev, Efrat; Harvey, Mark S; Wheeler, Ward C; Hormiga, Gustavo; Giribet, Gonzalo; Sharma, Prashant P (2022-02-03). Teeling, Emma (ed.). "Comprehensive Species Sampling and Sophisticated Algorithmic Approaches Refute the Monophyly of Arachnida". Molecular Biology and Evolution. 39 (2): msac021. doi:10.1093/molbev/msac021. ISSN 0737-4038. PMC 8845124. PMID 35137183.

[11] Greenwood, Veronique (2022-02-18). "Act of 'Heresy' Adds Horseshoe Crabs to Arachnid Family Tree". The New York Times. ISSN 0362-4331. Retrieved 2023-05-09.

[12] "Leg genes give spiders segmented heads". cosmosmagazine.com. 2018-03-27. Retrieved 2023-05-10.

[13] Setton, Emily V. W.; Sharma, Prashant P. (2018-04-10). "Cooption of an appendage-patterning gene cassette in the head segmentation of arachnids". Proceedings of the National Academy of Sciences. 115 (15). doi:10.1073/pnas.1720193115. ISSN 0027-8424. PMC 5899462. PMID 29581309.{{cite journal}}: CS1 maint: PMC format (link)

[14] Gainett, Guilherme; Ballesteros, Jesús A.; Kanzler, Charlotte R.; Zehms, Jakob T.; Zern, John M.; Aharon, Shlomi; Gavish-Regev, Efrat; Sharma, Prashant P. (2020-12). "Systemic paralogy and function of retinal determination network homologs in arachnids". BMC Genomics. 21 (1): 811. doi:10.1186/s12864-020-07149-x. ISSN 1471-2164. {{cite journal}}: Check date values in: |date= (help)CS1 maint: unflagged free DOI (link)

[15] Wu, Katherine J. (2021-08-03). "You've Never Seen Legs Like These". The Atlantic. Retrieved 2023-05-09.

[16] "How the daddy-long-legs gets long legs". Nature. 596 (7871): 167–167. 2021-08-05. doi:10.1038/d41586-021-02127-z.

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 '''Prashant P. Sharma''' is an Indian-American [[Invertebrate zoology|invertebrate biologist]] and a professor of Integrative Biology at the [[University of Wisconsin–Madison|University of Wisconsin-Madison]].<ref>{{Cite web |title=New professor turns to arachnids to solve evolutionary puzzles {{!}} College of Letters & Science, University of Wisconsin-Madison |url=https://ls.wisc.edu/news/prashant-sharma-new-professor-turns-to-arachnids-to-solve-evolutionary-puzzles-3 |access-date=2023-05-09 |website=ls.wisc.edu}}</ref>
+== Education ==
+Sharma attended Harvard University and completed his undergraduate training in 2006. He earned his Ph.D. from Harvard University in 2012. He was a National Science Foundation postdoctoral fellow at the American Museum of Natural History.
 == Career ==
-His research group works on [[phylogenomics]], [[evolutionary developmental biology]], and [[comparative genomics]] of ancient invertebrate groups, with emphasis on [[Chelicerata|chelicerate arthropods]]. He is the director of the Zoology Museum of the University of Wisconsin-Madison. He received a distinguished Class of 1955 Teaching Excellence Award.<ref>{{Cite web |last=Auger |first=Ian |date=2023-01-30 |title=UW awards Distinguished Teaching Awards to twelve faculty |url=https://badgerherald.com/news/2023/01/30/uw-awards-distinguished-teaching-awards-to-twelve-faculty |access-date=2023-05-09 |website=The Badger Herald}}</ref><ref>{{Cite web |title=Meet the 2023 Distinguished Teaching Award recipients |url=https://news.wisc.edu/meet-the-2023-distinguished-teaching-award-recipients-2/ |access-date=2023-05-09 |website=news.wisc.edu |language=en-US}}</ref>
+Sharma joined the University of Wisconsin-Madison in 2015. His research group works on [[phylogenomics]], [[evolutionary developmental biology]], and [[comparative genomics]] of ancient invertebrate groups, with emphasis on [[Chelicerata|chelicerate arthropods]]. He is the director of the Zoology Museum of the University of Wisconsin-Madison. He received a distinguished Class of 1955 Teaching Excellence Award.<ref>{{Cite web |last=Auger |first=Ian |date=2023-01-30 |title=UW awards Distinguished Teaching Awards to twelve faculty |url=https://badgerherald.com/news/2023/01/30/uw-awards-distinguished-teaching-awards-to-twelve-faculty |access-date=2023-05-09 |website=The Badger Herald}}</ref><ref>{{Cite web |title=Meet the 2023 Distinguished Teaching Award recipients |url=https://news.wisc.edu/meet-the-2023-distinguished-teaching-award-recipients-2/ |access-date=2023-05-09 |website=news.wisc.edu |language=en-US}}</ref>
+His early work focused on the systematics and biogeography of the armored harvestmen ([[Laniatores]]) from the South Pacific. In 2011, he described three new families of harvestmen from the Paleotropics and showed that one family of armored harvestmen is capable of extreme dispersal, in contrast to the rest of this arachnid order.<ref>{{Cite journal |date=2012-05 |title=Arachnids crossed the Pacific |url=http://www.nature.com/articles/485550a |journal=Nature |language=en |volume=485 |issue=7400 |pages=550–550 |doi=10.1038/485550a |issn=0028-0836}}</ref> His research group later discovered a suborder of fossil daddy-long-legs with four eyes called [[Tetrophthalmi|Tetraophthalmi]], whereas all living species only have two eyes.<ref>{{Cite web |last=Blaszczak-Boxe,LiveScience |first=Agata |title=Four-Eyed 'Daddy Longlegs' Fossil Discovered |url=https://www.scientificamerican.com/article/four-eyed-daddy-longlegs-fossil-discovered/ |access-date=2023-05-10 |website=Scientific American |language=en}}</ref><ref>{{Cite web |date=2014-04-11 |title=Daddy longlegs once had four eyes, research says |url=https://www.pbs.org/newshour/science/daddy-longlegs-four-eyes-research-says |access-date=2023-05-10 |website=PBS NewsHour |language=en-us}}</ref>
-His group is best known for using genome duplications to understand the relationships of [[arachnid]]s. He proposed a grouping of arachnids with book lungs as well as [[pseudoscorpion]]s, which is called "Arachnopulmonata" and is united by a shared whole genome duplication.<ref>{{Cite journal |last=Sharma |first=Prashant P. |last2=Kaluziak |first2=Stefan T. |last3=Pérez-Porro |first3=Alicia R. |last4=González |first4=Vanessa L. |last5=Hormiga |first5=Gustavo |last6=Wheeler |first6=Ward C. |last7=Giribet |first7=Gonzalo |date=November 2014 |title=Phylogenomic Interrogation of Arachnida Reveals Systemic Conflicts in Phylogenetic Signal |url=https://academic.oup.com/mbe/article-lookup/doi/10.1093/molbev/msu235 |journal=Molecular Biology and Evolution |language=en |volume=31 |issue=11 |pages=2963–2984 |doi=10.1093/molbev/msu235 |issn=1537-1719}}</ref><ref name=":0">{{Cite journal |last=Ballesteros |first=Jesús A |last2=Sharma |first2=Prashant P |date=2019-11-01 |editor-last=Halanych |editor-first=Ken |title=A Critical Appraisal of the Placement of Xiphosura (Chelicerata) with Account of Known Sources of Phylogenetic Error |url=https://academic.oup.com/sysbio/article/68/6/896/5319972 |journal=Systematic Biology |language=en |volume=68 |issue=6 |pages=896–917 |doi=10.1093/sysbio/syz011 |issn=1063-5157}}</ref><ref>{{Cite journal |last=Ontano |first=Andrew Z |last2=Gainett |first2=Guilherme |last3=Aharon |first3=Shlomi |last4=Ballesteros |first4=Jesús A |last5=Benavides |first5=Ligia R |last6=Corbett |first6=Kevin F |last7=Gavish-Regev |first7=Efrat |last8=Harvey |first8=Mark S |last9=Monsma |first9=Scott |last10=Santibáñez-López |first10=Carlos E |last11=Setton |first11=Emily V W |last12=Zehms |first12=Jakob T |last13=Zeh |first13=Jeanne A |last14=Zeh |first14=David W |last15=Sharma |first15=Prashant P |date=2021-05-19 |editor-last=Pupko |editor-first=Tal |title=Taxonomic Sampling and Rare Genomic Changes Overcome Long-Branch Attraction in the Phylogenetic Placement of Pseudoscorpions |url=https://academic.oup.com/mbe/article/38/6/2446/6132263 |journal=Molecular Biology and Evolution |language=en |volume=38 |issue=6 |pages=2446–2467 |doi=10.1093/molbev/msab038 |issn=1537-1719 |pmc=8136511 |pmid=33565584}}</ref><ref name=":1">{{Cite journal |last=Ballesteros |first=Jesús A |last2=Santibáñez-López |first2=Carlos E |last3=Baker |first3=Caitlin M |last4=Benavides |first4=Ligia R |last5=Cunha |first5=Tauana J |last6=Gainett |first6=Guilherme |last7=Ontano |first7=Andrew Z |last8=Setton |first8=Emily V W |last9=Arango |first9=Claudia P |last10=Gavish-Regev |first10=Efrat |last11=Harvey |first11=Mark S |last12=Wheeler |first12=Ward C |last13=Hormiga |first13=Gustavo |last14=Giribet |first14=Gonzalo |last15=Sharma |first15=Prashant P |date=2022-02-03 |editor-last=Teeling |editor-first=Emma |title=Comprehensive Species Sampling and Sophisticated Algorithmic Approaches Refute the Monophyly of Arachnida |url=https://academic.oup.com/mbe/article/doi/10.1093/molbev/msac021/6522129 |journal=Molecular Biology and Evolution |language=en |volume=39 |issue=2 |pages=msac021 |doi=10.1093/molbev/msac021 |issn=0737-4038 |pmc=8845124 |pmid=35137183}}</ref> He proposed that horseshoe crabs are part of Arachnida and that arachnids independently colonized land more than once,<ref>{{Cite news |last=Greenwood |first=Veronique |date=2022-02-18 |title=Act of ‘Heresy’ Adds Horseshoe Crabs to Arachnid Family Tree |language=en-US |work=The New York Times |url=https://www.nytimes.com/2022/02/18/science/horseshoe-crabs-arachnids.html |access-date=2023-05-09 |issn=0362-4331}}</ref> using both genomes and fossils.<ref name=":0" /><ref name=":1" />
+His group is best known for using genome duplications to understand the relationships of [[arachnid]]s. He proposed a grouping of arachnids with book lungs as well as [[pseudoscorpion]]s, which is called "Arachnopulmonata" and is united by a shared whole genome duplication.<ref>{{Cite journal |last=Sharma |first=Prashant P. |last2=Kaluziak |first2=Stefan T. |last3=Pérez-Porro |first3=Alicia R. |last4=González |first4=Vanessa L. |last5=Hormiga |first5=Gustavo |last6=Wheeler |first6=Ward C. |last7=Giribet |first7=Gonzalo |date=November 2014 |title=Phylogenomic Interrogation of Arachnida Reveals Systemic Conflicts in Phylogenetic Signal |url=https://academic.oup.com/mbe/article-lookup/doi/10.1093/molbev/msu235 |journal=Molecular Biology and Evolution |language=en |volume=31 |issue=11 |pages=2963–2984 |doi=10.1093/molbev/msu235 |issn=1537-1719}}</ref><ref name=":0">{{Cite journal |last=Ballesteros |first=Jesús A |last2=Sharma |first2=Prashant P |date=2019-11-01 |editor-last=Halanych |editor-first=Ken |title=A Critical Appraisal of the Placement of Xiphosura (Chelicerata) with Account of Known Sources of Phylogenetic Error |url=https://academic.oup.com/sysbio/article/68/6/896/5319972 |journal=Systematic Biology |language=en |volume=68 |issue=6 |pages=896–917 |doi=10.1093/sysbio/syz011 |issn=1063-5157}}</ref><ref>{{Cite journal |last=Ontano |first=Andrew Z |last2=Gainett |first2=Guilherme |last3=Aharon |first3=Shlomi |last4=Ballesteros |first4=Jesús A |last5=Benavides |first5=Ligia R |last6=Corbett |first6=Kevin F |last7=Gavish-Regev |first7=Efrat |last8=Harvey |first8=Mark S |last9=Monsma |first9=Scott |last10=Santibáñez-López |first10=Carlos E |last11=Setton |first11=Emily V W |last12=Zehms |first12=Jakob T |last13=Zeh |first13=Jeanne A |last14=Zeh |first14=David W |last15=Sharma |first15=Prashant P |date=2021-05-19 |editor-last=Pupko |editor-first=Tal |title=Taxonomic Sampling and Rare Genomic Changes Overcome Long-Branch Attraction in the Phylogenetic Placement of Pseudoscorpions |url=https://academic.oup.com/mbe/article/38/6/2446/6132263 |journal=Molecular Biology and Evolution |language=en |volume=38 |issue=6 |pages=2446–2467 |doi=10.1093/molbev/msab038 |issn=1537-1719 |pmc=8136511 |pmid=33565584}}</ref><ref name=":1">{{Cite journal |last=Ballesteros |first=Jesús A |last2=Santibáñez-López |first2=Carlos E |last3=Baker |first3=Caitlin M |last4=Benavides |first4=Ligia R |last5=Cunha |first5=Tauana J |last6=Gainett |first6=Guilherme |last7=Ontano |first7=Andrew Z |last8=Setton |first8=Emily V W |last9=Arango |first9=Claudia P |last10=Gavish-Regev |first10=Efrat |last11=Harvey |first11=Mark S |last12=Wheeler |first12=Ward C |last13=Hormiga |first13=Gustavo |last14=Giribet |first14=Gonzalo |last15=Sharma |first15=Prashant P |date=2022-02-03 |editor-last=Teeling |editor-first=Emma |title=Comprehensive Species Sampling and Sophisticated Algorithmic Approaches Refute the Monophyly of Arachnida |url=https://academic.oup.com/mbe/article/doi/10.1093/molbev/msac021/6522129 |journal=Molecular Biology and Evolution |language=en |volume=39 |issue=2 |pages=msac021 |doi=10.1093/molbev/msac021 |issn=0737-4038 |pmc=8845124 |pmid=35137183}}</ref> He proposed that [[Horseshoe crab|horseshoe crabs]] are part of Arachnida and that arachnids independently colonized land more than once,<ref>{{Cite news |last=Greenwood |first=Veronique |date=2022-02-18 |title=Act of ‘Heresy’ Adds Horseshoe Crabs to Arachnid Family Tree |language=en-US |work=The New York Times |url=https://www.nytimes.com/2022/02/18/science/horseshoe-crabs-arachnids.html |access-date=2023-05-09 |issn=0362-4331}}</ref> using both genomes and fossils.<ref name=":0" /><ref name=":1" />
-His laboratory works on the genetics and development of [[Opiliones|daddy-long-legs]] ([[Opiliones]] or "harvestmen"). In 2021, his group sequenced the first [[Opiliones]] genome and created "daddy-short-legs" using gene silencing to understand how daddy-long-legs make their long legs.<ref>{{Cite web |last=Wu |first=Katherine J. |date=2021-08-03 |title=You’ve Never Seen Legs Like These |url=https://www.theatlantic.com/science/archive/2021/08/harvestmen-legs/619655/ |access-date=2023-05-09 |website=The Atlantic |language=en}}</ref><ref>{{Cite journal |date=2021-08-05 |title=How the daddy-long-legs gets long legs |url=https://www.nature.com/articles/d41586-021-02127-z |journal=Nature |language=en |volume=596 |issue=7871 |pages=167–167 |doi=10.1038/d41586-021-02127-z}}</ref>
+His laboratory works on the genetics and development of [[Opiliones|daddy-long-legs]] ([[Opiliones]] or "harvestmen") and [[Spider|spiders]]. He previously showed that spiders recycled leg-patterning genes to make the segments of their heads, an example of an evolutionary process called [[Co-option (biology)|cooption]].<ref>{{Cite web |date=2018-03-27 |title=Leg genes give spiders segmented heads |url=https://cosmosmagazine.com/nature/animals/leg-genes-give-spiders-segmented-heads/ |access-date=2023-05-10 |website=cosmosmagazine.com |language=en-AU}}</ref><ref>{{Cite journal |last=Setton |first=Emily V. W. |last2=Sharma |first2=Prashant P. |date=2018-04-10 |title=Cooption of an appendage-patterning gene cassette in the head segmentation of arachnids |url=https://pnas.org/doi/full/10.1073/pnas.1720193115 |journal=Proceedings of the National Academy of Sciences |language=en |volume=115 |issue=15 |doi=10.1073/pnas.1720193115 |issn=0027-8424 |pmc=PMC5899462 |pmid=29581309}}</ref> His team later showed that a gene duplicate restricted to Arachnopulmonata is responsible for making all eye types of spiders.<ref>{{Cite journal |last=Gainett |first=Guilherme |last2=Ballesteros |first2=Jesús A. |last3=Kanzler |first3=Charlotte R. |last4=Zehms |first4=Jakob T. |last5=Zern |first5=John M. |last6=Aharon |first6=Shlomi |last7=Gavish-Regev |first7=Efrat |last8=Sharma |first8=Prashant P. |date=2020-12 |title=Systemic paralogy and function of retinal determination network homologs in arachnids |url=https://bmcgenomics.biomedcentral.com/articles/10.1186/s12864-020-07149-x |journal=BMC Genomics |language=en |volume=21 |issue=1 |pages=811 |doi=10.1186/s12864-020-07149-x |issn=1471-2164}}</ref> In 2021, his group sequenced the first [[Opiliones]] genome and created "daddy-short-legs" using gene silencing to understand how daddy-long-legs make their long legs.<ref>{{Cite web |last=Wu |first=Katherine J. |date=2021-08-03 |title=You’ve Never Seen Legs Like These |url=https://www.theatlantic.com/science/archive/2021/08/harvestmen-legs/619655/ |access-date=2023-05-09 |website=The Atlantic |language=en}}</ref><ref>{{Cite journal |date=2021-08-05 |title=How the daddy-long-legs gets long legs |url=https://www.nature.com/articles/d41586-021-02127-z |journal=Nature |language=en |volume=596 |issue=7871 |pages=167–167 |doi=10.1038/d41586-021-02127-z}}</ref>
 ==References==
 {{Reflist}}
+== External links ==
-{{Uncategorized|date=May 2023}}
+[https://integrativebiology.wisc.edu/staff/sharma-prashant/ Prashant Sharma]: University of Wisconsin-Madison faculty page
+[https://scholar.google.com/citations?user=q6CI9VcAAAAJ&hl=en&authuser=1 Prashant P. Sharma] publications indexed by Google Scholar{{Uncategorized|date=May 2023}}