Precision cut lung slices: Difference between revisions
Content deleted Content added
Created new article Tags: Mobile edit Mobile web edit Advanced mobile edit |
(No difference)
|
Revision as of 13:50, 12 October 2023
Precision cut lung slices or PCLS refer to thin sections of lung tissue that are prepared with high precision and are typically used for experimental purposes in the field of respiratory research.[1] These slices are utilized to study various aspects of lung physiology, pathology, and pharmacology, providing researchers with a valuable tool for investigating lung diseases and testing the effects of drugs on lung tissue.[2]
Precision cut lung slices are prepared using specialized equipment called Compresstome vibratomes, ensuring that the tissue remains viable and retains its structural and functional characteristics, making them ideal for a wide range of experimental applications.[3][4]
- ^ Morin, Jean-Paul; Baste, Jean-Marc; Gay, Arnaud; Crochemore, Clément; Corbière, Cécile; Monteil, Christelle (2013). "Precision cut lung slices as an efficient tool for in vitro lung physio-pharmacotoxicology studies". Xenobiotica. 43 (1): 63–72. doi:10.3109/00498254.2012.727043. PMID 23030793. S2CID 207427454.
- ^ Liu, Yan; Wu, Ping; Wang, Yin; Liu, Yansong; Yang, Hongfang; Zhou, Guohua; Wu, Xiaoqi; Wen, Qingping (2022). "Application of Precision-Cut Lung Slices as an in Vitro Model for Research of Inflammatory Respiratory Diseases". Bioengineering. 9 (12): 767. doi:10.3390/bioengineering9120767. PMC 9774555. PMID 36550973.
- ^ Sewald, K.; Braun, A. (2013). "Assessment of immunotoxicity using precision-cut tissue slices". Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 43 (1): 84–97. doi:10.3109/00498254.2012.731543. PMC 3518294. PMID 23199366.
- ^ Abdelaal, H. M.; Kim, H. O.; Wagstaff R; Sawahata, R.; Southern, P. J.; Skinner, P. J. (2015). "Comparison of Vibratome and Compresstome sectioning of fresh primate lymphoid and genital tissues for in situ MHC-tetramer and immunofluorescence staining". Biological Procedures Online. 17 (1): 2. doi:10.1186/s12575-014-0012-4. PMC 4318225. PMID 25657614.