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Halobetasol/tazarotene
Combination of
Ulobetasol propionateCorticosteroid
TazaroteneRetinoid
Clinical data
Trade namesDuobrii
AHFS/Drugs.comMultum Consumer Information
Routes of
administration
Topical
Legal status
Legal status

Halobetasol/tazarotene (Duobrii) is a topical combination drug containing a corticosteroid and a retinoid. It combines 0.01% halobetasol propionate and 0.045% tazarotene in a lotion formulation.[1][2][3] It was approved as a prescription drug for treating plaque psoriasis in adults by the U.S. Food and Drug Administration in April 2019.[2][3][4]

References

  1. ^ "DUOBRII- halobetasol propionate and tazarotene lotion". DailyMed. 1 January 2020. Retrieved 15 January 2024.
  2. ^ a b Reddy V, Myers B, Yang EJ, Bhutani T (2020). "Impact of Halobetasol Propionate and Tazarotene Lotion 0.01%/0.045% in the Management of Plaque Psoriasis in Adults". Clinical, Cosmetic and Investigational Dermatology. 13: 391–398. doi:10.2147/CCID.S252426. PMC 7295208. PMID 32606876.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  3. ^ a b Tanghetti EA, Stein Gold L, Del Rosso JQ, Lin T, Angel A, Pillai R (June 2021). "Optimized formulation for topical application of a fixed combination halobetasol/tazarotene lotion using polymeric emulsion technology". The Journal of Dermatological Treatment. 32 (4): 391–398. doi:10.1080/09546634.2019.1668907. PMID 31522563.
  4. ^ Duffy, Steve (26 April 2019). "FDA Approves Unique Combination Topical Therapy for Plaque Psoriasis". MPR. Retrieved 16 January 2024.