DDX1

DDX1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4XW3
Identifiers
Aliases	DDX1, DBP-RB, UKVH5d, DEAD/H-box helicase 1, DEAD-box helicase 1
External IDs	OMIM: 601257; MGI: 2144727; HomoloGene: 3627; GeneCards: DDX1; OMA:DDX1 - orthologs
Gene location (Human) Chr. Chromosome 2 (human) Band 2p24.3 Start 15,591,178 bp End 15,634,346 bp
Gene location (Mouse) Chr. Chromosome 12 (mouse) Band 12|12 A1.1 Start 13,266,974 bp End 13,299,214 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right ventricle deltoid muscle triceps brachii muscle middle temporal gyrus parotid gland islet of Langerhans gastrocnemius muscle tibialis anterior muscle ganglionic eminence quadriceps femoris muscle Top expressed in primitive streak spermatid spermatocyte maxillary prominence triceps brachii muscle temporal muscle hair follicle facial motor nucleus medial ganglionic eminence sternocleidomastoid muscle More reference expression data BioGPS More reference expression data
Gene ontology Molecular function RNA helicase activity DNA binding nucleotide binding helicase activity poly(A) binding chromatin binding transcription coregulator activity DNA/RNA helicase activity protein binding nucleic acid binding nuclease activity double-stranded RNA binding exonuclease activity hydrolase activity ATP binding RNA binding Cellular component cytoplasm membrane nucleoplasm tRNA-splicing ligase complex cytoplasmic stress granule cleavage body nucleus cytosol nucleolus mitochondrion ribonucleoprotein complex Biological process regulation of transcription, DNA-templated response to exogenous dsRNA mRNA processing response to virus protein localization to cytoplasmic stress granule transcription, DNA-templated multicellular organism development spliceosomal complex assembly DNA duplex unwinding double-strand break repair RNA secondary structure unwinding regulation of translational initiation tRNA splicing, via endonucleolytic cleavage and ligation tRNA processing nucleic acid phosphodiester bond hydrolysis immune system process positive regulation of myeloid dendritic cell cytokine production positive regulation of I-kappaB kinase/NF-kappaB signaling innate immune response defense response to virus regulation of nucleic acid-templated transcription Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 1653 104721 Ensembl ENSG00000079785 ENSMUSG00000037149 UniProt Q92499 Q91VR5 RefSeq (mRNA) NM_004939 NM_134040 RefSeq (protein) NP_004930 NP_598801 Location (UCSC) Chr 2: 15.59 – 15.63 Mb Chr 12: 13.27 – 13.3 Mb PubMed search
Wikidata
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DEAD (Asp-Glu-Ala-Asp) box polypeptide 1, also known as DDX1, is a human gene.