Small nucleolar RNA SNORA73: Difference between revisions
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{{Rfam_box|acc=RF00045|description=Small nucleolar RNA SNORA73|abbreviation=SNORA73|type=Gene; snRNA; guide; HACA-box;|avg_length=207.7|avg_identity=71|ss=Published; {{PMID|11821910}}|se=Griffiths-Jones SR; Cervelli et al, {{PMID|11821910}}|type=Gene; snRNA; guide; HACA-box;}} |
{{Rfam_box|acc=RF00045|description=Small nucleolar RNA SNORA73|abbreviation=SNORA73|type=Gene; snRNA; guide; HACA-box;|avg_length=207.7|avg_identity=71|ss=Published; {{PMID|11821910}}|se=Griffiths-Jones SR; Cervelli et al, {{PMID|11821910}}|type=Gene; snRNA; guide; HACA-box;}} |
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In [[molecular biology]], the '''small nucleolar RNA SNORA73''' (also called '''U17/E1 RNA''') belongs to the H/ACA class of [[small nucleolar RNA]]s (snoRNAs). Vertebrate U17 is [[intron]]-encoded and ranges in length from 200-230 [[nucleotide]]s, longer than most snoRNAs. It is one of the most abundant snoRNAs in [[human cell]]s and is essential for the cleavage of pre-[[rRNA]] within the 5' external transcribed spacer (ETS).<ref>{{cite journal | last = Enright | first = CA | coauthors = Maxwell ES, Eliceiri GL, Sollner-Webb B | year = 1996 | title = 5'ETS rRNA processing facilitated by four small RNAs: U14, E3, U17, and U3 | journal = RNA | volume = 2 | pages = 1094–1099 | |
In [[molecular biology]], the '''small nucleolar RNA SNORA73''' (also called '''U17/E1 RNA''') belongs to the H/ACA class of [[small nucleolar RNA]]s (snoRNAs). Vertebrate U17 is [[intron]]-encoded and ranges in length from 200-230 [[nucleotide]]s, longer than most snoRNAs. It is one of the most abundant snoRNAs in [[human cell]]s and is essential for the cleavage of pre-[[rRNA]] within the 5' external transcribed spacer (ETS).<ref>{{cite journal | last = Enright | first = CA | coauthors = Maxwell ES, Eliceiri GL, Sollner-Webb B | year = 1996 | title = 5'ETS rRNA processing facilitated by four small RNAs: U14, E3, U17, and U3 | journal = RNA | volume = 2 | pages = 1094–1099 | pmid = 8903340}}</ref> This cleavage leads to the formation of 18S rRNA. Regions of the U17 RNA are complementary to rRNA and act as guides for RNA/RNA interactions, although these regions do not seem to be well conserved between organisms.<ref>{{cite journal | last = Cervelli | first = M | coauthors = Cecconi F, Giorgi M, Annesi F, Oliverio M, Mariottini P | year = 2002 | title = Comparative Structure Analysis of Vertebrate U17 Small Nucleolar RNA (snoRNA) | journal = J Mol Evol | volume = 54 | pages = 166–179 | pmid = 11821910 | doi = 10.1007/s00239-001-0065-2}}</ref> |
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==References== |
==References== |
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Revision as of 13:59, 8 June 2008
| Small nucleolar RNA SNORA73 | |
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| PDB structures | PDBe |
In molecular biology, the small nucleolar RNA SNORA73 (also called U17/E1 RNA) belongs to the H/ACA class of small nucleolar RNAs (snoRNAs). Vertebrate U17 is intron-encoded and ranges in length from 200-230 nucleotides, longer than most snoRNAs. It is one of the most abundant snoRNAs in human cells and is essential for the cleavage of pre-rRNA within the 5' external transcribed spacer (ETS).[1] This cleavage leads to the formation of 18S rRNA. Regions of the U17 RNA are complementary to rRNA and act as guides for RNA/RNA interactions, although these regions do not seem to be well conserved between organisms.[2]
References
- ^ Enright, CA (1996). "5'ETS rRNA processing facilitated by four small RNAs: U14, E3, U17, and U3". RNA. 2: 1094–1099. PMID 8903340.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help) - ^ Cervelli, M (2002). "Comparative Structure Analysis of Vertebrate U17 Small Nucleolar RNA (snoRNA)". J Mol Evol. 54: 166–179. doi:10.1007/s00239-001-0065-2. PMID 11821910.
{{cite journal}}: Unknown parameter|coauthors=ignored (|author=suggested) (help)
External links
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