ORFeome: Difference between revisions

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* ''Escherichia coli''<ref name="EcoliORFeome">{{Cite pmid| 20701780}}</ref>
* ''Escherichia coli''<ref name="EcoliORFeome">{{Cite pmid| 20701780}}</ref>
* ''Brucella melitensis''<ref name="BmeORFeome">{{Cite pmid| 19524659}}</ref>
* ''Brucella melitensis''<ref name="BmeORFeome">{{Cite pmid| 19524659}}</ref>
* ''Chlamydia pneumoniae''<ref name="CpnORFeome">{{Cite pmid| 23157390}}</ref>
* ''Staphylococcus aureus''<ref name="SauORFeome">{{Cite pmid| 18605992}}</ref>
* ''Staphylococcus aureus''<ref name="SauORFeome">{{Cite pmid| 18605992}}</ref>
* human herpesviruses<ref name="herpesORFeome">{{Cite pmid| 19730696}}</ref>
* human herpesviruses<ref name="herpesORFeome">{{Cite pmid| 19730696}}</ref>

Revision as of 21:32, 7 December 2012

Orfeome is the complete set of open reading frames (ORF) that exists in a genome. More specifically, ORFeome refers to a set of cloned ORFs.[1] ORFs correspond to the coding sequences (CDS) of genes. ORFs can be found in genome sequences by computer programs such as GENSCAN. While this is relatively trivial in bacteria the problem is non-trivial in eukaryotic genomes because of the presence of introns and exons. The usage of complete ORFeomes reflects a new trend in biology that can be succinctly summarized as omics. For instance, ORFeomes are used for the study of protein-protein interactions.[2][3]

Cloned ORFeomes

Complete ORF sets have been cloned for a number of organisms including

  • Escherichia coli[4]
  • Brucella melitensis[5]
  • Chlamydia pneumoniae[6]
  • Staphylococcus aureus[7]
  • human herpesviruses[8]

References

  1. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 19718504, please use {{cite journal}} with |pmid= 19718504 instead.
  2. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 18509523, please use {{cite journal}} with |pmid= 18509523 instead.
  3. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 15489322, please use {{cite journal}} with |pmid= 15489322 instead.
  4. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 20701780, please use {{cite journal}} with |pmid= 20701780 instead.
  5. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 19524659, please use {{cite journal}} with |pmid= 19524659 instead.
  6. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 23157390, please use {{cite journal}} with |pmid= 23157390 instead.
  7. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 18605992, please use {{cite journal}} with |pmid= 18605992 instead.
  8. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 19730696, please use {{cite journal}} with |pmid= 19730696 instead.