Pyrobaculum asR3 small RNA: Difference between revisions

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asR3 is an archeal small RNA identified in seven Pyrobaculum species. The geneus-specific nature can indicate this could be recent, stable adaptation.[1] asR3 binds to the 3'-end of the tpi gene (triose-phosphate-isomerse)[2]. The tpi mRNA has a conserved structural element located close to the stop codon. Binding of the asR3 may be able to compete agains the formation of the tpi element structure and this may modulate the function of this highly conserved element.[1]


References

  1. ^ a b Bernick, David L.; Dennis, Patrick P.; Lui, Lauren M.; Lowe, Todd M. (2012). "Diversity of Antisense and Other Non-Coding RNAs in Archaea Revealed by Comparative Small RNA Sequencing in Four Pyrobaculum Species". Frontiers in Microbiology. 3: 231. doi:10.3389/fmicb.2012.00231. ISSN 1664-302X. PMC 3388794. PMID 22783241.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)
  2. ^ Alber, T.; Banner, D. W.; Bloomer, A. C.; Petsko, G. A.; Phillips, D.; Rivers, P. S.; Wilson, I. A. (1981-06-26). "On the three-dimensional structure and catalytic mechanism of triose phosphate isomerase". Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 293 (1063): 159โ€“171. ISSN 0962-8436. PMID 6115415.