Hepatitis B virus PRE 1151–1410: Difference between revisions
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Hepatitis B virus PRE 1151-1410 (HBV post-transcriptional regulatory element, nucleotides 1151-1410) is a part of 500 base pair long HBV PRE, that has been proposed to be the HBV RNA export element.[1] [2][3] However, the function is controversial and new regulatory elements have been predicted within PRE.[4] PRE 1151-1410 enhances nuclear export of intronless transcripts and represses the splicing mechanism to a comparable degree to that of the full-length PRE. Hence it was proposed to be the a core HBV PRE element.[5]
See also
References
- ^ Panjaworayan, Nattanan; Roessner, Stephan K.; Firth, Andrew E.; Brown, Chris M. (2007-12-17). "HBVRegDB: annotation, comparison, detection and visualization of regulatory elements in hepatitis B virus sequences". Virology Journal. 4: 136. doi:10.1186/1743-422X-4-136. ISSN 1743-422X. PMC 2235840. PMID 18086305.
{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link) - ^ Huang, J.; Liang, T. J. (December 1993). "A novel hepatitis B virus (HBV) genetic element with Rev response element-like properties that is essential for expression of HBV gene products". Molecular and Cellular Biology. 13 (12): 7476–7486. ISSN 0270-7306. PMID 8246965.
- ^ Huang, Z. M.; Yen, T. S. (May 1994). "Hepatitis B virus RNA element that facilitates accumulation of surface gene transcripts in the cytoplasm". Journal of Virology. 68 (5): 3193–3199. ISSN 0022-538X. PMID 8151782.
- ^ Visootsat, Akasit; Payungporn, Sunchai; T-Thienprasert, Nattanan P. (December 2015). "A conserved RNA structural element within the hepatitis B virus post-transcriptional regulatory element enhance nuclear export of intronless transcripts and repress the splicing mechanism". Molecular Biology Reports. 42 (12): 1603–1614. doi:10.1007/s11033-015-3928-0. ISSN 1573-4978. PMID 26514143.
- ^ Visootsat, Akasit; Payungporn, Sunchai; T-Thienprasert, Nattanan P. (December 2015). "A conserved RNA structural element within the hepatitis B virus post-transcriptional regulatory element enhance nuclear export of intronless transcripts and repress the splicing mechanism". Molecular Biology Reports. 42 (12): 1603–1614. doi:10.1007/s11033-015-3928-0. ISSN 1573-4978. PMID 26514143.
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