Joachim Boldt: Difference between revisions
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As of 2017, 96 of his papers have been retracted.<ref>http://retractionwatch.com/the-retraction-watch-leaderboard/</ref> |
As of 2017, 96 of his papers have been retracted.<ref>http://retractionwatch.com/the-retraction-watch-leaderboard/</ref> |
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In October 2018 a review highlighted additional retractions, the first fraudulent one retracted was from 1986 demonstrating persistent fraud for the entire career of Boldt ,Statistical analyses demonstrate,that still many most likely fraudulent papers from Boldt are out there and editors should take action. |
In October 2018 a review highlighted additional retractions, the first fraudulent one retracted was from 1986 demonstrating persistent fraud for the entire career of Boldt ,Statistical analyses demonstrate,that still many most likely fraudulent papers from Boldt are out there and editors should take action.<ref>{{cite journal |doi=10.1007/s00134-018-5289-3 }}</ref> |
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https://www.ncbi.nlm.nih.gov/pubmed/29968012 |
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reference Wiedermann CJ and Ioannidis, M Int. Care Med. 2018 ,Oct 44 pp1735-1737 The Boldt scandal still in need of action: the example of colloids 10 years after initial suspicion of fraud. |
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== See also == |
== See also == |
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* [[List of scientific misconduct incidents]] |
* [[List of scientific misconduct incidents]] |
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Revision as of 23:11, 27 November 2018
 | This article needs to be updated. (December 2017) |
Joachim Boldt (born September 29, 1954[1]) is a German anesthesiologist who was previously considered a leading researcher into colloids. He has been stripped of his professorship and is under criminal investigation for possible forgery of up to 90 research studies.[2]
The editors of 16 different scientific journals, including Anesthesia & Analgesia, Anaesthesia, the European Journal of Anaesthesiology and the British Journal of Anaesthesia, allege that 89 of 102 studies published by Boldt contained research without proper institutional review board approval.[3]
On November 10, 2010, Boldt was suspended from Klinikum Ludwigshafen, a hospital in Germany, for a scientific publication in Anesthesia & Analgesia with insufficient background research. His field of research and the publications were related to hydroxyethyl starch (HES).[4] Some 90 studies he published are currently being reviewed by medical authorities.[5]
In February 2011, Boldt was stripped of his title of professor at the University of Giessen for failing to teach, and the university is investigating possible charges of scientific misconduct.[6] His case was described at the time as "possibly the biggest medical research scandal since Andrew Wakefield was struck off in 2010 for falsely claiming to have proved a link between the MMR vaccine and autism".[2]
In August 2012, the hospital released the results of its investigation: while no patients were harmed, "in a large number of the studies investigated, the conduct of research failed to meet required standards. False data were published in at least 10 of the 91 articles examined, including, for instance, data on patient numbers/ study groups as well as data on the timing of measurements".[7]
On February 20, 2013, JAMA published a metaanalysis on HES in critically ill patients (Zachyranski R et al.)[8] Boldt had 7 studies from the 1990s that had not yet been retracted. Including them, there was no increase in mortality, but excluding them, there was a significant increase in mortality. Only the Boldt studies showed an improvement with HES; all other studies showed the opposite. It is believed that his fraudulent studies put critically ill patients at risk and caused harm.[9]
An overview of the challenges for meta-analysts presented by the fraud has recently been published. It includes double publication of studies, manipulating demographic and outcome data to conceal double publication and getting better results for a drug being tested.[10]
As of 2017, 96 of his papers have been retracted.[11] In October 2018 a review highlighted additional retractions, the first fraudulent one retracted was from 1986 demonstrating persistent fraud for the entire career of Boldt ,Statistical analyses demonstrate,that still many most likely fraudulent papers from Boldt are out there and editors should take action.[12]
See also
References
- ^ "Archived copy" (PDF). Archived from the original (PDF) on 2012-03-19. Retrieved 2011-03-11.
{{cite web}}: Unknown parameter|deadurl=ignored (|url-status=suggested) (help)CS1 maint: archived copy as title (link) - ^ a b Heidi Blake, Holly Watt and Robert Winnett. "Millions of surgery patients at risk in drug research fraud scandal". The Telegraph, 03 Mar 2011 (retrieved 2011-03-03)
- ^ "Medical journals retract 'unethical' research", Kate Kelland, Reuters, March 4, 2011
- ^ Informationsdienst Wissenschaf: "DGAI: Wissenschaftliches Fehlverhalten in der Anästhesie inakzeptabel" 2010-11-26 (retrieved 2011-03-04) German
- ^ "Joachim Boldt profile: a glittering career built on charisma and charm", Daily Telegraph, 2011-03-03 (retrieved: 2011-03-04)
- ^ Giessen University: "Akademische Bezeichnung aberkannt" 2011-02-15 (retrieved: 2011-03-04) Template:De icon
- ^ Press release, Klinikum Ludwigshafen, http://www.klilu.de/content/aktuelles___presse/pressearchiv/2012/hospital_presents_results_of_final_report_committee_completes_investigation_in_the_case_of_dr_boldt/index_ger.html, 9 August 2012
- ^ http://jama.jamanetwork.com/article.aspx?articleid=1653505
- ^ JAMA by Antonelli, Editor of Int Care Medicine.http://jama.jamanetwork.com/article.aspx?articleid=1653508
- ^ http://www.anesthesiologynews.com/ViewArticle.aspx?d=Commentary&d_id=449&i=April+2013&i_id=945&a_id=22877
- ^ http://retractionwatch.com/the-retraction-watch-leaderboard/
- ^ . doi:10.1007/s00134-018-5289-3.
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