Andrew Kasarskis: Difference between revisions

Edit links
From Wikipedia, the free encyclopedia
Browse history interactively
← Previous editNext edit →
Content deleted Content added
VisualWikitext
m Add Top 2 Publications to Pathogens sections and top 2 publications to complex disease section. Also, changed name of sleep section to pathogen disease section. Added latest research to career and research section.
Line 26: Line 26:


Kasarskis has called for improvements to informed consent protocols in patient research based on the concept that studies involving DNA cannot fully be made anonymous. He was quoted in the journal Nature saying, “We need to move beyond an assumption that you cannot be identified from the data that exist about you and really work to make sure that we’re protecting people’s rights in ways that allow us to use the data that are out there for individuals’ and researchers’ benefit.”<ref>{{cite journal |url=http://www.nature.com/news/open-data-project-aims-to-ease-the-way-for-genomic-research-1.10507 |title=Open-data project aims to ease the way for genomic research |journal=Nature News |publisher=Nature.com |date=2012-04-25 |accessdate=2013-06-10|doi=10.1038/nature.2012.10507 |last1=Check Hayden |first1=Erika }}</ref>
Kasarskis has called for improvements to informed consent protocols in patient research based on the concept that studies involving DNA cannot fully be made anonymous. He was quoted in the journal Nature saying, “We need to move beyond an assumption that you cannot be identified from the data that exist about you and really work to make sure that we’re protecting people’s rights in ways that allow us to use the data that are out there for individuals’ and researchers’ benefit.”<ref>{{cite journal |url=http://www.nature.com/news/open-data-project-aims-to-ease-the-way-for-genomic-research-1.10507 |title=Open-data project aims to ease the way for genomic research |journal=Nature News |publisher=Nature.com |date=2012-04-25 |accessdate=2013-06-10|doi=10.1038/nature.2012.10507 |last1=Check Hayden |first1=Erika }}</ref>

Kasarskis's latest research focuses on [https://www.mountsinai.org/about/newsroom/2018/sanofi-sema4-mount-sinai-collaborate-on-largest-asthma-study-of-its-kind asthma] and [https://www.genomeweb.com/informatics/qa-mount-sinai-chief-data-officer-andrew-kasarskis-his-new-role#.XS4p3pNKgkg clinical data infrastructures.] In his new role as [https://www.mountsinai.org/about/newsroom/2019/mount-sinai-accelerates-datadriven-discovery-and-patient-care-with-new-chief-data-officer-rolehttps://www.mountsinai.org/about/newsroom/2019/mount-sinai-accelerates-datadriven-discovery-and-patient-care-with-new-chief-data-officer-role Chief Data Officer of Mount Sinai Health System] and [https://www.beckershospitalreview.com/hospital-executive-moves/mount-sinai-health-system-selects-first-chief-data-officer-6-things-to-know.html Executive Vice President] Andrew is evaluating Mount Sinai's biomedical data and how the data can be used to advance patient outcomes.


== Selected publications ==
== Selected publications ==
Line 37: Line 39:
=== Pathogens ===
=== Pathogens ===


* Genomic Surveillance Reveals Diversity of Multidrug-Resistant Organism Colonization and Infection: A Prospective Cohort Study in Liver Transplant Recipients Nenad Macesic, Angela Gomez-Simmonds, Sean B Sullivan, Marla J Giddins, Samantha A Ferguson, Gautam Korakavi, David Leeds, Sarah Park, Kevin Shim, Madeleine G Sowash, Melanie Hofbauer, Ryan Finkel, Yue Hu, Jared West, Nora C Toussaint, William G Greendyke, Benjamin A Miko, Marcus R Pereira, Susan Whittier, Elizabeth C Verna, Anne-Catrin Uhlemann Clin Infect Dis. 2018 Sep 15; 67(6): 905–912. Published online 2018 Apr 28. doi: 10.1093/cid/ciy199<ref>{{Cite journal|last=Pak|first=Theodore R.|last2=Kasarskis|first2=Andrew|date=2015-12-01|title=How next-generation sequencing and multiscale data analysis will transform infectious disease management|url=https://www.ncbi.nlm.nih.gov/pubmed/26251049|journal=Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America|volume=61|issue=11|pages=1695–1702|doi=10.1093/cid/civ670|issn=1537-6591|pmc=4643486|pmid=26251049}}</ref>
* {{Cite journal |doi = 10.1038/nbt.2288|pmid = 22750883|pmc = 3731737|title = A hybrid approach for the automated finishing of bacterial genomes|journal = Nature Biotechnology|volume = 30|issue = 7|pages = 701–707|year = 2012|last1 = Bashir|first1 = Ali|last2 = Klammer|first2 = Aaron A.|last3 = Robins|first3 = William P.|last4 = Chin|first4 = Chen-Shan|last5 = Webster|first5 = Dale|last6 = Paxinos|first6 = Ellen|last7 = Hsu|first7 = David|last8 = Ashby|first8 = Meredith|last9 = Wang|first9 = Susana|last10 = Peluso|first10 = Paul|last11 = Sebra|first11 = Robert|last12 = Sorenson|first12 = Jon|last13 = Bullard|first13 = James|last14 = Yen|first14 = Jackie|last15 = Valdovino|first15 = Marie|last16 = Mollova|first16 = Emilia|last17 = Luong|first17 = Khai|last18 = Lin|first18 = Steven|last19 = Lamay|first19 = Brianna|last20 = Joshi|first20 = Amruta|last21 = Rowe|first21 = Lori|last22 = Frace|first22 = Michael|last23 = Tarr|first23 = Cheryl L.|last24 = Turnsek|first24 = Maryann|last25 = Davis|first25 = Brigid M.|last26 = Kasarskis|first26 = Andrew|last27 = Mekalanos|first27 = John J.|last28 = Waldor|first28 = Matthew K.|last29 = Schadt|first29 = Eric E.}}
*Pak TR, Chacko KI, O'Donnell T, Huprikar SS, van Bakel H, Kasarskis A, Scott ER. Estimating Local Costs Associated With Clostridium difficile Infection Using Machine Learning and Electronic Medical Records. ''Infect Control Hosp Epidemiol''. 2017 Dec;38(12):1478-1486. doi: 10.1017/ice.2017.214. Epub 2017 Nov 6. PubMed PMID: 29103378; PubMed Central PMCID: PMC5923033.<ref>{{Cite journal|last=Pak|first=Theodore R.|last2=Chacko|first2=Kieran I.|last3=O'Donnell|first3=Timothy|last4=Huprikar|first4=Shirish S.|last5=van Bakel|first5=Harm|last6=Kasarskis|first6=Andrew|last7=Scott|first7=Erick R.|date=12 2017|title=Estimating Local Costs Associated With Clostridium difficile Infection Using Machine Learning and Electronic Medical Records|url=https://www.ncbi.nlm.nih.gov/pubmed/29103378|journal=Infection Control and Hospital Epidemiology|volume=38|issue=12|pages=1478–1486|doi=10.1017/ice.2017.214|issn=1559-6834|pmc=5923033|pmid=29103378}}</ref>
* {{cite journal|title=Origins of the E. coli Strain Causing an Outbreak of Hemolytic–Uremic Syndrome in Germany |journal=New England Journal of Medicine |volume=365 |issue=8 |pages=709–717 |doi=10.1056/NEJMoa1106920 |pmid=21793740 |pmc=3168948 |year=2011 |last1=Rasko |first1=David A. |last2=Webster |first2=Dale R. |last3=Sahl |first3=Jason W. |last4=Bashir |first4=Ali |last5=Boisen |first5=Nadia |last6=Scheutz |first6=Flemming |last7=Paxinos |first7=Ellen E. |last8=Sebra |first8=Robert |last9=Chin |first9=Chen-Shan |last10=Iliopoulos |first10=Dimitris |last11=Klammer |first11=Aaron |last12=Peluso |first12=Paul |last13=Lee |first13=Lawrence |last14=Kislyuk |first14=Andrey O. |last15=Bullard |first15=James |last16=Kasarskis |first16=Andrew |last17=Wang |first17=Susanna |last18=Eid |first18=John |last19=Rank |first19=David |last20=Redman |first20=Julia C. |last21=Steyert |first21=Susan R. |last22=Frimodt-Møller |first22=Jakob |last23=Struve |first23=Carsten |last24=Petersen |first24=Andreas M. |last25=Krogfelt |first25=Karen A. |last26=Nataro |first26=James P. |last27=Schadt |first27=Eric E. |last28=Waldor |first28=Matthew K. }}
* {{cite journal|title=Origins of the E. coli Strain Causing an Outbreak of Hemolytic–Uremic Syndrome in Germany |journal=New England Journal of Medicine |volume=365 |issue=8 |pages=709–717 |doi=10.1056/NEJMoa1106920 |pmid=21793740 |pmc=3168948 |year=2011 |last1=Rasko |first1=David A. |last2=Webster |first2=Dale R. |last3=Sahl |first3=Jason W. |last4=Bashir |first4=Ali |last5=Boisen |first5=Nadia |last6=Scheutz |first6=Flemming |last7=Paxinos |first7=Ellen E. |last8=Sebra |first8=Robert |last9=Chin |first9=Chen-Shan |last10=Iliopoulos |first10=Dimitris |last11=Klammer |first11=Aaron |last12=Peluso |first12=Paul |last13=Lee |first13=Lawrence |last14=Kislyuk |first14=Andrey O. |last15=Bullard |first15=James |last16=Kasarskis |first16=Andrew |last17=Wang |first17=Susanna |last18=Eid |first18=John |last19=Rank |first19=David |last20=Redman |first20=Julia C. |last21=Steyert |first21=Susan R. |last22=Frimodt-Møller |first22=Jakob |last23=Struve |first23=Carsten |last24=Petersen |first24=Andreas M. |last25=Krogfelt |first25=Karen A. |last26=Nataro |first26=James P. |last27=Schadt |first27=Eric E. |last28=Waldor |first28=Matthew K. }}
* {{cite journal|title=The origin of the Haitian cholera outbreak strain |journal=New England Journal of Medicine |volume=364 |issue=1 |pages=33–42 |doi=10.1056/NEJMoa1012928 |pmid=21142692 |pmc=3030187 |year=2011 |last1=Chin |first1=Chen-Shan |last2=Sorenson |first2=Jon |last3=Harris |first3=Jason B. |last4=Robins |first4=William P. |last5=Charles |first5=Richelle C. |last6=Jean-Charles |first6=Roger R. |last7=Bullard |first7=James |last8=Webster |first8=Dale R. |last9=Kasarskis |first9=Andrew |last10=Peluso |first10=Paul |last11=Paxinos |first11=Ellen E. |last12=Yamaichi |first12=Yoshiharu |last13=Calderwood |first13=Stephen B. |last14=Mekalanos |first14=John J. |last15=Schadt |first15=Eric E. |last16=Waldor |first16=Matthew K. }}
* {{cite journal|title=The origin of the Haitian cholera outbreak strain |journal=New England Journal of Medicine |volume=364 |issue=1 |pages=33–42 |doi=10.1056/NEJMoa1012928 |pmid=21142692 |pmc=3030187 |year=2011 |last1=Chin |first1=Chen-Shan |last2=Sorenson |first2=Jon |last3=Harris |first3=Jason B. |last4=Robins |first4=William P. |last5=Charles |first5=Richelle C. |last6=Jean-Charles |first6=Roger R. |last7=Bullard |first7=James |last8=Webster |first8=Dale R. |last9=Kasarskis |first9=Andrew |last10=Peluso |first10=Paul |last11=Paxinos |first11=Ellen E. |last12=Yamaichi |first12=Yoshiharu |last13=Calderwood |first13=Stephen B. |last14=Mekalanos |first14=John J. |last15=Schadt |first15=Eric E. |last16=Waldor |first16=Matthew K. }}


=== Sleep ===
=== Complex Disease ===


* Scarpa JR, Jiang P, Losic B, Readhead B, Gao VD, Dudley JT, Vitaterna MH, Turek FW, Kasarskis A. Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's Disease. ''PLoS Genet''. 2016 Jul 8;12(7):e1006137. doi: 10.1371/journal.pgen.1006137. PubMed PMID: 27390852; PubMed Central PMCID: PMC4938493. <ref>{{Cite journal|last=Scarpa|first=Joseph R.|last2=Jiang|first2=Peng|last3=Losic|first3=Bojan|last4=Readhead|first4=Ben|last5=Gao|first5=Vance D.|last6=Dudley|first6=Joel T.|last7=Vitaterna|first7=Martha H.|last8=Turek|first8=Fred W.|last9=Kasarskis|first9=Andrew|date=07 2016|title=Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's Disease|url=https://www.ncbi.nlm.nih.gov/pubmed/27390852|journal=PLoS genetics|volume=12|issue=7|pages=e1006137|doi=10.1371/journal.pgen.1006137|issn=1553-7404|pmc=4938493|pmid=27390852}}</ref>
* {{cite journal|title=Pharmacological validation of candidate causal sleep genes identified in an N2 cross |journal=Journal of Neurogenetics |pmc=3568991 | pmid=22091728 |doi=10.3109/01677063.2011.628426 |volume=25 |issue=4 |year=2011 |pages=167–81 | last1 = Brunner | first1 = JI | last2 = Gotter | first2 = AL | last3 = Millstein | first3 = J | last4 = Garson | first4 = S | last5 = Binns | first5 = J | last6 = Fox | first6 = SV | last7 = Savitz | first7 = AT | last8 = Yang | first8 = HS | last9 = Fitzpatrick | first9 = K | last10 = Zhou | first10 = L | last11 = Owens | first11 = JR | last12 = Webber | first12 = AL | last13 = Vitaterna | first13 = MH | last14 = Kasarskis | first14 = A | last15 = Uebele | first15 = VN | last16 = Turek | first16 = F | last17 = Renger | first17 = JJ | last18 = Winrow | first18 = CJ}}
*Michlmayr D, Pak TR, Rahman AH, Amir ED, Kim EY, Kim-Schulze S, Suprun M, Stewart MG, Thomas GP, Balmaseda A, Wang L, Zhu J, Suaréz-Fariñas M, Wolinsky SM, Kasarskis A, Harris E. Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases. ''Mol Syst Biol''. 2018 Aug 27;14(8):e7862. doi: 10.15252/msb.20177862. PubMed PMID: 30150281; PubMed Central PMCID: PMC6110311. <ref>{{Cite journal|last=Michlmayr|first=Daniela|last2=Pak|first2=Theodore R.|last3=Rahman|first3=Adeeb H.|last4=Amir|first4=El-Ad David|last5=Kim|first5=Eun-Young|last6=Kim-Schulze|first6=Seunghee|last7=Suprun|first7=Maria|last8=Stewart|first8=Michael G.|last9=Thomas|first9=Guajira P.|date=08 27, 2018|title=Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases|url=https://www.ncbi.nlm.nih.gov/pubmed/30150281|journal=Molecular Systems Biology|volume=14|issue=8|pages=e7862|doi=10.15252/msb.20177862|issn=1744-4292|pmc=6110311|pmid=30150281}}</ref>
* {{cite journal|url=http://www.journalsleep.org/ViewAbstract.aspx?pid=28326 |title=Identification of causal genes, networks, and transcriptional regulators of REM sleep and wake |journal=Sleep |date= |accessdate=2013-06-17}}
* {{cite journal|title=Uncovering the Genetic Landscape for Multiple Sleep-Wake Traits |journal=PLOS ONE |doi=10.1371/journal.pone.0005161 |volume=4 |issue = 4|pages=e5161 |pmid=19360106 |pmc=2664962 | last1 = Winrow | first1 = CJ | last2 = Williams | first2 = DL | last3 = Kasarskis | first3 = A | last4 = Millstein | first4 = J | last5 = Laposky | first5 = AD | last6 = Yang | first6 = HS | last7 = Mrazek | first7 = K | last8 = Zhou | first8 = L | last9 = Owens | first9 = JR | last10 = Radzicki | first10 = D | last11 = Preuss | first11 = F | last12 = Schadt | first12 = EE | last13 = Shimomura | first13 = K | last14 = Vitaterna | first14 = MH | last15 = Zhang | first15 = C | last16 = Koblan | first16 = KS | last17 = Renger | first17 = JJ | last18 = Turek | first18 = FW|year = 2009|bibcode = 2009PLoSO...4.5161W}}
*{{cite journal|title=Pharmacological validation of candidate causal sleep genes identified in an N2 cross |journal=Journal of Neurogenetics |pmc=3568991 | pmid=22091728 |doi=10.3109/01677063.2011.628426 |volume=25 |issue=4 |year=2011 |pages=167–81 | last1 = Brunner | first1 = JI | last2 = Gotter | first2 = AL | last3 = Millstein | first3 = J | last4 = Garson | first4 = S | last5 = Binns | first5 = J | last6 = Fox | first6 = SV | last7 = Savitz | first7 = AT | last8 = Yang | first8 = HS | last9 = Fitzpatrick | first9 = K | last10 = Zhou | first10 = L | last11 = Owens | first11 = JR | last12 = Webber | first12 = AL | last13 = Vitaterna | first13 = MH | last14 = Kasarskis | first14 = A | last15 = Uebele | first15 = VN | last16 = Turek | first16 = F | last17 = Renger | first17 = JJ | last18 = Winrow | first18 = CJ}}


== References ==
== References ==

Revision as of 20:46, 16 July 2019

Andrew Kasarskis
Born (1972-11-02) November 2, 1972 (age 51)
Madison, Wisconsin
CitizenshipAmerican
Alma materUniversity of Kentucky
University of California, Berkeley
Scientific career
Fieldsbioinformatics, genomics
InstitutionsIcahn School of Medicine at Mount Sinai
Icahn Institute for Genomics and Multiscale

Andrew Kasarskis (born November 2, 1972) is an American biologist. He is the CDO and EVP Mount Sinai Health System in New York City. He was previously vice chair of the Department of Genetics and Genomic Sciences and co-director of the Icahn Institute for Data Science and Genomic Technology at the Icahn School of Medicine at Mount Sinai.[1] Kasarskis is known for taking a network-based approach to biology and for directing the first medical school class offering students the opportunity to fully sequence and analyze their own genomes.[2]

Early Life and Education

Kasarskis completed bachelor's degrees in chemistry and biology at the University of Kentucky in 1992. In 1998, he completed his PhD in molecular and cell biology at the University of California, Berkeley, under the supervision of Kathryn Anderson.[1]

Career and Research

Throughout his career in industry and academia, Kasarskis’s research has focused on the use of genetic and genomic data together with high-performance computing and advanced analytical tools to address biomedical needs and improve clinical treatment.

After completing his PhD, Kasarskis worked at Stanford University for two years, contributing to the development of various genome databases. In 2000, he entered industry, working in computational biology at DoubleTwist and later Rosetta Inpharmatics (acquired by Merck Research Laboratories). His work there centered on generating and mining complex biological data sets and using that information to build, predict, and model human disease. Kasarskis also worked for Sage Bionetworks and Pacific Biosciences before returning to academia.[3]

In 2011, Kasarskis became vice chair of the department of genetics and genomic sciences at the Icahn School of Medicine at Mount Sinai and co-director, along with Eric Schadt, of the Icahn Institute for Genomics and Multiscale Biology, where the goal is to use large-scale data analysis to improve patient treatment.[4][5] His focus is on improving health outcomes through better data mining, and his research program includes sequencing-based pathogen surveillance; pharmacogenomics; electronic health records; and systems biology of sleep, behavior, and stress.[1]

Kasarskis is known for directing the first class that allowed medical and PhD students to fully sequence and analyze their own genomes, along with co-instructors Michael Linderman, George Diaz, Ali Bashir, and Randi Zinberg. He has said that courses like this will be critical for training teams of people capable of performing this type of analysis in a medical setting. He chose whole genome sequencing because he expects the more limited exome sequencing will not be a relevant technological approach in the long term.[2]

Kasarskis has called for improvements to informed consent protocols in patient research based on the concept that studies involving DNA cannot fully be made anonymous. He was quoted in the journal Nature saying, “We need to move beyond an assumption that you cannot be identified from the data that exist about you and really work to make sure that we’re protecting people’s rights in ways that allow us to use the data that are out there for individuals’ and researchers’ benefit.”[6]

Kasarskis's latest research focuses on asthma and clinical data infrastructures. In his new role as Chief Data Officer of Mount Sinai Health System and Executive Vice President Andrew is evaluating Mount Sinai's biomedical data and how the data can be used to advance patient outcomes.

Selected publications

Pharmacogenomics

  • Smith, Catherine C.; Wang, Qi; Chin, Chen-Shan; Salerno, Sara; Damon, Lauren E.; Levis, Mark J.; Perl, Alexander E.; Travers, Kevin J.; Wang, Susana; Hunt, Jeremy P.; Zarrinkar, Patrick P.; Schadt, Eric E.; Kasarskis, Andrew; Kuriyan, John; Shah, Neil P. (2012). "Validation of ITD mutations in FLT3 as a therapeutic target in human acute myeloid leukaemia". Nature. 485 (7397): 260–263. Bibcode:2012Natur.485..260S. doi:10.1038/nature11016. PMC 3390926. PMID 22504184.
  • Kasarskis, Andrew; Yang, Xia; Schadt, Eric (2011). "Integrative genomics strategies to elucidate the complexity of drug response". Pharmacogenomics. 12 (12): 1695–1715. doi:10.2217/pgs.11.115. PMID 22118053.
  • Gargis, Amy S.; Kalman, Lisa; Berry, Meredith W.; Bick, David P.; Dimmock, David P.; Hambuch, Tina; Lu, Fei; Lyon, Elaine; Voelkerding, Karl V.; Zehnbauer, Barbara A.; Agarwala, Richa; Bennett, Sarah F.; Chen, Bin; Chin, Ephrem L H.; Compton, John G.; Das, Soma; Farkas, Daniel H.; Ferber, Matthew J.; Funke, Birgit H.; Furtado, Manohar R.; Ganova-Raeva, Lilia M.; Geigenmüller, Ute; Gunselman, Sandra J.; Hegde, Madhuri R.; Johnson, Philip L F.; Kasarskis, Andrew; Kulkarni, Shashikant; Lenk, Thomas; Liu, C S Jonathan; Manion, Megan (2012). "Assuring the quality of next-generation sequencing in clinical laboratory practice". Nature Biotechnology. 30 (11): 1033–1036. doi:10.1038/nbt.2403. PMC 3827024. PMID 23138292. {{cite journal}}: Unknown parameter |displayauthors= ignored (|display-authors= suggested) (help)

Pathogens

  • Genomic Surveillance Reveals Diversity of Multidrug-Resistant Organism Colonization and Infection: A Prospective Cohort Study in Liver Transplant Recipients Nenad Macesic, Angela Gomez-Simmonds, Sean B Sullivan, Marla J Giddins, Samantha A Ferguson, Gautam Korakavi, David Leeds, Sarah Park, Kevin Shim, Madeleine G Sowash, Melanie Hofbauer, Ryan Finkel, Yue Hu, Jared West, Nora C Toussaint, William G Greendyke, Benjamin A Miko, Marcus R Pereira, Susan Whittier, Elizabeth C Verna, Anne-Catrin Uhlemann Clin Infect Dis. 2018 Sep 15; 67(6): 905–912. Published online 2018 Apr 28. doi: 10.1093/cid/ciy199[7]
  • Pak TR, Chacko KI, O'Donnell T, Huprikar SS, van Bakel H, Kasarskis A, Scott ER. Estimating Local Costs Associated With Clostridium difficile Infection Using Machine Learning and Electronic Medical Records. Infect Control Hosp Epidemiol. 2017 Dec;38(12):1478-1486. doi: 10.1017/ice.2017.214. Epub 2017 Nov 6. PubMed PMID: 29103378; PubMed Central PMCID: PMC5923033.[8]
  • Rasko, David A.; Webster, Dale R.; Sahl, Jason W.; Bashir, Ali; Boisen, Nadia; Scheutz, Flemming; Paxinos, Ellen E.; Sebra, Robert; Chin, Chen-Shan; Iliopoulos, Dimitris; Klammer, Aaron; Peluso, Paul; Lee, Lawrence; Kislyuk, Andrey O.; Bullard, James; Kasarskis, Andrew; Wang, Susanna; Eid, John; Rank, David; Redman, Julia C.; Steyert, Susan R.; Frimodt-Møller, Jakob; Struve, Carsten; Petersen, Andreas M.; Krogfelt, Karen A.; Nataro, James P.; Schadt, Eric E.; Waldor, Matthew K. (2011). "Origins of the E. coli Strain Causing an Outbreak of Hemolytic–Uremic Syndrome in Germany". New England Journal of Medicine. 365 (8): 709–717. doi:10.1056/NEJMoa1106920. PMC 3168948. PMID 21793740.
  • Chin, Chen-Shan; Sorenson, Jon; Harris, Jason B.; Robins, William P.; Charles, Richelle C.; Jean-Charles, Roger R.; Bullard, James; Webster, Dale R.; Kasarskis, Andrew; Peluso, Paul; Paxinos, Ellen E.; Yamaichi, Yoshiharu; Calderwood, Stephen B.; Mekalanos, John J.; Schadt, Eric E.; Waldor, Matthew K. (2011). "The origin of the Haitian cholera outbreak strain". New England Journal of Medicine. 364 (1): 33–42. doi:10.1056/NEJMoa1012928. PMC 3030187. PMID 21142692.

Complex Disease

  • Scarpa JR, Jiang P, Losic B, Readhead B, Gao VD, Dudley JT, Vitaterna MH, Turek FW, Kasarskis A. Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's Disease. PLoS Genet. 2016 Jul 8;12(7):e1006137. doi: 10.1371/journal.pgen.1006137. PubMed PMID: 27390852; PubMed Central PMCID: PMC4938493. [9]
  • Michlmayr D, Pak TR, Rahman AH, Amir ED, Kim EY, Kim-Schulze S, Suprun M, Stewart MG, Thomas GP, Balmaseda A, Wang L, Zhu J, Suaréz-Fariñas M, Wolinsky SM, Kasarskis A, Harris E. Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases. Mol Syst Biol. 2018 Aug 27;14(8):e7862. doi: 10.15252/msb.20177862. PubMed PMID: 30150281; PubMed Central PMCID: PMC6110311. [10]
  • Brunner, JI; Gotter, AL; Millstein, J; Garson, S; Binns, J; Fox, SV; Savitz, AT; Yang, HS; Fitzpatrick, K; Zhou, L; Owens, JR; Webber, AL; Vitaterna, MH; Kasarskis, A; Uebele, VN; Turek, F; Renger, JJ; Winrow, CJ (2011). "Pharmacological validation of candidate causal sleep genes identified in an N2 cross". Journal of Neurogenetics. 25 (4): 167–81. doi:10.3109/01677063.2011.628426. PMC 3568991. PMID 22091728.

References

  1. ^ a b c "Andrew Kasarskis - Icahn School of Medicine at Mount Sinai". Icahn.mssm.edu. Retrieved 2013-06-10.
  2. ^ a b Nicholas Tatonetti. "Q&A: Mount Sinai's Andrew Kasarskis on Teaching Students how to Analyze their Own Genomes | Clinical Sequencing News | Sequencing". GenomeWeb. Retrieved 2013-06-10.
  3. ^ "BIOMEDIN 206: Informatics in Industry - Stanford University". Stanford.edu. Retrieved 2013-06-10.
  4. ^ Samuelson, Tracey (2012-07-12). "Looking at the Big Picture: How Big Data Gets Personal". WNYC. Retrieved 2013-06-10.
  5. ^ Nicholas Tatonetti. "Mount Sinai, RPI to Collaborate on Bioinformatics Apps as Part of Academic Research Pact | BioInform | Informatics". GenomeWeb. Retrieved 2013-06-10.
  6. ^ Check Hayden, Erika (2012-04-25). "Open-data project aims to ease the way for genomic research". Nature News. Nature.com. doi:10.1038/nature.2012.10507. Retrieved 2013-06-10.
  7. ^ Pak, Theodore R.; Kasarskis, Andrew (2015-12-01). "How next-generation sequencing and multiscale data analysis will transform infectious disease management". Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America. 61 (11): 1695–1702. doi:10.1093/cid/civ670. ISSN 1537-6591. PMC 4643486. PMID 26251049.
  8. ^ Pak, Theodore R.; Chacko, Kieran I.; O'Donnell, Timothy; Huprikar, Shirish S.; van Bakel, Harm; Kasarskis, Andrew; Scott, Erick R. (12 2017). "Estimating Local Costs Associated With Clostridium difficile Infection Using Machine Learning and Electronic Medical Records". Infection Control and Hospital Epidemiology. 38 (12): 1478–1486. doi:10.1017/ice.2017.214. ISSN 1559-6834. PMC 5923033. PMID 29103378. {{cite journal}}: Check date values in: |date= (help)
  9. ^ Scarpa, Joseph R.; Jiang, Peng; Losic, Bojan; Readhead, Ben; Gao, Vance D.; Dudley, Joel T.; Vitaterna, Martha H.; Turek, Fred W.; Kasarskis, Andrew (07 2016). "Systems Genetic Analyses Highlight a TGFβ-FOXO3 Dependent Striatal Astrocyte Network Conserved across Species and Associated with Stress, Sleep, and Huntington's Disease". PLoS genetics. 12 (7): e1006137. doi:10.1371/journal.pgen.1006137. ISSN 1553-7404. PMC 4938493. PMID 27390852. {{cite journal}}: Check date values in: |date= (help)CS1 maint: unflagged free DOI (link)
  10. ^ Michlmayr, Daniela; Pak, Theodore R.; Rahman, Adeeb H.; Amir, El-Ad David; Kim, Eun-Young; Kim-Schulze, Seunghee; Suprun, Maria; Stewart, Michael G.; Thomas, Guajira P. (08 27, 2018). "Comprehensive innate immune profiling of chikungunya virus infection in pediatric cases". Molecular Systems Biology. 14 (8): e7862. doi:10.15252/msb.20177862. ISSN 1744-4292. PMC 6110311. PMID 30150281. {{cite journal}}: Check date values in: |date= (help)
Retrieved from "https://en.wikipedia.org/w/index.php?title=Andrew_Kasarskis&oldid=906587575"