MARCH2: Difference between revisions

From Wikipedia, the free encyclopedia
Browse history interactively
← Previous editNext edit →
Content deleted Content added
VisualWikitext
OAbot (talk | contribs)
Bots
418,853 edits
m Open access bot: doi added to citation with #oabot.
Oshah (talk | contribs)
431 edits
Note for using in Excel
Line 1: Line 1:
{{Infobox_gene}}
{{Infobox_gene}}
'''E3 ubiquitin-protein ligase MARCH2''' is an [[enzyme]] that in humans is encoded by the ''MARCH2'' [[gene]].<ref name="pmid11042152">{{cite journal | vauthors = Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z | title = Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells | journal = Genome Research | volume = 10 | issue = 10 | pages = 1546–60 | date = October 2000 | pmid = 11042152 | pmc = 310934 | doi = 10.1101/gr.140200 }}</ref><ref name="pmid14722266">{{cite journal | vauthors = Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Früh K | title = Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins | journal = Journal of Virology | volume = 78 | issue = 3 | pages = 1109–20 | date = February 2004 | pmid = 14722266 | pmc = 321412 | doi = 10.1128/JVI.78.3.1109-1120.2004 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MARCH2 membrane-associated ring finger (C3HC4) 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51257| access-date = }}</ref> It is a member of the MARCH family of E3 ligases, and plays an important role in the [[Protein turnover|turnover]] of [[membrane proteins]].<ref name="Zhang_2018">{{cite journal | vauthors = Zhang Y, Lu J, Liu X | title = MARCH2 is upregulated in HIV-1 infection and inhibits HIV-1 production through envelope protein translocation or degradation | journal = Virology | volume = 518 | issue = | pages = 293–300 | date = May 2018 | pmid = 29573664 | doi = 10.1016/j.virol.2018.02.003 | doi-access = free }}</ref>
'''E3 ubiquitin-protein ligase MARCH2''' is an [[enzyme]] that in humans is encoded by the ''MARCH2'' [[gene]].<ref name="pmid11042152">{{cite journal | vauthors = Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z | title = Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells | journal = Genome Research | volume = 10 | issue = 10 | pages = 1546–60 | date = October 2000 | pmid = 11042152 | pmc = 310934 | doi = 10.1101/gr.140200 }}</ref><ref name="pmid14722266">{{cite journal | vauthors = Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Früh K | title = Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins | journal = Journal of Virology | volume = 78 | issue = 3 | pages = 1109–20 | date = February 2004 | pmid = 14722266 | pmc = 321412 | doi = 10.1128/JVI.78.3.1109-1120.2004 }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: MARCH2 membrane-associated ring finger (C3HC4) 2| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=51257| access-date = }}</ref> It is a member of the MARCH family of E3 ligases, and plays an important role in the [[Protein turnover|turnover]] of [[membrane proteins]].<ref name="Zhang_2018">{{cite journal | vauthors = Zhang Y, Lu J, Liu X | title = MARCH2 is upregulated in HIV-1 infection and inhibits HIV-1 production through envelope protein translocation or degradation | journal = Virology | volume = 518 | issue = | pages = 293–300 | date = May 2018 | pmid = 29573664 | doi = 10.1016/j.virol.2018.02.003 | doi-access = free }}</ref>

== Gene name error in Excel ==

{{Main|Microsoft Excel#Conversion_problems}}

Like the other MARCH and [[septin]] genes, care must be exercised when analyzing genetic data containing the MARCH2 gene in [[Microsoft Excel]].<ref name=ExcelAteMyDNA>{{cite journal|last1=Zeeberg|first1=Barry R|last2=Riss|first2=Joseph|last3=Kane|first3=David W|last4=Bussey|first4=Kimberly J|last5=Uchio|first5=Edward|last6=Linehan|first6=W Marston|last7=Barrett|first7=J Carl|last8=Weinstein|first8=John N|journal=[[BMC Bioinformatics]]|volume=5|issue=1|year=2004|pages=80|pmid=15214961|pmc=459209|doi=10.1186/1471-2105-5-80|doi-access=free|title=Mistaken Identifiers: Gene name errors can be introduced inadvertently when using Excel in bioinformatics}}</ref> This is due to Excel's autocorrect feature treating the MARCH gene as a date and converting it to a standard date format. The original text cannot be recovered as a result of the conversion. A 2016 study found up to 19.6% of all papers in selected journals to be affected by the gene name error.<ref>{{Cite journal|last=Ziemann|first=Mark|last2=Eren|first2=Yotam|last3=El-Osta|first3=Assam|date=2016-08-23|title=Gene name errors are widespread in the scientific literature|url=https://doi.org/10.1186/s13059-016-1044-7|journal=Genome Biology|volume=17|issue=1|pages=177|doi=10.1186/s13059-016-1044-7|issn=1474-760X|pmc=PMC4994289|pmid=27552985}}</ref> The issue can be prevented by using an alias name such as MARCHF2, prepending with an apostrophe ('), or preformatting the cell as text.



== References ==
== References ==

Revision as of 00:49, 7 August 2020

MARCHF2
Identifiers
AliasesMARCHF2, MARCH-II, RNF172, HSPC240, membrane associated ring-CH-type finger 2, MARCH2
External IDsOMIM: 613332 MGI: 1925915 HomoloGene: 9539 GeneCards: MARCHF2
Orthologs
SpeciesHumanMouse
Entrez

51257

224703

Ensembl

ENSG00000099785

ENSMUSG00000079557

UniProt

Q9P0N8

Q99M02

RefSeq (mRNA)

NM_001252480
NM_145486

RefSeq (protein)

NP_001239409
NP_663461

Location (UCSC)Chr 19: 8.41 – 8.44 MbChr 17: 33.9 – 33.94 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

E3 ubiquitin-protein ligase MARCH2 is an enzyme that in humans is encoded by the MARCH2 gene.[5][6][7] It is a member of the MARCH family of E3 ligases, and plays an important role in the turnover of membrane proteins.[8]

Gene name error in Excel

Main article: Microsoft Excel § Conversion_problems

Like the other MARCH and septin genes, care must be exercised when analyzing genetic data containing the MARCH2 gene in Microsoft Excel.[9] This is due to Excel's autocorrect feature treating the MARCH gene as a date and converting it to a standard date format. The original text cannot be recovered as a result of the conversion. A 2016 study found up to 19.6% of all papers in selected journals to be affected by the gene name error.[10] The issue can be prevented by using an alias name such as MARCHF2, prepending with an apostrophe ('), or preformatting the cell as text.


References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000099785 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000079557 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zhang QH, Ye M, Wu XY, Ren SX, Zhao M, Zhao CJ, Fu G, Shen Y, Fan HY, Lu G, Zhong M, Xu XR, Han ZG, Zhang JW, Tao J, Huang QH, Zhou J, Hu GX, Gu J, Chen SJ, Chen Z (October 2000). "Cloning and functional analysis of cDNAs with open reading frames for 300 previously undefined genes expressed in CD34+ hematopoietic stem/progenitor cells". Genome Research. 10 (10): 1546–60. doi:10.1101/gr.140200. PMC 310934. PMID 11042152.
  6. ^ Bartee E, Mansouri M, Hovey Nerenberg BT, Gouveia K, Früh K (February 2004). "Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins". Journal of Virology. 78 (3): 1109–20. doi:10.1128/JVI.78.3.1109-1120.2004. PMC 321412. PMID 14722266.
  7. ^ "Entrez Gene: MARCH2 membrane-associated ring finger (C3HC4) 2".
  8. ^ Zhang Y, Lu J, Liu X (May 2018). "MARCH2 is upregulated in HIV-1 infection and inhibits HIV-1 production through envelope protein translocation or degradation". Virology. 518: 293–300. doi:10.1016/j.virol.2018.02.003. PMID 29573664.
  9. ^ Zeeberg, Barry R; Riss, Joseph; Kane, David W; Bussey, Kimberly J; Uchio, Edward; Linehan, W Marston; Barrett, J Carl; Weinstein, John N (2004). "Mistaken Identifiers: Gene name errors can be introduced inadvertently when using Excel in bioinformatics". BMC Bioinformatics. 5 (1): 80. doi:10.1186/1471-2105-5-80. PMC 459209. PMID 15214961.
  10. ^ Ziemann, Mark; Eren, Yotam; El-Osta, Assam (2016-08-23). "Gene name errors are widespread in the scientific literature". Genome Biology. 17 (1): 177. doi:10.1186/s13059-016-1044-7. ISSN 1474-760X. PMC 4994289. PMID 27552985.{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: unflagged free DOI (link)

Further reading


Stub icon

This article on a gene on human chromosome 19 is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=MARCH2&oldid=971579901"