There had been multiple Senators teams in higher-classification leagues such as the New York State League, the Eastern League that played between 1916 and 1932, the International League, the 1923–1937 New York-Pennsylvania League, and the modern Eastern League, in which it played 22 consecutive seasons, 1938–1959, before the team disbanded. An early Senators team also played in "outlaw" minor leagues such as the Hudson River League during the 19th century in between stints in "organized baseball."
The Senators won six league championships over their organized baseball history, the last in 1954. The club was a powerhouse during the 1940s as a Class A farm team of the Pittsburgh Pirates, posting winning records between 1942–1948, making the Eastern League playoffs six times, leading in attendance five times, and taking the 1945 EL championship. Among the Pittsburgh farmhands who played for the club was Hall of Famer Ralph Kiner, in 1941–1942.
Over the years, different Senators teams were affiliated with MLB clubs such as the New York Yankees, Washington Senators, Cincinnati Reds, Boston Red Sox and Kansas City Athletics. The last-place 1959 Senators — the latest in a succession of poor clubs — drew only 45,000 fans for the season and Albany was dropped from the Eastern League when it contracted from eight to six teams for 1960. Professional baseball and the EL would not return to New York's state capital until 1983, when the West Haven A's moved to the area as the Albany-Colonie A's (now Richmond Flying Squirrels). The current pro baseball team in the Albany area is the Tri-City ValleyCats of the New York–Penn League.
Today, there is only one Senators franchise that still exists which the International League incarnation. The International League incarnation is today now known as the Moosic, Pennsylvania based Scranton/Wilkes-Barre Yankees.
- Johnson, Lloyd, and Wolff, Miles, eds., The Encyclopedia of Minor League Baseball, 3rd edition. Durham, N.C.: Baseball America, 2007.