American Association of Poison Control Centers
The American Association of Poison Control Centers (AAPCC) is a national voluntary health organization founded in 1958 that represents the nation’s 57 poison centers. The AAPCC supports poison centers in their public health mission to prevent poisonings, provide education, conduct scientific research and treat individuals exposed to poisoning from medications, environmental events, plants, animals, and household products or toxins. The AAPCC also supports the efforts of poison centers and interested individuals to reduce morbidity and mortality from unintentional poisonings. The AAPCC sets standards for poison center operations and certifies specialists in poison information who are available 24/7 to respond to public, health-care provider and emergency medical service personnel requests for assistance. In addition, the AAPCC maintains the National Poison Data System, the only poison information and surveillance database in the United States.
Key AAPCC Activities
- Accreditation of regional poison centers and certification of poison center personnel
- Publication of the annual report of the American Association of Poison Control Centers’ National Poison Data System (NPDS) published every December in Clinical Toxicology
- Interaction with private and governmental agencies whose activities influence poisoning and poison centers
- Co-hosting a national conference of poison center leaders that includes scientific presentations, business meetings, and committee meetings
- Development of public and professional education programs and materials
- Collection and analysis of national poisoning data
- Promotion and support of legislation to improve poison prevention practices and programs
- Participation on and partnerships with national coalitions and committees to advance public safety and poison prevention 
United States poison centers compose a remarkable nationwide medical calls system. A single toll-free telephone number immediately connects a caller to a specialist in poison information anywhere in the U.S. at any time, day or night. A board-certified toxicologist can be reached within a few moments to provide confidential, expert medical advice to people who have been exposed to a poison. This extraordinary system is maintained by the voluntary cooperation of the 57 member organizations of the AAPCC.
The 24-hour national toll-free Poison Help line provides immediate poison information and emergency instructions to all callers regardless of health insurance, immigration status, or language preference from any U.S. telephone or cell phone. Calls are answered by physicians, nurses and pharmacists with highly specialized training in poison management. Poison center services are accessible to all populations, including under-served and undocumented groups, those speaking one of 150 languages and those utilizing telecommunication devices for the hearing impaired (TDD/TTY). More than 70 percent of all cases received by poison centers can be safely and effectively treated at home, without need for further medical care.
Cost Savings for the Health-Care System
Substantial cost savings have been attributed to poison center reductions in unnecessary emergency department (ED) care through accurate assessment and triage of poisoning exposures. The public health and cost benefits from poison center pre-hospital management of patients not needing ED visits favorably impacts the self-pay or copaying general public, the health-care institution supporting the costs of indigent care, the commercial insurance companies and governmental health-care funding agencies. Poison centers assess and manage more than 70 percent of poison exposures over the phone, eliminating the need for callers to seek further medical care. This reduction in medically unnecessary ED visits decreases hospital overcrowding and minimizes unnecessary ambulance runs, freeing critical emergency staff to handle true emergencies more effectively.
National Poison Data System (NPDS)
The AAPCC owns and manages a large database of information from all poison exposure and information case phone calls to all poison centers across the country. It is the only near real-time, comprehensive poisoning surveillance database in the United States.
NPDS holds more than 50 million poison exposure case records, with more than 2 million new records added each year. It is also a robust and modern system – holding technical medical information that is searchable in many ways. NPDS contains exposure cases dating back to 1985. Today, information and exposure case data is continually uploaded to NPDS from all the poison centers in near “real time.”
- guide clinical research on poisonings.
- prompt new product and medicine formulas.
- help provide evidence for product repackaging, recalls, bans, over-the-counter status changes, product reformulation.
- focus poison prevention education.
- direct training of future medical students.
- detect chemical or bioterrorism incidents.
Key regulatory agencies that rely on NPDS data: 
- Centers for Disease Control and Prevention (CDC)
- Food and Drug Administration (FDA)
- Environmental Protection Agency (EPA)
- Drug Enforcement Administration (DEA)
- Consumer Product Safety Commission (CPSC)
NPDS data is also frequently used by pharmaceutical manufacturers.
- Clinical Toxicology, the official journal of the AAPCC.
- Carr, Debbie; Richard C. Dart (2012). "American Association of Poison Control Centers". Encyclopedia of Toxicology. 3rd Edition: 487.
- Dart, MD, PhD, Richard C. (January 2012). "The Secret Life of America's Poison Centers". Annals of Emergency Medicine 59 (1): 62–66.
- King, WD.; PA. Palmisano (June 1991). "Poison Control Centers: Can Their Value be Measured?". Southern Medical Journal 84 (6): 722–726.
- Miller, T.R.; et al. (February 1997). "Costs of Poisoning in the United States and Savings from Poison Control Centers: A Cost-Benefit Analysis". Annals of Emergency Medicine 29 (2): 239–245.