Founded on 5 April 1953, Domingo Borja became their first president. He was succeeded by Guillermo Vargas Roldán who oversaw the club's rise to ultimately the top tier of Costa Rican football. They remained there for 20 years until their relegation in 1988, clinched promotion again in 1992 and were in the Segunda División de Costa Rica again from 1999 to 2003 and from 2006 to 2008. They had two players at Costa Rica's first World Cup appearance: Luis Gabelo Conejo and Mauricio Montero.
Ramonense won promotion to the Primera División de Costa Rica for the 2008-09 season by winning a play-off against Municipal Grecia. Ramonense had previously won promotion to the Primera in 1967, 1992 and 2003. Ramonense classify to the second round in the temp 2008-2009.
In 2010, the club was renamed from Asociación Deportiva Ramonense to Club Deportivo Ramonense Poeta de Occidente. In 2012, the club return to its traditional name.