Covalent modulation

Covalent modulation is the alteration of a protein's shape and function by covalent bonding of chemical groups to it.

Covalent modulation is the alteration of a protein's shape and function by covalent bonding of chemical groups to it. Enzymes that control metabolic pathways can be subject to reversible regulation by phosphorylation of specific sites. This reversible phosphorylation affects the activity of the enzyme.

Types

• Phosphorylation
• Glycosylation
• Methylation