GGTL3

From Wikipedia, the free encyclopedia
Jump to: navigation, search
Gamma-glutamyltransferase 7
Identifiers
Symbols GGT7 ; D20S101; GGT4; GGTL3; GGTL5; dJ18C9.2
External IDs OMIM612342 MGI1913385 HomoloGene70866 GeneCards: GGT7 Gene
EC number 2.3.2.2, 3.4.19.13
Orthologs
Species Human Mouse
Entrez 2686 207182
Ensembl ENSG00000131067 ENSMUSG00000027603
UniProt Q9UJ14 Q99JP7
RefSeq (mRNA) NM_178026 NM_144786
RefSeq (protein) NP_821158 NP_659035
Location (UCSC) Chr 20:
33.43 – 33.46 Mb
Chr 2:
155.49 – 155.52 Mb
PubMed search [1] [2]

Gamma-glutamyltransferase 7 is an enzyme that in humans is encoded by the GGT7 gene.[1][2][3]

Gamma-glutamyltransferase is a membrane-associated protein involved in both the metabolism of glutathione and in the transpeptidation of amino acids. Changes in the activity of gamma-glutamyltransferase may signal preneoplastic or toxic conditions in the liver or kidney. The protein encoded by this gene is similar in sequence to gamma-glutamyltransferase, but its function is unknown.[3]

References[edit]

  1. ^ Figlewicz DA, Delattre O, Guellaen G, Krizus A, Thomas G, Zucman J, Rouleau GA (Oct 1993). "Mapping of human gamma-glutamyl transpeptidase genes on chromosome 22 and other human autosomes". Genomics 17 (2): 299–305. doi:10.1006/geno.1993.1325. PMID 8104871. 
  2. ^ Heisterkamp N, Groffen J, Warburton D, Sneddon TP (Apr 2008). "The human gamma-glutamyltransferase gene family". Hum Genet 123 (4): 321–32. doi:10.1007/s00439-008-0487-7. PMID 18357469. 
  3. ^ a b "Entrez Gene: GGTL3 gamma-glutamyltransferase-like 3". 

Further reading[edit]