Kathrin Muegge
 | This article relies largely or entirely on a single source. (May 2020) |
Kathrin Muegge | |
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| Alma mater | Hannover Medical School (MD) |
| Scientific career | |
| Fields | Molecular biology, epigenetics, cancer research |
| Institutions | Frederick National Laboratory for Cancer Research |
Kathrin Muegge is a German physician and molecular biologist researching chromatin organization during embryonic development and in tumor progression. She is a senior investigator and head of the epigenetics section at the Frederick National Laboratory for Cancer Research.
Education
Kathrin Muegge obtained a M.D. degree at the Hannover Medical School. As a postdoctoral researcher, she worked on cytokines and T cell development in the National Cancer Institute (NCI) Laboratory of Molecular Immunoregulation of Joost J. Oppenheim and Scott K. Durum.[1]
Career and research
As a principal investigator at the Frederick National Laboratory for Cancer Research she investigates in the Laboratory of Cancer Prevention chromatin organization during embryonic development and in tumor progression.[1] She is a senior investigator in the mouse cancer genetics program and head of the epigenetics section.
Muegge studies molecular mechanisms that alter chromatin structure and function during murine development. She discovered several links between chromatin modifiers, including nucleosomal remodeling and DNA methylation. The work focuses on chromatin changes during normal cellular differentiation and during the reverse process of nuclear reprogramming. Her studies provide insights how stable gene expression is achieved, how cells maintain a proper phenotype, and how this process may be disturbed in pathologic conditions including cancer.[1]
References
- ^ a b c "Kathrin Muegge, M.D." Center for Cancer Research. 2014-08-12. Retrieved 2020-05-09.
This article incorporates text from this source, which is in the public domain.
This article incorporates public domain material from websites or documents of the National Institutes of Health.
- Living people
- National Institutes of Health people
- 21st-century women scientists
- Women medical researchers
- German medical researchers
- Cancer researchers
- 21st-century biologists
- German molecular biologists
- Women molecular biologists
- German women biologists
- German emigrants to the United States
- Expatriate academics in the United States
- 21st-century German physicians
- German women physicians
- 21st-century women physicians
- 21st-century German women