MIB1 (gene)

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Mindbomb E3 ubiquitin protein ligase 1
Symbols MIB1 ; DIP-1; DIP1; LVNC7; MIB; ZZANK2; ZZZ6
External IDs OMIM608677 MGI2443157 HomoloGene10810 GeneCards: MIB1 Gene
RNA expression pattern
PBB GE MIB1 gnf1h02349 at tn.png
PBB GE MIB1 gnf1h08014 at tn.png
PBB GE MIB1 gnf1h08614 s at tn.png
More reference expression data
Species Human Mouse
Entrez 57534 225164
Ensembl ENSG00000101752 ENSMUSG00000024294
UniProt Q86YT6 Q80SY4
RefSeq (mRNA) NM_020774 NM_144860
RefSeq (protein) NP_065825 NP_659109
Location (UCSC) Chr 18:
19.28 – 19.45 Mb
Chr 18:
10.73 – 10.82 Mb
PubMed search [1] [2]

E3 ubiquitin-protein ligase MIB1 is an enzyme that in humans is encoded by the MIB1 gene.[1] It is involved in regulating apoptosis.[2]

Confusion with proliferative marker[edit]

An antibody directed at the protein Ki-67, a product of the MKI67 gene, is called MIB-1.[3] The MIB1 gene, which regulates apoptosis, should not be confused with the MIB-1 antibody, which is used to measure Ki-67 expression.


  1. ^ "Entrez Gene: MIB1 mindbomb homolog 1 (Drosophila)". 
  2. ^ MIB1. OMIM.URL: http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=608677. Accessed on: April 24, 2009.
  3. ^ MIB-1. Veripath OncoDiagnostics. http://www.oncodx.org/onco/mib_1.htm. Accessed on: April 24, 2009.

Further reading[edit]