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Protein-coding gene in the species Homo sapiens
MORC family CW-type zinc finger protein 3 is a protein that in humans is encoded by the MORC3 gene .[ 5] [ 6]
This gene encodes a protein that localizes to the nuclear matrix. The protein also has RNA binding activity, and has a predicted coiled-coil domain.[ 6]
References
Further reading
Nagase T, Seki N, Tanaka A, et al. (1996). "Prediction of the coding sequences of unidentified human genes. IV. The coding sequences of 40 new genes (KIAA0121-KIAA0160) deduced by analysis of cDNA clones from human cell line KG-1" . DNA Res . 2 (4): 167–74, 199–210. doi :10.1093/dnares/2.4.167 . PMID 8590280 .
Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery" . Genome Res . 6 (9): 791–806. doi :10.1101/gr.6.9.791 . PMID 8889548 .
Hattori M, Fujiyama A, Taylor TD, et al. (2000). "The DNA sequence of human chromosome 21" . Nature . 405 (6784): 311–9. Bibcode :2000Natur.405..311H . doi :10.1038/35012518 . PMID 10830953 .
Kimura Y, Sakai F, Nakano O, et al. (2002). "The newly identified human nuclear protein NXP-2 possesses three distinct domains, the nuclear matrix-binding, RNA-binding, and coiled-coil domains" . J. Biol. Chem . 277 (23): 20611–7. doi :10.1074/jbc.M201440200 . PMID 11927593 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 . PMID 14702039 .
Rosendorff A, Sakakibara S, Lu S, et al. (2006). "NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression" . Proc. Natl. Acad. Sci. U.S.A . 103 (14): 5308–13. Bibcode :2006PNAS..103.5308R . doi :10.1073/pnas.0601066103 . PMC 1459351 . PMID 16567619 .
Takahashi K, Yoshida N, Murakami N, et al. (2007). "Dynamic regulation of p53 subnuclear localization and senescence by MORC3" . Mol. Biol. Cell . 18 (5): 1701–9. doi :10.1091/mbc.E06-08-0747 . PMC 1855011 . PMID 17332504 .