The PKCS #11 standard defines a platform-independent API to cryptographic tokens, such as hardware security modules (HSM) and smart cards, and names the API itself "Cryptoki" (from "cryptographic token interface" and pronounced as "crypto-key" - but "PKCS #11" is often used to refer to the API as well as the standard that defines it.
The API defines most commonly used cryptographic object types (RSA keys, X.509 Certificates, DES/Triple DES keys, etc.) and all the functions needed to use, create/generate, modify and delete those objects.
Most commercial certificate authority software uses PKCS #11 to access the CA signing key or to enroll user certificates. Cross-platform software that needs to use smart cards uses PKCS #11, such as Mozilla Firefox and OpenSSL (using an extension). It is also used to access smart cards and HSMs. Software written for Microsoft Windows may use the platform specific MS-CAPI API instead.