Jump to content

PhIP-Seq

Add links
From Wikipedia, the free encyclopedia

This is an old revision of this page, as edited by Citation bot (talk | contribs) at 14:07, 5 December 2019 (Add: pmid, issue. Removed URL that duplicated unique identifier. | You can use this bot yourself. Report bugs here.| Activated by User:Nemo bis | via #UCB_webform). The present address (URL) is a permanent link to this revision, which may differ significantly from the current revision.

Phage immunoprecipitation sequencing (PhIP-Seq) is method that combines barcoded DNA high-throughput sequencing and proteomics to determine the levels of binding of antibodies to epitopes. It has been used to study the autoantibody repertoire of autoimmune diseases like multiple sclerosis, type 2 diabetes and rheumatoid arthritis.[1][2]

References

  1. ^ Larman, H; et al. (2011). "Autoantigen discovery with a synthetic human peptidome". Nature Biotechnology. 29 (6): 535–541. doi:10.1038/nbt.1856. PMC 4169279. PMID 21602805.
  2. ^ Larman, H; et al. (June 2013). "PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis". Journal of Autoimmunity. 43: 1–9. doi:10.1016/j.jaut.2013.01.013. PMC 3677742. PMID 23497938.


Stub icon

This genetics article is a stub. You can help Wikipedia by expanding it.

Retrieved from "https://en.wikipedia.org/w/index.php?title=PhIP-Seq&oldid=929386283"