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SPE may refer to:

Science and technology[edit]

Computer science[edit]

  • Stani's Python Editor, a multi-platform IDE for the Python programming language
  • Synergistic Processing Element, part of the Cell microprocessor used in the PlayStation 3 video game console
  • Software performance engineering, in performance engineering
  • Signal-Processing Engine, for example in the PowerPC e500


Professional societies[edit]


  • Supervisory patent examiner, a patent examiner, usually a civil servant, working at a patent office
  • SPE Certified, a food quality assurance certification