Biakabutuka is perhaps best known for his 313-yard rushing effort against Ohio State in 1995, which helped Michigan upset the previously-undefeated Buckeyes. His performance against Ohio State ranks as the second highest single-game performance in U-M history, as follows:
During his career in the NFL, Biakabutuka was often injured. He never played more than 12 games in a single season . For his career he played in 50 games over 6 seasons. Over that stretch he totaled 3319 yards from scrimmage and scored 17 touchdowns. As a member of the Carolina Panthers, Biakabutuka became the first running back to record two touchdown runs of 60 or more yards in the same game.