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WBP4

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WBP4
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesWBP4, FBP21, WW domain binding protein 4
External IDsOMIM: 604981; MGI: 109568; HomoloGene: 38287; GeneCards: WBP4; OMA:WBP4 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_007187

NM_018765

RefSeq (protein)

NP_009118

NP_061235

Location (UCSC)Chr 13: 41.06 – 41.08 MbChr 14: 79.7 – 79.72 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

WW domain-binding protein 4 is a protein that in humans is encoded by the WBP4 gene.[5][6]

This gene encodes WW domain-containing binding protein 4. The WW domain represents a small and compact globular structure that interacts with proline-rich ligands. This encoded protein is a general spliceosomal protein that may play a role in cross-intron bridging of U1 and U2 snRNPs in the spliceosomal complex A.[6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000120688Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022023Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Bedford MT, Reed R, Leder P (Sep 1998). "WW domain-mediated interactions reveal a spliceosome-associated protein that binds a third class of proline-rich motif: the proline glycine and methionine-rich motif". Proc Natl Acad Sci U S A. 95 (18): 10602–7. doi:10.1073/pnas.95.18.10602. PMC 27941. PMID 9724750.
  6. ^ a b "Entrez Gene: WBP4 WW domain binding protein 4 (formin binding protein 21)".

Further reading