The 2010 Women's Professional Soccer All-Star Game was the second WPS All-Star Game, taking place on June 30, 2010. Thirty-six players were divided into two teams with the top US vote-getter (Abby Wambach) and the top international vote-getter (Marta) as captains. Marta's XI defeated Abby's XI by five to two.
Twenty-two of the thirty-six WPS All-Stars were chosen by vote. 25% of the total vote came from fans voting online, 25% from media, 25% from coaches (who were prohibited from voting for their team's players), and 25% from players. The results of the voting were released on June 9, 2010. 
The remaining fourteen players on the All-Star rosters were selected by WPS Commissioner Tonya Antonucci and the two All-Star coaches Albertin Montoya and Paul Riley, who were the coaches of the two teams topping the standings at the time, on June 14.