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| birth_name = Фёдор Урнов
| birth_name = Фёдор Урнов
| birth_place = [[Russian SFSR]]
| birth_place = [[Russian SFSR]]
| workplaces = [[UC Berkeley]]
| alma_mater = {{unbulleted list|[[Moscow State University]]|[[Brown University]]}}
| alma_mater = {{unbulleted list|[[Moscow State University]]|[[Brown University]]}}
| academic_advisors = [[Susan Gerbi]]
| academic_advisors = [[Susan Gerbi]]
| known_for = [[Genome editing]]
}}
}}


'''Fyodor Dmitriyevich Urnov<ref>{{Cite thesis|title=The origin of DNA amplification in Sciara coprophila DNA puff II/9A: nucleotide sequence, chromatin structure, and protein-DNA interactions|url=https://www.worldcat.org/title/origin-of-dna-amplification-in-sciara-coprophila-dna-puff-ii9a-nucleotide-sequence-chromatin-structure-and-protein-dna-interactions/oclc/83539763|date=1996|language=English|first=Fyodor Dmitriyevich|last=Urnov}}</ref>''' ({{Lang-ru|Фёдор Дми́триевич Урнов}}) is Russian-born [[Biomedicine|biomedical]] researcher and expert in [[genome editing]]. He is a Professor of Genetics, [[Genomics]], and Development at the [[University of California, Berkeley]] and Director of the Center for Translational Genomics at the university's [[Innovative Genomics Institute]].<ref name=":0">{{Cite web|title=Fyodor Urnov Appointed IGI Scientific Director of Technology and Translation|url=https://innovativegenomics.org/news/fyodor-urnov-appointed/|access-date=2022-02-05|website=Innovative Genomics Institute (IGI)|language=en-US}}</ref><ref>{{Cite web|title=Fyodor Urnov {{!}} Research UC Berkeley|url=https://vcresearch.berkeley.edu/faculty/fyodor-urnov|access-date=2022-02-05|website=vcresearch.berkeley.edu}}</ref> He is considered a pioneering figure in the field of genome editing and his work has been cited widely.<ref>{{Cite web|last=David|first=Cyranoski|title=DNA Editing of Human Embryos Alarms Scientists|url=https://www.scientificamerican.com/article/dna-editing-of-human-embryos-alarms-scientists/|access-date=2022-02-06|website=[[Scientific American]]|language=en}}</ref><ref>{{Cite journal|last=Sheridan|first=Cormac|date=2021-12-15|title=Off-the-shelf, gene-edited CAR-T cells forge ahead, despite safety scare|url=https://www.nature.com/articles/d41587-021-00027-1|journal=Nature Biotechnology|language=en|volume=40|issue=1|pages=5–8|doi=10.1038/d41587-021-00027-1}}</ref><ref>{{Cite web|title=World's Most Influential Scientific Minds: 2014|url=https://pharmacy.umich.edu/sites/default/files/worlds-most-influential-scientific-minds-2014.pdf|website=[[Thomson Reuters]]|page=16}}</ref>
'''Fyodor Dmitriyevich Urnov<ref>{{Cite thesis|title=The origin of DNA amplification in Sciara coprophila DNA puff II/9A: nucleotide sequence, chromatin structure, and protein-DNA interactions|url=https://www.worldcat.org/title/origin-of-dna-amplification-in-sciara-coprophila-dna-puff-ii9a-nucleotide-sequence-chromatin-structure-and-protein-dna-interactions/oclc/83539763|date=1996|language=English|first=Fyodor Dmitriyevich|last=Urnov}}</ref>''' ({{Lang-ru|Фёдор Дми́триевич Урнов}}) is Russian-born [[Biomedicine|biomedical]] researcher and expert in [[genome editing]]. He is a Professor of Genetics, [[Genomics]], and Development at the [[University of California, Berkeley]] and Director of the Center for Translational Genomics at the university's [[Innovative Genomics Institute]].<ref name=":0">{{Cite web|title=Fyodor Urnov Appointed IGI Scientific Director of Technology and Translation|url=https://innovativegenomics.org/news/fyodor-urnov-appointed/|access-date=2022-02-05|website=Innovative Genomics Institute (IGI)|language=en-US}}</ref><ref>{{Cite web|title=Fyodor Urnov {{!}} Research UC Berkeley|url=https://vcresearch.berkeley.edu/faculty/fyodor-urnov|access-date=2022-02-05|website=vcresearch.berkeley.edu}}</ref> In 2005 Urnov and his colleagues coined the term "genome editing"<ref>{{Cite book|last=Morange|first=Michel|url=https://books.google.com/books?id=HOPfDwAAQBAJ&newbks=0&hl=en|title=The Black Box of Biology: A History of the Molecular Revolution|date=2020-06-09|publisher=Harvard University Press|isbn=978-0-674-24525-9|pages=307|language=en}}</ref> and demonstrated the first use of [[Zinc finger nuclease|ZFNs]] to edit DNA in human cells.<ref name=":2">{{Cite journal|last=Friedrichs|first=Steffi|last2=Takasu|first2=Yoko|last3=Kearns|first3=Peter|last4=Dagallier|first4=Bertrand|last5=Oshima|first5=Ryudai|last6=Schofield|first6=Janet|last7=Moreddu|first7=Catherine|date=2019-08-01|title=Meeting report of the OECD conference on “Genome Editing: Applications in Agriculture—Implications for Health, Environment and Regulation”|url=https://doi.org/10.1007/s11248-019-00154-1|journal=Transgenic Research|language=en|volume=28|issue=3|pages=419–463|doi=10.1007/s11248-019-00154-1|issn=1573-9368|pmc=PMC6647521|pmid=31309374}}</ref><ref>{{Cite journal|last=Corbyn|first=Zoë|date=2015-12|title=Research: Biology's big hit|url=https://www.nature.com/articles/528S4a|journal=Nature|language=en|volume=528|issue=7580|pages=S4–S5|doi=10.1038/528S4a|issn=1476-4687}}</ref>
Urnov is considered a pioneering figure in the field of genome editing<ref name=":2" /> and his work has been cited widely.<ref>{{Cite web|last=David|first=Cyranoski|title=DNA Editing of Human Embryos Alarms Scientists|url=https://www.scientificamerican.com/article/dna-editing-of-human-embryos-alarms-scientists/|access-date=2022-02-06|website=[[Scientific American]]|language=en}}</ref><ref>{{Cite journal|last=Sheridan|first=Cormac|date=2021-12-15|title=Off-the-shelf, gene-edited CAR-T cells forge ahead, despite safety scare|url=https://www.nature.com/articles/d41587-021-00027-1|journal=Nature Biotechnology|language=en|volume=40|issue=1|pages=5–8|doi=10.1038/d41587-021-00027-1}}</ref><ref>{{Cite web|title=World's Most Influential Scientific Minds: 2014|url=https://pharmacy.umich.edu/sites/default/files/worlds-most-influential-scientific-minds-2014.pdf|website=[[Thomson Reuters]]|page=16}}</ref>


== Early life and education ==
== Early life and education ==
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After graduating, Urnov worked with DNA in the laboratory of [[Alan Wolffe]] at the [[National Institutes of Health]]. In 2000, Urnov followed Wolffe to [[Sangamo Therapeutics]] where he had been recruited as Chief Scientific Officer. Shortly after moving to the [[San Francisco Bay Area]], Urnov was offered an [[Adjunct professor|adjunct]] position as a lecturer at the University of California, Berkeley.<ref name=":1" />
After graduating, Urnov worked with DNA in the laboratory of [[Alan Wolffe]] at the [[National Institutes of Health]]. In 2000, Urnov followed Wolffe to [[Sangamo Therapeutics]] where he had been recruited as Chief Scientific Officer. Shortly after moving to the [[San Francisco Bay Area]], Urnov was offered an [[Adjunct professor|adjunct]] position as a lecturer at the University of California, Berkeley.<ref name=":1" />


In 2019 he joined UC Berkeley as Professor of Genetics, Genomics, and Development and Director of the Center for Translational Genomics at the [[Innovative Genomics Institute]].<ref name=":0" /><ref>{{Cite web|date=2019-11-05|title=Fall 2019 New Faculty Profiles|url=http://mcb.berkeley.edu/news-and-events/transcript/fall-2019-new-faculty-profiles|access-date=2022-02-05|website=Molecular and Cell Biology|language=en}}</ref>
In 2019 Urnov joined UC Berkeley as Professor of Genetics, Genomics, and Development and Director of the Center for Translational Genomics at the [[Innovative Genomics Institute]].<ref name=":0" /><ref>{{Cite web|date=2019-11-05|title=Fall 2019 New Faculty Profiles|url=http://mcb.berkeley.edu/news-and-events/transcript/fall-2019-new-faculty-profiles|access-date=2022-02-05|website=Molecular and Cell Biology|language=en}}</ref>
[[File:Fyodor_Urnov_on_the_Nobel_Prize_for_Jennifer_Doudna_0m0s.jpg|thumb|Urnov in a 2020 interview]]


== References ==
== References ==

Revision as of 00:58, 25 February 2022

Fyodor Urnov
Born
Фёдор Урнов

Russian SFSR
Alma mater
Known forGenome editing
Scientific career
InstitutionsUC Berkeley
Academic advisorsSusan Gerbi

Fyodor Dmitriyevich Urnov[1] (Russian: Фёдор Дми́триевич Урнов) is Russian-born biomedical researcher and expert in genome editing. He is a Professor of Genetics, Genomics, and Development at the University of California, Berkeley and Director of the Center for Translational Genomics at the university's Innovative Genomics Institute.[2][3] In 2005 Urnov and his colleagues coined the term "genome editing"[4] and demonstrated the first use of ZFNs to edit DNA in human cells.[5][6]

Urnov is considered a pioneering figure in the field of genome editing[5] and his work has been cited widely.[7][8][9]

Early life and education

Fyodor Urnov was born in Soviet Russia to a linguist mother and a literary critic father. He was raised in Moscow. Urnov's father frequently purchased him books; on his 12th birthday, Urnov received a copy of James D. Watson's book The Double Helix. The book helped to spark his early interest in life sciences.[10]

Urnov attended Moscow State University, where he received his undergraduate degree in biology in 1990. Following the fall of the Iron Curtain, Urnov applied to graduate schools in the United States. He attended Brown University for doctoral studies where he worked as a researcher in the laboratory of Susan Gerbi.[10] He received his Ph.D. from Brown in 1996.

After graduating, Urnov worked with DNA in the laboratory of Alan Wolffe at the National Institutes of Health. In 2000, Urnov followed Wolffe to Sangamo Therapeutics where he had been recruited as Chief Scientific Officer. Shortly after moving to the San Francisco Bay Area, Urnov was offered an adjunct position as a lecturer at the University of California, Berkeley.[10]

In 2019 Urnov joined UC Berkeley as Professor of Genetics, Genomics, and Development and Director of the Center for Translational Genomics at the Innovative Genomics Institute.[2][11]

Urnov in a 2020 interview

References

  1. ^ Urnov, Fyodor Dmitriyevich (1996). The origin of DNA amplification in Sciara coprophila DNA puff II/9A: nucleotide sequence, chromatin structure, and protein-DNA interactions (Thesis).
  2. ^ a b "Fyodor Urnov Appointed IGI Scientific Director of Technology and Translation". Innovative Genomics Institute (IGI). Retrieved 2022-02-05.
  3. ^ "Fyodor Urnov | Research UC Berkeley". vcresearch.berkeley.edu. Retrieved 2022-02-05.
  4. ^ Morange, Michel (2020-06-09). The Black Box of Biology: A History of the Molecular Revolution. Harvard University Press. p. 307. ISBN 978-0-674-24525-9.
  5. ^ a b Friedrichs, Steffi; Takasu, Yoko; Kearns, Peter; Dagallier, Bertrand; Oshima, Ryudai; Schofield, Janet; Moreddu, Catherine (2019-08-01). "Meeting report of the OECD conference on "Genome Editing: Applications in Agriculture—Implications for Health, Environment and Regulation"". Transgenic Research. 28 (3): 419–463. doi:10.1007/s11248-019-00154-1. ISSN 1573-9368. PMC 6647521. PMID 31309374.{{cite journal}}: CS1 maint: PMC format (link)
  6. ^ Corbyn, Zoë (2015-12). "Research: Biology's big hit". Nature. 528 (7580): S4–S5. doi:10.1038/528S4a. ISSN 1476-4687. {{cite journal}}: Check date values in: |date= (help)
  7. ^ David, Cyranoski. "DNA Editing of Human Embryos Alarms Scientists". Scientific American. Retrieved 2022-02-06.
  8. ^ Sheridan, Cormac (2021-12-15). "Off-the-shelf, gene-edited CAR-T cells forge ahead, despite safety scare". Nature Biotechnology. 40 (1): 5–8. doi:10.1038/d41587-021-00027-1.
  9. ^ "World's Most Influential Scientific Minds: 2014" (PDF). Thomson Reuters. p. 16.
  10. ^ a b c "Devoted to DNA". www.asbmb.org. Retrieved 2022-02-05.
  11. ^ "Fall 2019 New Faculty Profiles". Molecular and Cell Biology. 2019-11-05. Retrieved 2022-02-05.

External links

Retrieved from "https://en.wikipedia.org/w/index.php?title=Fyodor_Urnov&oldid=1073851165"