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[[File:MRI Slices - 2007 and 2014 of astrocytoma patient - Steven Keating.jpg|thumb|[[Magnetic resonance imaging|MRI]] scans of a patient with [[astrocytoma]], showing the tumor's progression between the [[incidentaloma|incidental finding]] in 2007 and the onset of phenotypical changes in 2014.]]
[[File:MRI Slices - 2007 and 2014 of astrocytoma patient - Steven Keating.jpg|thumb|[[Magnetic resonance imaging|MRI]] scans of a patient with [[astrocytoma]], showing the tumor's progression between the [[incidentaloma|incidental finding]] in 2007 and the onset of phenotypical changes in 2014.]]
'''Tumor progression''' is the third and last phase in [[tumor]] development. This phase is characterised by increased growth speed and invasiveness of the tumor cells. As a result of the progression, phenotypical changes occur and the tumor becomes more aggressive and acquires greater malignant potential. Together with the progression, more and more [[aneuploidy]] occurs. This may be evident as nuclear polymorphism.
'''Tumor progression''' is the third and last phase in [[tumor]] development.<ref>{{cite book | vauthors = Compton C | chapter = Cancer initiation, promotion, and progression and the acquisition of key behavioral traits. | title = Cancer: The Enemy from Within | date = 2020 | pages = 25-48 | publisher = Springer | location = Cham | doi = 10.1007/978-3-030-40651-6_2 }}</ref> This phase is characterised by increased growth speed and invasiveness of the tumor cells. As a result of the progression, phenotypical changes occur and the tumor becomes more aggressive and acquires greater malignant potential. Together with the progression, more and more [[aneuploidy]] occurs. This may be evident as nuclear polymorphism.


==See also==
==See also==
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==References==
==References==
{{Reflist}}

== External links ==
* [http://www.cancer.gov/dictionary?CdrID=44078 Progression] entry in the public domain NCI Dictionary of Cancer Terms
* [http://www.cancer.gov/dictionary?CdrID=44078 Progression] entry in the public domain NCI Dictionary of Cancer Terms



Revision as of 11:58, 20 June 2022

MRI scans of a patient with astrocytoma, showing the tumor's progression between the incidental finding in 2007 and the onset of phenotypical changes in 2014.

Tumor progression is the third and last phase in tumor development.[1] This phase is characterised by increased growth speed and invasiveness of the tumor cells. As a result of the progression, phenotypical changes occur and the tumor becomes more aggressive and acquires greater malignant potential. Together with the progression, more and more aneuploidy occurs. This may be evident as nuclear polymorphism.

See also

References

  1. ^ Compton C (2020). "Cancer initiation, promotion, and progression and the acquisition of key behavioral traits.". Cancer: The Enemy from Within. Cham: Springer. pp. 25–48. doi:10.1007/978-3-030-40651-6_2.

External links

  • Progression entry in the public domain NCI Dictionary of Cancer Terms

Public Domain This article incorporates public domain material from Dictionary of Cancer Terms. U.S. National Cancer Institute.