FLI1

FLI1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1FLI, 1X66, 2YTU, 5E8G, 5E8I
Identifiers
Aliases	FLI1, EWSR2, SIC-1, Fli-1 proto-oncogene, ETS transcription factor, BDPLT21, FLI-1
External IDs	OMIM: 193067; MGI: 95554; HomoloGene: 55624; GeneCards: FLI1; OMA:FLI1 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11q24.3 Start 128,686,535 bp End 128,813,267 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9 A4|9 17.74 cM Start 32,333,500 bp End 32,454,157 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in monocyte blood spleen bone marrow cells trabecular bone appendix lymph node right lung upper lobe of left lung visceral pleura Top expressed in dermis spleen left lung lobe blood abdominal wall body of femur intercostal muscle thymus subcutaneous adipose tissue atrioventricular valve More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein binding RNA polymerase II cis-regulatory region sequence-specific DNA binding chromatin binding sequence-specific DNA binding DNA-binding transcription factor activity DNA binding DNA-binding transcription activator activity, RNA polymerase II-specific DNA-binding transcription factor activity, RNA polymerase II-specific Cellular component nucleus cytosol nuclear body Biological process megakaryocyte development positive regulation of transcription by RNA polymerase II transcription by RNA polymerase II hemostasis regulation of transcription, DNA-templated regulation of transcription by RNA polymerase II cell differentiation animal organ morphogenesis blood circulation transcription, DNA-templated positive regulation of transcription, DNA-templated Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 2313 14247 Ensembl ENSG00000151702 ENSMUSG00000016087 UniProt Q01543 P26323 RefSeq (mRNA) NM_001167681 NM_001271010 NM_001271012 NM_002017 NM_008026 RefSeq (protein) NP_001161153 NP_001257939 NP_001257941 NP_002008 NP_001161153.1 NP_032052 Location (UCSC) Chr 11: 128.69 – 128.81 Mb Chr 9: 32.33 – 32.45 Mb PubMed search
Wikidata
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Friend leukemia virus integration 1, also known as FLI1, is a human gene.