Peroxiredoxin 1

PRDX1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2RII, 3HY2, 4XCS
Identifiers
Aliases	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2, Peroxiredoxin 1
External IDs	OMIM: 176763 MGI: 99523 HomoloGene: 99789 GeneCards: PRDX1
Gene location (Human) Chr. Chromosome 1 (human) Band 1p34.1 Start 45,510,914 bp End 45,542,732 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4 D1|4 53.28 cM Start 116,542,741 bp End 116,558,019 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in right lobe of thyroid gland left lobe of thyroid gland palpebral conjunctiva ganglionic eminence gums oral cavity islet of Langerhans right adrenal gland left adrenal gland right lung Top expressed in vas deferens primitive streak iris otic placode abdominal wall right lung lobe Paneth cell cervix olfactory epithelium mucous cell of stomach More reference expression data BioGPS More reference expression data
Gene ontology Molecular function antioxidant activity protein binding peroxiredoxin activity identical protein binding oxidoreductase activity thioredoxin peroxidase activity peroxidase activity RNA binding cadherin binding Cellular component cytoplasm cytosol melanosome myelin sheath mitochondrion extracellular exosome nucleus extracellular matrix extracellular space Biological process skeletal system development removal of superoxide radicals response to oxidative stress retina homeostasis erythrocyte homeostasis hydrogen peroxide catabolic process cell population proliferation regulation of stress-activated MAPK cascade natural killer cell mediated cytotoxicity cell redox homeostasis natural killer cell activation response to reactive oxygen species cellular response to oxidative stress regulation of NIK/NF-kappaB signaling leukocyte activation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 5052 18477 Ensembl ENSG00000117450 ENSMUSG00000028691 UniProt Q06830 P35700 RefSeq (mRNA) NM_181697 NM_001202431 NM_002574 NM_181696 NM_011034 RefSeq (protein) NP_001189360 NP_002565 NP_859047 NP_859048 NP_035164 Location (UCSC) Chr 1: 45.51 – 45.54 Mb Chr 4: 116.54 – 116.56 Mb PubMed search
Wikidata
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Peroxiredoxin 1, also known as PRDX1, is a human gene.