Peroxiredoxin 2

PRDX2
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1QMV
Identifiers
Aliases	PRDX2, HEL-S-2a, NKEF-B, NKEFB, PRP, PRX2, PRXII, PTX1, TDPX1, TPX1, TSA, Peroxiredoxin 2
External IDs	OMIM: 600538 MGI: 109486 HomoloGene: 21182 GeneCards: PRDX2
Gene location (Human) Chr. Chromosome 19 (human) Band 19p13.13 Start 12,796,820 bp End 12,801,800 bp
Gene location (Mouse) Chr. Chromosome 8 (mouse) Band 8 C3|8 41.4 cM Start 85,696,216 bp End 85,701,463 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in trabecular bone external globus pallidus pons right ventricle left adrenal gland superior vestibular nucleus embryo prefrontal cortex left ventricle ganglionic eminence Top expressed in superior frontal gyrus lip yolk sac motor neuron maxillary prominence aortic valve secondary oocyte neural tube ascending aorta trigeminal ganglion More reference expression data BioGPS More reference expression data
Gene ontology Molecular function oxidoreductase activity antioxidant activity peroxiredoxin activity peroxidase activity protein binding thioredoxin peroxidase activity Cellular component cytoplasm extracellular exosome cytosol Biological process regulation of apoptotic process negative regulation of apoptotic process hydrogen peroxide catabolic process cell redox homeostasis response to oxidative stress cellular response to oxidative stress removal of superoxide radicals respiratory burst involved in inflammatory response regulation of hydrogen peroxide metabolic process positive regulation of blood coagulation negative regulation of lipopolysaccharide-mediated signaling pathway negative regulation of NF-kappaB transcription factor activity response to lipopolysaccharide T cell proliferation hydrogen peroxide metabolic process negative regulation of T cell differentiation thymus development homeostasis of number of cells negative regulation of reactive oxygen species metabolic process negative regulation of extrinsic apoptotic signaling pathway negative regulation of extrinsic apoptotic signaling pathway in absence of ligand leukocyte activation Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 7001 21672 Ensembl ENSG00000167815 ENSMUSG00000005161 UniProt P32119 Q61171 RefSeq (mRNA) NM_181738 NM_005809 NM_181737 NM_011563 NM_001317385 RefSeq (protein) NP_005800 NP_001304314 NP_035693 Location (UCSC) Chr 19: 12.8 – 12.8 Mb Chr 8: 85.7 – 85.7 Mb PubMed search
Wikidata
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Peroxiredoxin 2, also known as PRDX2, is a human gene.