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Revision as of 12:34, 2 November 2010

mir-143
Identifiers
Symbolmir-143
RfamRF00683
miRBase familyMIPF0000094
Other data
RNA typemicroRNA
Domain(s)Eukaryota;
PDB structuresPDBe

In molecular biology mir-143 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by a several mechanisms.

See also

Further reading

  1. ^ Kitade Y, Akao Y (2010). "MicroRNAs and Their Therapeutic Potential for Human Diseases: MicroRNAs, miR-143 and -145, Function as Anti-oncomirs and the Application of Chemically Modified miR-143 as an Anti-cancer Drug". J Pharmacol Sci. PMID 20953119.
  2. ^ Zhang H, Cai X, Wang Y, Tang H, Tong D, Ji F (2010). "microRNA-143, down-regulated in osteosarcoma, promotes apoptosis and suppresses tumorigenicity by targeting Bcl-2". Oncol Rep. 24 (5): 1363–9. PMID 20878132.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ Miyasaka KY, Kida YS, Banjo T, Ueki Y, Nagayama K, Matsumoto T, Sato M, Ogura T (2010). "Heartbeat regulates cardiogenesis by suppressing retinoic acid signaling via expression of miR-143". Mech Dev. PMID 20869435.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. ^ Kulda V, Pesta M, Topolcan O, Liska V, Treska V, Sutnar A, Rupert K, Ludvikova M, Babuska V, Holubec L, Cerny R (2010). "Relevance of miR-21 and miR-143 expression in tissue samples of colorectal carcinoma and its liver metastases". Cancer Genet Cytogenet. 200 (2): 154–60. PMID 20620599.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  5. ^ Yang Y, Chaerkady R, Kandasamy K, Huang TC, Selvan LD, Dwivedi SB, Kent OA, Mendell JT, Pandey A (2010). "Identifying targets of miR-143 using a SILAC-based proteomic approach". Mol Biosyst. 6 (10): 1873–82. PMID 20544124.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  6. ^ Iio A, Nakagawa Y, Hirata I, Naoe T, Akao Y (2010). "Identification of non-coding RNAs embracing microRNA-143/145 cluster". Mol Cancer. 9: 136. PMID 20525177.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  7. ^ Wang X, Hu G, Zhou J (2010). "Repression of versican expression by microRNA-143". J Biol Chem. 285 (30): 23241–50. PMID 20489207.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  8. ^ Deacon DC, Nevis KR, Cashman TJ, Zhou Y, Zhao L, Washko D, Guner-Ataman B, Burns CG, Burns CE (2010). "The miR-143-adducin3 pathway is essential for cardiac chamber morphogenesis". Development. 137 (11): 1887–96. PMID 20460367.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  9. ^ Gao W, Yu Y, Cao H, Shen H, Li X, Pan S, Shu Y (2010). "Deregulated expression of miR-21, miR-143 and miR-181a in non small cell lung cancer is related to clinicopathologic characteristics or patient prognosis". Biomed Pharmacother. 64 (6): 399–408. PMID 20363096.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  10. ^ Akao Y, Nakagawa Y, Hirata I, Iio A, Itoh T, Kojima K, Nakashima R, Kitade Y, Naoe T (2010). "Role of anti-oncomirs miR-143 and -145 in human colorectal tumors". Cancer Gene Ther. 17 (6): 398–408. PMID 20094072.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  11. ^ Trakooljul N, Hicks JA, Liu HC (2010). "Identification of target genes and pathways associated with chicken microRNA miR-143". Anim Genet. 41 (4): 357–64. PMID 20064147.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  12. ^ Clapé C, Fritz V, Henriquet C, Apparailly F, Fernandez PL, Iborra F, Avancès C, Villalba M, Culine S, Fajas L (2009). "miR-143 interferes with ERK5 signaling, and abrogates prostate cancer progression in mice". PLoS One. 4 (10): e7542. PMID 19855844.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  13. ^ Borralho PM, Kren BT, Castro RE, da Silva IB, Steer CJ, Rodrigues CM (2009). "MicroRNA-143 reduces viability and increases sensitivity to 5-fluorouracil in HCT116 human colorectal cancer cells". FEBS J. 276 (22): 6689–700. PMID 19843160.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  14. ^ Elia L, Quintavalle M, Zhang J, Contu R, Cossu L, Latronico MV, Peterson KL, Indolfi C, Catalucci D, Chen J, Courtneidge SA, Condorelli G (2009). "The knockout of miR-143 and -145 alters smooth muscle cell maintenance and vascular homeostasis in mice: correlates with human disease". Cell Death Differ. 16 (12): 1590–8. PMID 19816508.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  15. ^ Xin M, Small EM, Sutherland LB, Qi X, McAnally J, Plato CF, Richardson JA, Bassel-Duby R, Olson EN (2009). "MicroRNAs miR-143 and miR-145 modulate cytoskeletal dynamics and responsiveness of smooth muscle cells to injury". Genes Dev. 23 (18): 2166–78. PMID 19720868.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  16. ^ Zhang R, Wang L, Yang AG (2009). "Is microRNA-143 really a turncoat of tumor suppressor microRNA in hepatitis B virus-related hepatocellular carcinoma?". Hepatology. 50 (3): 987, author reply 987-8. PMID 19670426.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  17. ^ Ng EK, Tsang WP, Ng SS, Jin HC, Yu J, Li JJ, Röcken C, Ebert MP, Kwok TT, Sung JJ (2009). "MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer". Br J Cancer. 101 (4): 699–706. PMID 19638978.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  18. ^ Cordes KR, Sheehy NT, White MP, Berry EC, Morton SU, Muth AN, Lee TH, Miano JM, Ivey KN, Srivastava D (2009). "miR-145 and miR-143 regulate smooth muscle cell fate and plasticity". Nature. 460 (7256): 705–10. PMID 19578358.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  19. ^ Zhang X, Liu S, Hu T, Liu S, He Y, Sun S (2009). "Up-regulated microRNA-143 transcribed by nuclear factor kappa B enhances hepatocarcinoma metastasis by repressing fibronectin expression". Hepatology. 50 (2): 490–9. PMID 19472311.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  20. ^ Akao Y, Nakagawa Y, Iio A, Naoe T (2009). "Role of microRNA-143 in Fas-mediated apoptosis in human T-cell leukemia Jurkat cells". Leuk Res. 33 (11): 1530–8. PMID 19464056.{{cite journal}}: CS1 maint: multiple names: authors list (link)

External links

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