MiR-155: Difference between revisions

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{{Infobox rfam
| Name = mir-155
| image =
| width =
| caption =
| Symbol = mir-155
| AltSymbols =
| Rfam = RF00731
| miRBase_family = MIPF0000157
| RNA_type = [[microRNA]]
| Tax_domain = ''[[Eukaryote|Eukaryota]];''
| HGNCid =
| OMIM =
}}


In molecular biology, '''mir-155 microRNA''' is a short [[non-coding RNA|RNA]] molecule. [[MicroRNA]]s function to regulate the expression levels of other genes by a several mechanisms.
In molecular biology, '''mir-155 microRNA''' is a short [[non-coding RNA|RNA]] molecule. [[MicroRNA]]s function to regulate the expression levels of other genes by a several mechanisms.


== See also ==
* [[MicroRNA]]

==Further reading==
<div style='display:none'>
<ref name="pmid21030878">{{cite journal |author=Huang RS, Hu GQ, Lin B, Lin ZY, Sun CC |title=MicroRNA-155 Silencing Enhances Inflammatory Response and Lipid Uptake in Oxidized Low-Density Lipoprotein-Stimulated Human THP-1 Macrophages. |journal=J Investig Med |volume= |issue= |pages= |year=2010 |pmid=21030878}}</ref>
<ref name="pmid20966899">{{cite journal |author=Ceolotto G, Papparella I, Bortoluzzi A, Strapazzon G, Ragazzo F, Bratti P, Fabricio AS, Squarcina E, Gion M, Palatini P, Semplicini A |title=Interplay Between miR-155, AT1R A1166C Polymorphism, and AT1R Expression in Young Untreated Hypertensives. |journal=Am J Hypertens |volume= |issue= |pages= |year=2010 |pmid=20966899}}</ref>
<ref name="pmid20952466">{{cite journal |author=Wang G, Tam LS, Li EK, Kwan BC, Chow KM, Luk CC, Li PK, Szeto CC |title=Serum and Urinary Cell-free MiR-146a and MiR-155 in Patients with Systemic Lupus Erythematosus. |journal=J Rheumatol |volume= |issue= |pages= |year=2010 |pmid=20952466}}</ref>
<ref name="pmid20950585">{{cite journal |author=Kutty RK, Nagineni CN, Samuel W, Vijayasarathy C, Hooks JJ, Redmond TM |title=Inflammatory cytokines regulate microRNA-155 expression in human retinal pigment epithelial cells by activating JAK/STAT pathway. |journal=Biochem Biophys Res Commun |volume= |issue= |pages= |year=2010 |pmid=20950585}}</ref>
<ref name="pmid20948191">{{cite journal |author=Imaizumi T, Tanaka H, Tajima A, Yokono Y, Matsumiya T, Yoshida H, Tsuruga K, Aizawa-Yashiro T, Hayakari R, Inoue I, Ito E, Satoh K |title=IFN-γ and TNF-α Synergistically Induce microRNA-155 Which Regulates TAB2/IP-10 Expression in Human Mesangial Cells. |journal=Am J Nephrol |volume=32 |issue=5 |pages=462-468 |year=2010 |pmid=20948191}}</ref>
<ref name="pmid20947507">{{cite journal |author=Thompson RC, Herscovitch M, Zhao I, Ford TJ, Gilmore TD |title=NF-{kappa}B down-regulates expression of the B-lymphoma marker CD10 through a miR-155/PU.1 pathway. |journal=J Biol Chem |volume= |issue= |pages= |year=2010 |pmid=20947507}}</ref>
<ref name="pmid20937844">{{cite journal |author=Wang P, Hou J, Lin L, Wang C, Liu X, Li D, Ma F, Wang Z, Cao X |title=Inducible microRNA-155 Feedback Promotes Type I IFN Signaling in Antiviral Innate Immunity by Targeting Suppressor of Cytokine Signaling 1. |journal=J Immunol |volume= |issue= |pages= |year=2010 |pmid=20937844}}</ref>
<ref name="pmid20888269">{{cite journal |author=O'Connell RM, Kahn D, Gibson WS, Round JL, Scholz RL, Chaudhuri AA, Kahn ME, Rao DS, Baltimore D |title=MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development. |journal=Immunity |volume=33 |issue=4 |pages=607-19 |year=2010 |pmid=20888269}}</ref>
<ref name="pmid20871480">{{cite journal |author=Xia QS, Ishigaki Y, Zhao X, Shimasaki T, Nakajima H, Nakagawa H, Takegami T, Chen ZH, Motoo Y |title=Human SMG-1 is Involved in Gemcitabine-Induced Primary microRNA-155/BIC Up-Regulation in Human Pancreatic Cancer PANC-1 Cells. |journal=Pancreas |volume= |issue= |pages= |year=2010 |pmid=20871480}}</ref>
<ref name="pmid20852130">{{cite journal |author=Zhou H, Huang X, Cui H, Luo X, Tang Y, Chen S, Wu L, Shen N |title=miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells. |journal=Blood |volume= |issue= |pages= |year=2010 |pmid=20852130}}</ref>
<ref name="pmid20844043">{{cite journal |author=Linnstaedt SD, Gottwein E, Skalsky RL, Luftig MA, Cullen BR |title=Virally Induced Cellular MicroRNA miR-155 Plays a Key Role in B-Cell Immortalization by Epstein-Barr Virus. |journal=J Virol |volume=84 |issue=22 |pages=11670-8 |year=2010 |pmid=20844043}}</ref>
<ref name="pmid20735984">{{cite journal |author=Zheng L, Xu CC, Chen WD, Shen WL, Ruan CC, Zhu LM, Zhu DL, Gao PJ |title=MicroRNA-155 regulates angiotensin II type 1 receptor expression and phenotypic differentiation in vascular adventitial fibroblasts. |journal=Biochem Biophys Res Commun |volume=400 |issue=4 |pages=483-8 |year=2010 |pmid=20735984}}</ref>
<ref name="pmid20673989">{{cite journal |author=Sonkoly E, Janson P, Majuri ML, Savinko T, Fyhrquist N, Eidsmo L, Xu N, Meisgen F, Wei T, Bradley M, Stenvang J, Kauppinen S, Alenius H, Lauerma A, Homey B, Winqvist O, Ståhle M, Pivarcsi A |title=MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4. |journal=J Allergy Clin Immunol |volume=126 |issue=3 |pages=581-9.e1-20 |year=2010 |pmid=20673989}}</ref>
<ref name="pmid20622002">{{cite journal |author=Tili E, Michaille JJ, Adair B, Alder H, Limagne E, Taccioli C, Ferracin M, Delmas D, Latruffe N, Croce CM |title=Resveratrol decreases the levels of miR-155 by upregulating miR-663, a microRNA targeting JunB and JunD. |journal=Carcinogenesis |volume=31 |issue=9 |pages=1561-6 |year=2010 |pmid=20622002}}</ref>
<ref name="pmid20579867">{{cite journal |author=Boesch-Saadatmandi C, Loboda A, Wagner AE, Stachurska A, Jozkowicz A, Dulak J, Döring F, Wolffram S, Rimbach G |title=Effect of quercetin and its metabolites isorhamnetin and quercetin-3-glucuronide on inflammatory gene expression: role of miR-155. |journal=J Nutr Biochem |volume= |issue= |pages= |year=2010 |pmid=20579867}}</ref>
<ref name="pmid20550618">{{cite journal |author=Liu J, van Mil A, Vrijsen K, Zhao J, Gao L, Goumans MJ, Doevendans PA, Sluijter JP |title=MicroRNA-155 prevents necrotic cell death in human cardiomyocyte progenitor cells via targeting RIP1. |journal=J Cell Mol Med |volume= |issue= |pages= |year=2010 |pmid=20550618}}</ref>
<ref name="pmid20548288">{{cite journal |author=Pogribny IP, Starlard-Davenport A, Tryndyak VP, Han T, Ross SA, Rusyn I, Beland FA |title=Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice. |journal=Lab Invest |volume=90 |issue=10 |pages=1437-46 |year=2010 |pmid=20548288}}</ref>
<ref name="pmid20452491">{{cite journal |author=Zhang Y, Diao Z, Su L, Sun H, Li R, Cui H, Hu Y |title=MicroRNA-155 contributes to preeclampsia by down-regulating CYR61. |journal=Am J Obstet Gynecol |volume=202 |issue=5 |pages=466.e1-7 |year=2010 |pmid=20452491}}</ref>
<ref name="pmid20444872">{{cite journal |author=Hu YL, Fong S, Largman C, Shen WF |title=HOXA9 regulates miR-155 in hematopoietic cells. |journal=Nucleic Acids Res |volume=38 |issue=16 |pages=5472-8 |year=2010 |pmid=20444872}}</ref>
<ref name="pmid20435894">{{cite journal |author=McCoy CE, Sheedy FJ, Qualls JE, Doyle SL, Quinn SR, Murray PJ, O'Neill LA |title=IL-10 inhibits miR-155 induction by toll-like receptors. |journal=J Biol Chem |volume=285 |issue=27 |pages=20492-8 |year=2010 |pmid=20435894}}</ref>
<ref name="pmid20427544">{{cite journal |author=Yin Q, Wang X, Fewell C, Cameron J, Zhu H, Baddoo M, Lin Z, Flemington EK |title=MicroRNA miR-155 inhibits bone morphogenetic protein (BMP) signaling and BMP-mediated Epstein-Barr virus reactivation. |journal=J Virol |volume=84 |issue=13 |pages=6318-27 |year=2010 |pmid=20427544}}</ref>
<ref name="pmid20388420">{{cite journal |author=Zhu J, Hu XQ, Guo GL, Zhang Y, Wang OC, You J, Huang QD, Zhang XH |title=[Expression and its clinical significance of miR-155 in human primary breast cancer.] |journal=Zhonghua Wai Ke Za Zhi |volume=48 |issue=3 |pages=205-8 |year=2010 |pmid=20388420}}</ref>
<ref name="pmid20371610">{{cite journal |author=Kong W, He L, Coppola M, Guo J, Esposito NN, Coppola D, Cheng JQ |title=MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer. |journal=J Biol Chem |volume=285 |issue=23 |pages=17869-79 |year=2010 |pmid=20371610}}</ref>
<ref name="pmid20356498">{{cite journal |author=Xia QS, Ishigaki Y, Sun L, Chen R, Motoo Y |title=[Effect of anti-cancer drugs on the expression of BIC/miR-155 in human pancreatic cancer PANC-1 cells] |journal=Zhonghua Yi Xue Za Zhi |volume=90 |issue=2 |pages=123-7 |year=2010 |pmid=20356498}}</ref>
<ref name="pmid20354188">{{cite journal |author=Jiang S, Zhang HW, Lu MH, He XH, Li Y, Gu H, Liu MF, Wang ED |title=MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene. |journal=Cancer Res |volume=70 |issue=8 |pages=3119-27 |year=2010 |pmid=20354188}}</ref>
<ref name="pmid20351277">{{cite journal |author=Valeri N, Gasparini P, Fabbri M, Braconi C, Veronese A, Lovat F, Adair B, Vannini I, Fanini F, Bottoni A, Costinean S, Sandhu SK, Nuovo GJ, Alder H, Gafa R, Calore F, Ferracin M, Lanza G, Volinia S, Negrini M, McIlhatton MA, Amadori D, Fishel R, Croce CM |title=Modulation of mismatch repair and genomic stability by miR-155. |journal=Proc Natl Acad Sci U S A |volume=107 |issue=15 |pages=6982-7 |year=2010 |pmid=20351277}}</ref>
<ref name="pmid20332664">{{cite journal |author=Ryu JK, Hong SM, Karikari CA, Hruban RH, Goggins MG, Maitra A |title=Aberrant MicroRNA-155 expression is an early event in the multistep progression of pancreatic adenocarcinoma. |journal=Pancreatology |volume=10 |issue=1 |pages=66-73 |year=2010 |pmid=20332664}}</ref>
<ref name="pmid20223773">{{cite journal |author=Fabani MM, Abreu-Goodger C, Williams D, Lyons PA, Torres AG, Smith KG, Enright AJ, Gait MJ, Vigorito E |title=Efficient inhibition of miR-155 function in vivo by peptide nucleic acids. |journal=Nucleic Acids Res |volume=38 |issue=13 |pages=4466-75 |year=2010 |pmid=20223773}}</ref>
<ref name="pmid20219467">{{cite journal |author=Tang B, Xiao B, Liu Z, Li N, Zhu ED, Li BS, Xie QH, Zhuang Y, Zou QM, Mao XH |title=Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation. |journal=FEBS Lett |volume=584 |issue=8 |pages=1481-6 |year=2010 |pmid=20219467}}</ref>
<ref name="pmid20209161">{{cite journal |author=Fassi Fehri L, Koch M, Belogolova E, Khalil H, Bolz C, Kalali B, Mollenkopf HJ, Beigier-Bompadre M, Karlas A, Schneider T, Churin Y, Gerhard M, Meyer TF |title=Helicobacter pylori induces miR-155 in T cells in a cAMP-Foxp3-dependent manner. |journal=PLoS One |volume=5 |issue=3 |pages=e9500 |year=2010 |pmid=20209161}}</ref>
<ref name="pmid20201617">{{cite journal |author=Sidorkiewicz M, Grek M, Jozwiak B, Majda-Stanislawska E, Piekarska A, Bartkowiak J |title=Expression of microRNA-155 precursor in peripheral blood mononuclear cells from Hepatitis C patients after antiviral treatment. |journal=Acta Virol |volume=54 |issue=1 |pages=75-8 |year=2010 |pmid=20201617}}</ref>
<ref name="pmid20170545">{{cite journal |author=Gueta K, Molotski N, Gerchikov N, Mor E, Savion S, Fein A, Toder V, Shomron N, Torchinsky A |title=Teratogen-induced alterations in microRNA-34, microRNA-125b and microRNA-155 expression: correlation with embryonic p53 genotype and limb phenotype. |journal=BMC Dev Biol |volume=10 |issue= |pages=20 |year=2010 |pmid=20170545}}</ref>
<ref name="pmid20133617">{{cite journal |author=Rai D, Kim SW, McKeller MR, Dahia PL, Aguiar RC |title=Targeting of SMAD5 links microRNA-155 to the TGF-beta pathway and lymphomagenesis. |journal=Proc Natl Acad Sci U S A |volume=107 |issue=7 |pages=3111-6 |year=2010 |pmid=20133617}}</ref>
<ref name="pmid20041145">{{cite journal |author=Cremer TJ, Ravneberg DH, Clay CD, Piper-Hunter MG, Marsh CB, Elton TS, Gunn JS, Amer A, Kanneganti TD, Schlesinger LS, Butchar JP, Tridandapani S |title=MiR-155 induction by F. novicida but not the virulent F. tularensis results in SHIP down-regulation and enhanced pro-inflammatory cytokine response. |journal=PLoS One |volume=4 |issue=12 |pages=e8508 |year=2009 |pmid=20041145}}</ref>
<ref name="pmid19956200">{{cite journal |author=Forrest AR, Kanamori-Katayama M, Tomaru Y, Lassmann T, Ninomiya N, Takahashi Y, de Hoon MJ, Kubosaki A, Kaiho A, Suzuki M, Yasuda J, Kawai J, Hayashizaki Y, Hume DA, Suzuki H |title=Induction of microRNAs, mir-155, mir-222, mir-424 and mir-503, promotes monocytic differentiation through combinatorial regulation. |journal=Leukemia |volume=24 |issue=2 |pages=460-6 |year=2010 |pmid=19956200}}</ref>
<ref name="pmid19890474">{{cite journal |author=Pedersen IM, Otero D, Kao E, Miletic AV, Hother C, Ralfkiaer E, Rickert RC, Gronbaek K, David M |title=Onco-miR-155 targets SHIP1 to promote TNFalpha-dependent growth of B cell lymphomas. |journal=EMBO Mol Med |volume=1 |issue=5 |pages=288-95 |year=2009 |pmid=19890474}}</ref>
<ref name="pmid19887047">{{cite journal |author=He M, Xu Z, Ding T, Kuang DM, Zheng L |title=MicroRNA-155 regulates inflammatory cytokine production in tumor-associated macrophages via targeting C/EBPbeta. |journal=Cell Mol Immunol |volume=6 |issue=5 |pages=343-52 |year=2009 |pmid=19887047}}</ref>
<ref name="pmid19811312">{{cite journal |author=Tili E, Croce CM, Michaille JJ |title=miR-155: on the crosstalk between inflammation and cancer. |journal=Int Rev Immunol |volume=28 |issue=5 |pages=264-84 |year=2009 |pmid=19811312}}</ref>
<ref name="pmid19777054">{{cite journal |author=Stahl HF, Fauti T, Ullrich N, Bopp T, Kubach J, Rust W, Labhart P, Alexiadis V, Becker C, Hafner M, Weith A, Lenter MC, Jonuleit H, Schmitt E, Mennerich D |title=miR-155 inhibition sensitizes CD4+ Th cells for TREG mediated suppression. |journal=PLoS One |volume=4 |issue=9 |pages=e7158 |year=2009 |pmid=19777054}}</ref>
<ref name="pmid19759154">{{cite journal |author=Bolisetty MT, Dy G, Tam W, Beemon KL |title=Reticuloendotheliosis virus strain T induces miR-155, which targets JARID2 and promotes cell survival. |journal=J Virol |volume=83 |issue=23 |pages=12009-17 |year=2009 |pmid=19759154}}</ref>
<ref name="pmid19711427">{{cite journal |author=Wang B, Majumder S, Nuovo G, Kutay H, Volinia S, Patel T, Schmittgen TD, Croce C, Ghoshal K, Jacob ST |title=Role of microRNA-155 at early stages of hepatocarcinogenesis induced by choline-deficient and amino acid-defined diet in C57BL/6 mice. |journal=Hepatology |volume=50 |issue=4 |pages=1152-61 |year=2009 |pmid=19711427}}</ref>
<ref name="pmid19701459">{{cite journal |author=Pottier N, Maurin T, Chevalier B, Puisségur MP, Lebrigand K, Robbe-Sermesant K, Bertero T, Lino Cardenas CL, Courcot E, Rios G, Fourre S, Lo-Guidice JM, Marcet B, Cardinaud B, Barbry P, Mari B |title=Identification of keratinocyte growth factor as a target of microRNA-155 in lung fibroblasts: implication in epithelial-mesenchymal interactions. |journal=PLoS One |volume=4 |issue=8 |pages=e6718 |year=2009 |pmid=19701459}}</ref>
<ref name="pmid19650740">{{cite journal |author=Xiao B, Liu Z, Li BS, Tang B, Li W, Guo G, Shi Y, Wang F, Wu Y, Tong WD, Guo H, Mao XH, Zou QM |title=Induction of microRNA-155 during Helicobacter pylori infection and its negative regulatory role in the inflammatory response. |journal=J Infect Dis |volume=200 |issue=6 |pages=916-25 |year=2009 |pmid=19650740}}</ref>
<ref name="pmid19596814">{{cite journal |author=Worm J, Stenvang J, Petri A, Frederiksen KS, Obad S, Elmén J, Hedtjärn M, Straarup EM, Hansen JB, Kauppinen S |title=Silencing of microRNA-155 in mice during acute inflammatory response leads to derepression of c/ebp Beta and down-regulation of G-CSF. |journal=Nucleic Acids Res |volume=37 |issue=17 |pages=5784-92 |year=2009 |pmid=19596814}}</ref>
<ref name="pmid19520806">{{cite journal |author=Costinean S, Sandhu SK, Pedersen IM, Tili E, Trotta R, Perrotti D, Ciarlariello D, Neviani P, Harb J, Kauffman LR, Shidham A, Croce CM |title=Src homology 2 domain-containing inositol-5-phosphatase and CCAAT enhancer-binding protein beta are targeted by miR-155 in B cells of Emicro-MiR-155 transgenic mice. |journal=Blood |volume=114 |issue=7 |pages=1374-82 |year=2009 |pmid=19520806}}</ref>
<ref name="pmid19423639">{{cite journal |author=Ruggiero T, Trabucchi M, De Santa F, Zupo S, Harfe BD, McManus MT, Rosenfeld MG, Briata P, Gherzi R |title=LPS induces KH-type splicing regulatory protein-dependent processing of microRNA-155 precursors in macrophages. |journal=FASEB J |volume=23 |issue=9 |pages=2898-908 |year=2009 |pmid=19423639}}</ref>
<ref name="pmid19386588">{{cite journal |author=Martinez-Nunez RT, Louafi F, Friedmann PS, Sanchez-Elsner T |title=MicroRNA-155 modulates the pathogen binding ability of dendritic cells (DCs) by down-regulation of DC-specific intercellular adhesion molecule-3 grabbing non-integrin (DC-SIGN). |journal=J Biol Chem |volume=284 |issue=24 |pages=16334-42 |year=2009 |pmid=19386588}}</ref>
<ref name="pmid19359473">{{cite journal |author=O'Connell RM, Chaudhuri AA, Rao DS, Baltimore D |title=Inositol phosphatase SHIP1 is a primary target of miR-155. |journal=Proc Natl Acad Sci U S A |volume=106 |issue=17 |pages=7113-8 |year=2009 |pmid=19359473}}</ref>
<ref name="pmid19268705">{{cite journal |author=Faraoni I, Antonetti FR, Cardone J, Bonmassar E |title=miR-155 gene: a typical multifunctional microRNA. |journal=Biochim Biophys Acta |volume=1792 |issue=6 |pages=497-505 |year=2009 |pmid=19268705}}</ref>
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<ref name="pmid19193853">{{cite journal |author=Ceppi M, Pereira PM, Dunand-Sauthier I, Barras E, Reith W, Santos MA, Pierre P |title=MicroRNA-155 modulates the interleukin-1 signaling pathway in activated human monocyte-derived dendritic cells. |journal=Proc Natl Acad Sci U S A |volume=106 |issue=8 |pages=2735-40 |year=2009 |pmid=19193853}}</ref>
<ref name="pmid19106647">{{cite journal |author=Habbe N, Koorstra JB, Mendell JT, Offerhaus GJ, Ryu JK, Feldmann G, Mullendore ME, Goggins MG, Hong SM, Maitra A |title=MicroRNA miR-155 is a biomarker of early pancreatic neoplasia. |journal=Cancer Biol Ther |volume=8 |issue=4 |pages=340-6 |year=2009 |pmid=19106647}}</ref>
<ref name="pmid19016736">{{cite journal |author=Jung I, Aguiar RC |title=MicroRNA-155 expression and outcome in diffuse large B-cell lymphoma. |journal=Br J Haematol |volume=144 |issue=1 |pages=138-40 |year=2009 |pmid=19016736}}</ref>
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<ref name="pmid18950466">{{cite journal |author=Romania P, Lulli V, Pelosi E, Biffoni M, Peschle C, Marziali G |title=MicroRNA 155 modulates megakaryopoiesis at progenitor and precursor level by targeting Ets-1 and Meis1 transcription factors. |journal=Br J Haematol |volume=143 |issue=4 |pages=570-80 |year=2008 |pmid=18950466}}</ref>
<ref name="pmid18945769">{{cite journal |author=Zhao Y, Yao Y, Xu H, Lambeth L, Smith LP, Kgosana L, Wang X, Nair V |title=A functional MicroRNA-155 ortholog encoded by the oncogenic Marek's disease virus. |journal=J Virol |volume=83 |issue=1 |pages=489-92 |year=2009 |pmid=18945769}}</ref>
<ref name="pmid18940871">{{cite journal |author=Gatto G, Rossi A, Rossi D, Kroening S, Bonatti S, Mallardo M |title=Epstein-Barr virus latent membrane protein 1 trans-activates miR-155 transcription through the NF-kappaB pathway. |journal=Nucleic Acids Res |volume=36 |issue=20 |pages=6608-19 |year=2008 |pmid=18940871}}</ref>
<ref name="pmid18926796">{{cite journal |author=Rahadiani N, Takakuwa T, Tresnasari K, Morii E, Aozasa K |title=Latent membrane protein-1 of Epstein-Barr virus induces the expression of B-cell integration cluster, a precursor form of microRNA-155, in B lymphoma cell lines. |journal=Biochem Biophys Res Commun |volume=377 |issue=2 |pages=579-83 |year=2008 |pmid=18926796}}</ref>
<ref name="pmid18794355">{{cite journal |author=Kong W, Yang H, He L, Zhao JJ, Coppola D, Dalton WS, Cheng JQ |title=MicroRNA-155 is regulated by the transforming growth factor beta/Smad pathway and contributes to epithelial cell plasticity by targeting RhoA. |journal=Mol Cell Biol |volume=28 |issue=22 |pages=6773-84 |year=2008 |pmid=18794355}}</ref>
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<ref name="pmid18450484">{{cite journal |author=Teng G, Hakimpour P, Landgraf P, Rice A, Tuschl T, Casellas R, Papavasiliou FN |title=MicroRNA-155 is a negative regulator of activation-induced cytidine deaminase. |journal=Immunity |volume=28 |issue=5 |pages=621-9 |year=2008 |pmid=18450484}}</ref>
<ref name="pmid18367535">{{cite journal |author=Yin Q, McBride J, Fewell C, Lacey M, Wang X, Lin Z, Cameron J, Flemington EK |title=MicroRNA-155 is an Epstein-Barr virus-induced gene that modulates Epstein-Barr virus-regulated gene expression pathways. |journal=J Virol |volume=82 |issue=11 |pages=5295-306 |year=2008 |pmid=18367535}}</ref>
<ref name="pmid18354490">{{cite journal |author=Zhang T, Nie K, Tam W |title=BIC is processed efficiently to microRNA-155 in Burkitt lymphoma cells. |journal=Leukemia |volume=22 |issue=9 |pages=1795-7 |year=2008 |pmid=18354490}}</ref>
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<ref name="pmid18299402">{{cite journal |author=O'Connell RM, Rao DS, Chaudhuri AA, Boldin MP, Taganov KD, Nicoll J, Paquette RL, Baltimore D |title=Sustained expression of microRNA-155 in hematopoietic stem cells causes a myeloproliferative disorder. |journal=J Exp Med |volume=205 |issue=3 |pages=585-94 |year=2008 |pmid=18299402}}</ref>
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</div>
{{reflist|2}}


==External links==
==External links==


[http://www.mirbase.org/cgi-bin/mirna_entry.pl?acc=MI0000681 miRBase entry for mir-155]
[http://www.mirbase.org/cgi-bin/mirna_entry.pl?acc=MI0000681 miRBase entry for mir-155]
* {{Rfam|id=RF00731|name=mir-155 microRNA precursor family}}


[[Category:MicroRNA]]
[[Category:MicroRNA]]

Revision as of 12:49, 2 November 2010

mir-155
Identifiers
Symbolmir-155
RfamRF00731
miRBase familyMIPF0000157
Other data
RNA typemicroRNA
Domain(s)Eukaryota;
PDB structuresPDBe


In molecular biology, mir-155 microRNA is a short RNA molecule. MicroRNAs function to regulate the expression levels of other genes by a several mechanisms.


See also

Further reading

  1. ^ Huang RS, Hu GQ, Lin B, Lin ZY, Sun CC (2010). "MicroRNA-155 Silencing Enhances Inflammatory Response and Lipid Uptake in Oxidized Low-Density Lipoprotein-Stimulated Human THP-1 Macrophages". J Investig Med. PMID 21030878.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  2. ^ Ceolotto G, Papparella I, Bortoluzzi A, Strapazzon G, Ragazzo F, Bratti P, Fabricio AS, Squarcina E, Gion M, Palatini P, Semplicini A (2010). "Interplay Between miR-155, AT1R A1166C Polymorphism, and AT1R Expression in Young Untreated Hypertensives". Am J Hypertens. PMID 20966899.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  3. ^ Wang G, Tam LS, Li EK, Kwan BC, Chow KM, Luk CC, Li PK, Szeto CC (2010). "Serum and Urinary Cell-free MiR-146a and MiR-155 in Patients with Systemic Lupus Erythematosus". J Rheumatol. PMID 20952466.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  4. ^ Kutty RK, Nagineni CN, Samuel W, Vijayasarathy C, Hooks JJ, Redmond TM (2010). "Inflammatory cytokines regulate microRNA-155 expression in human retinal pigment epithelial cells by activating JAK/STAT pathway". Biochem Biophys Res Commun. PMID 20950585.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  5. ^ Imaizumi T, Tanaka H, Tajima A, Yokono Y, Matsumiya T, Yoshida H, Tsuruga K, Aizawa-Yashiro T, Hayakari R, Inoue I, Ito E, Satoh K (2010). "IFN-γ and TNF-α Synergistically Induce microRNA-155 Which Regulates TAB2/IP-10 Expression in Human Mesangial Cells". Am J Nephrol. 32 (5): 462–468. PMID 20948191.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  6. ^ {{cite journal |author=Thompson RC, Herscovitch M, Zhao I, Ford TJ, Gilmore TD |title=NF-{kappa}B down-regulates expression of the B-lymphoma marker CD10 through a miR-155/PU.1 pathway. |journal=J Biol Chem |volume= |issue= |pages= |year=2010 |pmid=20947507}}
  7. ^ Wang P, Hou J, Lin L, Wang C, Liu X, Li D, Ma F, Wang Z, Cao X (2010). "Inducible microRNA-155 Feedback Promotes Type I IFN Signaling in Antiviral Innate Immunity by Targeting Suppressor of Cytokine Signaling 1". J Immunol. PMID 20937844.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  8. ^ O'Connell RM, Kahn D, Gibson WS, Round JL, Scholz RL, Chaudhuri AA, Kahn ME, Rao DS, Baltimore D (2010). "MicroRNA-155 Promotes Autoimmune Inflammation by Enhancing Inflammatory T Cell Development". Immunity. 33 (4): 607–19. PMID 20888269.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  9. ^ Xia QS, Ishigaki Y, Zhao X, Shimasaki T, Nakajima H, Nakagawa H, Takegami T, Chen ZH, Motoo Y (2010). "Human SMG-1 is Involved in Gemcitabine-Induced Primary microRNA-155/BIC Up-Regulation in Human Pancreatic Cancer PANC-1 Cells". Pancreas. PMID 20871480.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  10. ^ Zhou H, Huang X, Cui H, Luo X, Tang Y, Chen S, Wu L, Shen N (2010). "miR-155 and its star-form partner miR-155* cooperatively regulate type I interferon production by human plasmacytoid dendritic cells". Blood. PMID 20852130.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  11. ^ Linnstaedt SD, Gottwein E, Skalsky RL, Luftig MA, Cullen BR (2010). "Virally Induced Cellular MicroRNA miR-155 Plays a Key Role in B-Cell Immortalization by Epstein-Barr Virus". J Virol. 84 (22): 11670–8. PMID 20844043.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  12. ^ Zheng L, Xu CC, Chen WD, Shen WL, Ruan CC, Zhu LM, Zhu DL, Gao PJ (2010). "MicroRNA-155 regulates angiotensin II type 1 receptor expression and phenotypic differentiation in vascular adventitial fibroblasts". Biochem Biophys Res Commun. 400 (4): 483–8. PMID 20735984.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  13. ^ Sonkoly E, Janson P, Majuri ML, Savinko T, Fyhrquist N, Eidsmo L, Xu N, Meisgen F, Wei T, Bradley M, Stenvang J, Kauppinen S, Alenius H, Lauerma A, Homey B, Winqvist O, StÃ¥hle M, Pivarcsi A (2010). "MiR-155 is overexpressed in patients with atopic dermatitis and modulates T-cell proliferative responses by targeting cytotoxic T lymphocyte-associated antigen 4". J Allergy Clin Immunol. 126 (3): 581-9.e1-20. PMID 20673989.{{cite journal}}: CS1 maint: multiple names: authors list (link)
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  15. ^ Boesch-Saadatmandi C, Loboda A, Wagner AE, Stachurska A, Jozkowicz A, Dulak J, Döring F, Wolffram S, Rimbach G (2010). "Effect of quercetin and its metabolites isorhamnetin and quercetin-3-glucuronide on inflammatory gene expression: role of miR-155". J Nutr Biochem. PMID 20579867.{{cite journal}}: CS1 maint: multiple names: authors list (link)
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  19. ^ Hu YL, Fong S, Largman C, Shen WF (2010). "HOXA9 regulates miR-155 in hematopoietic cells". Nucleic Acids Res. 38 (16): 5472–8. PMID 20444872.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  20. ^ McCoy CE, Sheedy FJ, Qualls JE, Doyle SL, Quinn SR, Murray PJ, O'Neill LA (2010). "IL-10 inhibits miR-155 induction by toll-like receptors". J Biol Chem. 285 (27): 20492–8. PMID 20435894.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  21. ^ Yin Q, Wang X, Fewell C, Cameron J, Zhu H, Baddoo M, Lin Z, Flemington EK (2010). "MicroRNA miR-155 inhibits bone morphogenetic protein (BMP) signaling and BMP-mediated Epstein-Barr virus reactivation". J Virol. 84 (13): 6318–27. PMID 20427544.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  22. ^ Zhu J, Hu XQ, Guo GL, Zhang Y, Wang OC, You J, Huang QD, Zhang XH (2010). "[Expression and its clinical significance of miR-155 in human primary breast cancer.]". Zhonghua Wai Ke Za Zhi. 48 (3): 205–8. PMID 20388420.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  23. ^ Kong W, He L, Coppola M, Guo J, Esposito NN, Coppola D, Cheng JQ (2010). "MicroRNA-155 regulates cell survival, growth, and chemosensitivity by targeting FOXO3a in breast cancer". J Biol Chem. 285 (23): 17869–79. PMID 20371610.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  24. ^ Xia QS, Ishigaki Y, Sun L, Chen R, Motoo Y (2010). "[Effect of anti-cancer drugs on the expression of BIC/miR-155 in human pancreatic cancer PANC-1 cells]". Zhonghua Yi Xue Za Zhi. 90 (2): 123–7. PMID 20356498.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  25. ^ Jiang S, Zhang HW, Lu MH, He XH, Li Y, Gu H, Liu MF, Wang ED (2010). "MicroRNA-155 functions as an OncomiR in breast cancer by targeting the suppressor of cytokine signaling 1 gene". Cancer Res. 70 (8): 3119–27. PMID 20354188.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  26. ^ Valeri N, Gasparini P, Fabbri M, Braconi C, Veronese A, Lovat F, Adair B, Vannini I, Fanini F, Bottoni A, Costinean S, Sandhu SK, Nuovo GJ, Alder H, Gafa R, Calore F, Ferracin M, Lanza G, Volinia S, Negrini M, McIlhatton MA, Amadori D, Fishel R, Croce CM (2010). "Modulation of mismatch repair and genomic stability by miR-155". Proc Natl Acad Sci U S A. 107 (15): 6982–7. PMID 20351277.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  27. ^ Ryu JK, Hong SM, Karikari CA, Hruban RH, Goggins MG, Maitra A (2010). "Aberrant MicroRNA-155 expression is an early event in the multistep progression of pancreatic adenocarcinoma". Pancreatology. 10 (1): 66–73. PMID 20332664.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  28. ^ Fabani MM, Abreu-Goodger C, Williams D, Lyons PA, Torres AG, Smith KG, Enright AJ, Gait MJ, Vigorito E (2010). "Efficient inhibition of miR-155 function in vivo by peptide nucleic acids". Nucleic Acids Res. 38 (13): 4466–75. PMID 20223773.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  29. ^ Tang B, Xiao B, Liu Z, Li N, Zhu ED, Li BS, Xie QH, Zhuang Y, Zou QM, Mao XH (2010). "Identification of MyD88 as a novel target of miR-155, involved in negative regulation of Helicobacter pylori-induced inflammation". FEBS Lett. 584 (8): 1481–6. PMID 20219467.{{cite journal}}: CS1 maint: multiple names: authors list (link)
  30. ^ Fassi Fehri L, Koch M, Belogolova E, Khalil H, Bolz C, Kalali B, Mollenkopf HJ, Beigier-Bompadre M, Karlas A, Schneider T, Churin Y, Gerhard M, Meyer TF (2010). "Helicobacter pylori induces miR-155 in T cells in a cAMP-Foxp3-dependent manner". PLoS One. 5 (3): e9500. PMID 20209161.{{cite journal}}: CS1 maint: multiple names: authors list (link)
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External links

miRBase entry for mir-155