FMR1-AS1 gene: Difference between revisions
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←Created page with '{{PBB|geneid=100126270}} In molecular biology, '''FMR1 antisense RNA 1''' ('''FMR1-AS1'''), also known as ASFMR1 or FMR4, is a long non-coding RNA. The FMR1-AS1...' |
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Revision as of 10:17, 1 September 2011
Template:PBB In molecular biology, FMR1 antisense RNA 1 (FMR1-AS1), also known as ASFMR1 or FMR4, is a long non-coding RNA. The FMR1-AS1 gene overlaps, and is antisense to, the CGG repeat region of the FMR1 gene.[1] Its expression is upregulated in fragile X syndrome premutation carriers, and silenced in patients with fragile X syndrome.[1][2] FMR1-AS1 has an anti-apoptotic function.[2]
See also
References
- ^ a b Ladd PD, Smith LE, Rabaia NA, Moore JM, Georges SA, Hansen RS; et al. (2007). "An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals". Hum Mol Genet. 16 (24): 3174–87. doi:10.1093/hmg/ddm293. PMID 17921506.
{{cite journal}}: Explicit use of et al. in:|author=(help)CS1 maint: multiple names: authors list (link) - ^ a b Khalil AM, Faghihi MA, Modarresi F, Brothers SP, Wahlestedt C (2008). "A novel RNA transcript with antiapoptotic function is silenced in fragile X syndrome". PLoS One. 3 (1): e1486. doi:10.1371/journal.pone.0001486. PMC 2194623. PMID 18213394.
{{cite journal}}: CS1 maint: PMC format (link) CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)