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== Localization ==
== Localization ==
* [[Lung]]<ref>{{Cite pmid|22187684}}</ref>
* [[Lung]]<ref>{{Cite pmid|22187684}}</ref> or Bronchus<ref>{{Cite pmid|17982543}}</ref>
* [[Liver]]<ref>{{Cite pmid|20931439}}</ref>
* [[Liver]]<ref>{{Cite pmid|20931439}}</ref>



Revision as of 15:32, 16 April 2014

Inflammatory myofibroblastic tumour

Inflammatory myofibroblastic tumour is a lesional pattern of inflammatory pseudotumour, as plasma cell granuloma[1]. It is abbreviated IMT.

Symptoms

The symptoms depend on the specific location of the tumour, which can be anywhere in the body.[2]

Diagnosis

Inflammatory myofibroblastic tumours are diagnosed based on their appearance under the microscope, by pathologists.[3] Medical imaging findings are non-specific.

Pathology

Inflammatory myofibroblastic tumours are characterized by a mix of inflammatory cells, e.g. plasma cells, lymphocytes and eosinophils, and bland spindle cells without nuclear atypia. These tumours may have necrosis, hemorrhage, focal calcification and mitotic activity.

The histologic differential diagnosis includes:

Approximately half of IMTs have a rearrangement of the ALK gene.[4]

Localization

See also

References

  1. ^ Manohar, B.; Bhuvaneshwari, S. (Jan 2011). "Plasma cell granuloma of gingiva". J Indian Soc Periodontol. 15 (1): 64–6. doi:10.4103/0972-124X.82275. PMID 21772725.{{cite journal}}: CS1 maint: unflagged free DOI (link)
  2. ^ Singhal, M.; Ramanathan, S.; Das, A.; Singh, G.; Bagga, R.; Khandelwal, N. (2011). "Omental inflammatory myofibroblastic tumour mimicking peritoneal carcinomatosis". Cancer Imaging. 11: 19–22. doi:10.1102/1470-7330.2011.0005. PMID 21435987. {{cite journal}}: Cite has empty unknown parameter: |month= (help)
  3. ^ Soga, H.; Yao, A.; Matsushita, K.; Shimogaki, H.; Kawabata, G. "Inflammatory pseudotumor of the retroperitoneum removed via a retroperitoneoscopic approach". JSLS. 15 (2): 272–4. doi:10.4293/108680811X13071180406871. PMID 21902993. {{cite journal}}: Cite has empty unknown parameter: |month= (help)
  4. ^ Gleason, BC.; Hornick, JL. (Apr 2008). "Inflammatory myofibroblastic tumours: where are we now?". J Clin Pathol. 61 (4): 428–37. doi:10.1136/jcp.2007.049387. PMID 17938159.
  5. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 22187684, please use {{cite journal}} with |pmid=22187684 instead.
  6. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 17982543, please use {{cite journal}} with |pmid=17982543 instead.
  7. ^ Attention: This template ({{cite pmid}}) is deprecated. To cite the publication identified by PMID 20931439, please use {{cite journal}} with |pmid=20931439 instead.