Nodular fasciitis
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| Nodular fasciitis | |
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| Classification and external resources | |
 Micrograph of nodular fasciitis showing the haphazard arrangement of cells (tissue culture-like pattern). H&E stain. |
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| ICD-10 | M72.4 |
| ICD-9 | 728.79 |
Nodular fasciitis, also known as nodular pseudosarcomatous fasciits,[1] pseudosarcomatous fasciitis,[2] and subcutaneous pseudosarcomatous fibromatosis,[1]:992 is a benign[3] soft tissue lesion most commonly found in the superficial fascia. It is most common in young persons on the upper extremities and trunk, and typically associated with previous injury at the site. It may be mistaken for a sarcoma.
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[edit] Etiology and clinical course
Similar to a dermatofibroma, it is believed to be a reparative process secondary to trauma, which is frequently not remembered. It evolves rapidly, but is usually less than 3 cm in diameter. There is an extremely low incidence of recurrence after resection.
[edit] Histology
- Histologically vast array of patterns.
- Short S-shaped fascicles, inflammation, accelerated mitotic index with normal mitoses.
- Essentially spindle cell proliferation.
- Stroma is rich in collagen and/or myxoid ground substance.
[edit] Additional images
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Low mag.
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Intermed. mag.
[edit] See also
[edit] References
- ^ a b Freedberg, et al. (2003). Fitzpatrick's Dermatology in General Medicine. (6th ed.). McGraw-Hill. ISBN 0071380760.
- ^ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
- ^ Sailon AM, Cappuccino G, Hameed M, Fleegler EJ (2008). "Nodular fasciitis of the hand over the metacarpophalangeal joint: a case report". Eplasty 8: e38. PMC 2491338. PMID 18725954. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=2491338.
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