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== Selected publications ==
== Selected publications ==
*{{cite journal|author=Hallett P, Cooper O, Sadi D, Robertson H, Mendez I, Isacson O. |title=Long-term health of dopaminergic neuron transplants in Parkinson's disease patients|journal=Cell Reports|date=26 June 2014|volume=7|issue=6|pages=1755–1761|doi=10.1016/j.celrep.2014.05.027|pmid=24910427}}
*{{cite journal|author=Hallett P, Cooper O, Sadi D, Robertson H, Mendez I, and Isacson O|title=Long-term Health of Dopaminergic Neuron Transplants in Parkinson's Disease Patients|journal=Cell Reports|date=2014|url=http://dx.doi.org/10.1016/j.celrep.2014.05.027}}
*{{cite journal|author=Hallett P, Cooper O, Sadi D, Robertson H, Mendez I, and Isacson O|title=Long-term Health of Dopaminergic Neuron Transplants in Parkinson's Disease Patients|journal=Cell Reports|date=2014|url=http://dx.doi.org/10.1016/j.celrep.2014.05.027}}
*{{cite journal|author=Mendez I, Jong M, Keays-­White D, Turner G |title=The Use of Remote Presence for Health Care Delivery in a Northern Inuit Community: A Feasibility Study|journal=International Journal of Circumpolar Health|date=2013|volume=72|url=http://www.circumpolarhealthjournal.net/index.php/ijch/article/view/21112/html}}
*{{cite journal|author=Mendez I, Jong M, Keays-­White D, Turner G |title=The Use of Remote Presence for Health Care Delivery in a Northern Inuit Community: A Feasibility Study|journal=International Journal of Circumpolar Health|date=2013|volume=72|url=http://www.circumpolarhealthjournal.net/index.php/ijch/article/view/21112/html}}

Revision as of 20:33, 15 August 2014

Ivar Mendez
Alma materUniversity of Western Ontario, University of Toronto
Scientific career
Fieldsneurosurgery, sculpture, photography, philanthropy
InstitutionsUniversity of Saskatchewan, Saskatoon Health Region, Dalhousie University, Queen Elizabeth II Health Sciences Centre, Brain Repair Centre,Dalhousie University Neurosurgery

Ivar Mendez, M.D., PhD, is a Fred H. Wigmore Professor and Chairman of Surgery at the University of Saskatchewan and the Unified Head of Surgery for the Province of Saskatchewan. He is known for his pioneering work in cell transplantation for Parkinson’s disease and the use of robots in neurosurgery.

He also holds an appointment at the Department of Psychology and Neuroscience at Dalhousie University and he is the founder of the Brain Repair Centre.[1] He is also the president and founder of the Ivar Mendez International Foundation[2] that is dedicated to providing health and educational assistance to children in the Bolivian Andes. Mendez is a photographer and sculptor[3] and has published 4 books of photography.

Biography

Mendez was born in La Paz, Bolivia and immigrated with his family to Canada as a teenager. He obtained a BSc degree from the University of Toronto and then an M.D. from the University of Western Ontario (UWO). He did a neurosurgical residency training in London, and was certified in Neurosurgery from the Royal College of Physician and Surgeons of Canada in 1994 and from the American Board of Neurological Surgery in 1996. He became a fellow of the American College of Surgeons in 1998. His interest in regenerative medicine led him to obtain a PhD in Anatomy an Neurobiology from the UWO his PhD thesis was on “Neurotransmitter Interactions in Nigral Grafts”.[4] He did a postdoctoral fellowship at the University of Lund in Sweden under the supervision of Anders Bjorklund, considered the “father” of cell transplantation in Parkinson’s disease. In 2014, Saint Mary's University (Halifax) in Nova Scotia awarded Mendez a Doctor of Science (honoris causa) degree for his contribution to Neuroscience.

Scientific contributions

He pioneered the technique of multiple grafts to restore dopamine input to the parkinsonian mammalian brain.[5][6] This technique was translated into clinical trials in patients with Parkinson’s disease and showed long term survival of those grafts.[7][8][9][10] He also pioneered the use of Glial Derived Neurotrophic Factor (GDNF) in combination with fetal cells in humans.[11][12] [13][14][15] Mendez invented a transplantation delivery system to inject cells into the human brain.[16][17][18] With his team, he performed the first long-distance brain surgery robotic telementoring in the world by using a robotic arm to mentor neurosurgeons located 400 km away.[19] He is also pioneering the use of remote presence devices to deliver health care in remote locations.[20][21][22]

Inventions

  • Neural transplantation delivery system: Canadian Patent #2,281,007,[23] US Patent #7,137,969[24]

Humanitarian contributions

Mendez has established a Canadian charitable organization the Ivar Mendez International Foundation[25] to provide nutrition, dental care and art program to children in remote locations of the Bolivian Andes.[26]

Awards

  • Queen Elizabeth II Diamond Jubilee Medal[27]
  • Humanitarian of the Year Award, Canadian Red Cross - Atlantic Region[28]
  • Ten most influential Hispanics in Canada[29]
  • Dr. John Savage Memorial Award[30]

Artistic endeavors

He has published 4 books of photography [31] and has had several exhibitions of his photography and sculpture [32]

Published books

Selected publications

References

  1. ^ ["Brain Repair Centre".
  2. ^ "Ivar Mendez International Foundation".
  3. ^ "Sculpting neurosurgeon breaks the mould".
  4. ^ Mendez I, Elisevich K, Flumerfelt B (1991). "Dopaminergic innervation of substance P-containing striatal neurons by fetal nigral grafts: an ultrastructural double-labeling immunocytochemical study". The Journal of Comparative Neurology. 308 (1): 66–78. doi:10.1002/cne.903080107. PMID 1714923. {{cite journal}}: Unknown parameter |month= ignored (help)CS1 maint: multiple names: authors list (link).
  5. ^ "Mendez I, Sadi D and Hong M. Reconstruction of the nigrostriatal pathway by simultaneous intrastriatal and intranigral dopaminergic transplants. Journal of Neuroscience 1996; 16(22): 7216-7227". {{cite web}}: Check |url= value (help)
  6. ^ "Mendez I and Hong M. Reconstruction of the striato-nigro-striatal circuitry by simultaneous double dopaminergic grafts: a tracer study using fluorogold and horse radish peroxidase. Brain Research 1997; 778: 194-205". {{cite web}}: Check |url= value (help)
  7. ^ "Mendez I, Dagher A, Hong M, Gaudet P, Weerasinghe S, McAlister V, King D, Desrosiers J, Darvesh S, Acorn T and Robertson H. Simultaneous intrastriatal and intranigral fetal dopaminergic grafts in patients with Parkinson's disease. Journal of Neurosurgery 2002; 96: 589‐596". {{cite web}}: Check |url= value (help)
  8. ^ "Mendez I, Sanchez-Pernaute R, Vineula A, Ferrari D, Bjorklund L, Dagher A and Isacson O. Cell type analysis of fetal dopamine cell suspension transplants in striatum and substantia nigra of patients with Parkinson's disease. Brain 2005; 128: 1498-­‐1510". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 250 (help)
  9. ^ "Mendez I, Vinuela A, Astradsson A, Mukhida K, Hallet P, Robertson H, Tierney T, Holness R, Dagher A, Trojanowski JQ, Isacson I. Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years. Nature Medicine 2008; 14: 507-509". {{cite web}}: Check |url= value (help)
  10. ^ "Hallett P, Cooper O, Sadi D, Robertson H, Mendez I, and Isacson O. Long-­‐term Health of Dopaminergic Neuron Transplants in Parkinson's Disease Patients. Cell Reports (2014)". {{cite web}}: soft hyphen character in |title= at position 73 (help)
  11. ^ "Apostolides C, Sanford E, Hong M and Mendez I. Glial cell line-­‐derived neurotrophic factor improves intrastriatal graft survival of stored dopaminergic cells. Neuroscience 1998; 83(2): 363-­372". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 65 (help)
  12. ^ "Mehta V, Hong M, Spears J and Mendez, I. Enhancement of graft survival and sensorimotor behavioral recovery in rats undergoing transplantation with dopaminergic cells exposed to glial cell line-­derived neurotrophic factor. Journal of Neurosurgery 1998; 88: 1088-1095". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 196 (help)
  13. ^ "Mendez I, Dagher A, Hong M, Hebb A, Gaudet P, Law A, Weerasinghe S, King D, Desrosiers J, Darvesh S, Acorn T, and Robertson H. Exposure of human fetal nigral tissue to glial cell line-­derived neurotrophic factor enhances survival in two patients with Parkinson's disease. Journal of Neurosurgery 2000; 92: 863-869". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 186 (help)
  14. ^ "Mendez I, Sanchez-­Pernaute R, Vineula A, Ferrari D, Bjorklund L, Dagher A and Isacson O. Cell type analysis of fetal dopamine cell suspension transplants in striatum and substantia nigra of patients with Parkinson's disease. Brain 2005; 128: 1498-­1510". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 19 (help)
  15. ^ "Mendez I, Vinuela A, Astradsson A, Mukhida K, Hallet P, Robertson H, Tierney T, Holness R, Dagher A, Trojanowski JQ, Isacson I. Dopamine neurons implanted into people with Parkinson's disease survive without pathology for 14 years. Nature Medicine 2008; 14: 507-­509". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 263 (help)
  16. ^ "Mendez I, Hong M, Smith S, Dagher A, and Desrosiers J. A neural transplantation cannula and microinjector system: experimental and clinical experience. Neurosurgical Focus 1999; 7(3): Article #2". {{cite web}}: Check |url= value (help)
  17. ^ "Mendez I, Dagher A, Hong M, Hebb A, Gaudet P, Law A, Weerasinghe S, King D, Desrosiers J, Darvesh S, Acorn T, and Robertson H. Exposure of human fetal nigral tissue to glial cell line-­derived neurotrophic factor enhances survival in two patients with Parkinson's disease. Journal of Neurosurgery 2000; 92: 863-­869". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 186 (help)
  18. ^ "Mendez I, Dagher A, Hong M, Gaudet P, Weerasinghe S, McAlister V, King D, Desrosiers J, Darvesh S, Acorn T and Robertson H. Simultaneous intrastriatal and intranigral fetal dopaminergic grafts in patients with Parkinson's disease. Journal of Neurosurgery 2002; 96: 589-­596". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 272 (help)
  19. ^ "Mendez I, Hill R, Clarke DB, Kolyvas G and Walling S. Robotic long-­distance telementoring in neurosurgery. Neurosurgery 2005; 56(3): 434-440". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 69 (help)
  20. ^ "Mendez I, Song M, Chiasson P and Bustamante L. Point-­of-­care Programming for Neuromodulation: A Feasibility Study Using Remote Presence. Neurosurgery. 2013; 72: 99-­108". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 54 (help)
  21. ^ "Mendez I, Van den Hof M. Mobile remote-­presence devices for point-­of-­care health care delivery. Canadian Medical Association Journal. 2013; 120223". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 40 (help)
  22. ^ "Mendez I, Jong M, Keays-­White D, Turner G. The Use of Remote Presence for Health Care Delivery in a Northern Inuit Community: A Feasibility Study. International Journal of Circumpolar Health. 2013; 72:21112". {{cite web}}: Check |url= value (help); soft hyphen character in |title= at position 25 (help)
  23. ^ "Canadian patent #2,282,007".
  24. ^ "US patent #7,137,969".
  25. ^ "Ivar Mendez International Foundation".
  26. ^ "Canadian Red Cross 2010 Humanitarian of the Year Award".
  27. ^ "Queen Elizabeth II Diamond Jubilee Medal".
  28. ^ "Dr. Ivar Mendez honoured for humanitarian work".
  29. ^ "Hispanic Business: 10 most influential Hispanic Canadians – 2009" (PDF).
  30. ^ "Dr. John Savage Award Presented to Dr. Ivar Mendez".
  31. ^ "Publications".
  32. ^ "Solo Exhibitions".

External links

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