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==Background==
==Background==


Budapest Reference Connectome is a combination of the brain graphs of 96 subjects. Only those edges are selected which are present in a given percentage of the graphs. Each of the selected edges has a certain weight in each of the graphs containing that edge, so these multiple weights are combined into a single weight, by taking either their mean or median. The user interface allows customization of these parameters. There is an option for viewing the female or male reference connectome.
Budapest Reference Connectome is a combination of the brain graphs of 96 subjects. Only those edges are selected which are present in a given percentage of the graphs. Each of the selected edges has a certain weight in each of the graphs containing that edge, so these multiple weights are combined into a single weight, by taking either their mean or median. The user interface allows customization of these parameters. There is an option for viewing and comparing the female or male reference connectome. The connectomes of women contain significantly more edges than those of men, and a larger portion of the edges in the connectomes of women run between the two hemispheres <ref name="IngalhalikarSmith2013">{{cite journal|last1=Ingalhalikar|first1=M.|last2=Smith|first2=A.|last3=Parker|first3=D.|last4=Satterthwaite|first4=T. D.|last5=Elliott|first5=M. A.|last6=Ruparel|first6=K.|last7=Hakonarson|first7=H.|last8=Gur|first8=R. E.|last9=Gur|first9=R. C.|last10=Verma|first10=R.|title=Sex differences in the structural connectome of the human brain|journal=Proceedings of the National Academy of Sciences|volume=111|issue=2|year=2013|pages=823–828|issn=0027-8424|doi=10.1073/pnas.1316909110}}</ref> <ref name="Szalkai2015">{{cite journal|last1=Szalkai|first1=Balázs|last2=Varga|first2=Bálint|last3=Grolmusz|first3=Vince|title=Graph Theoretical Analysis Reveals: Women’s Brains Are Better Connected than Men’s|journal=PLOS ONE|volume=10|issue=7|year=2015|pages=e0130045|issn=1932-6203|doi=10.1371/journal.pone.0130045}}</ref>.


== References ==
== References ==

Revision as of 12:00, 7 July 2015

Budapest Reference Connectome
Developer(s)Balázs Szalkai, Csaba Kerepesi, Bálint Varga, Vince Grolmusz
Stable release
2.0
Written inPerl, Javascript, WebGL
Available inEnglish
TypeConnectomics
Websitehttp://pitgroup.org/connectome/

The Budapest Reference Connectome is a depiction of the anatomical connections, or connectome, of 96 healthy people collectively.[1] It has been computed from diffusion MRI datasets of the Human Connectome Project into a reference connectome (or brain graph), which can be downloaded and visualized in 3D.

Features

The Budapest Reference Connectome has 1015 nodes, but those corresponding to the same larger cerebral area are drawn at the same spot, for a cleaner view. You can use your mouse to zoom and rotate, and and if you click a node you can see only the connections of that node.

Background

Budapest Reference Connectome is a combination of the brain graphs of 96 subjects. Only those edges are selected which are present in a given percentage of the graphs. Each of the selected edges has a certain weight in each of the graphs containing that edge, so these multiple weights are combined into a single weight, by taking either their mean or median. The user interface allows customization of these parameters. There is an option for viewing and comparing the female or male reference connectome. The connectomes of women contain significantly more edges than those of men, and a larger portion of the edges in the connectomes of women run between the two hemispheres [2] [3].

References

  1. ^ Szalkai, Balázs; et al. (2015). "The Budapest Reference Connectome Server v2.0". Neuroscience Letters. doi:10.1016/j.neulet.2015.03.071. PMID 25862487. {{cite journal}}: Explicit use of et al. in: |author2= (help)
  2. ^ Ingalhalikar, M.; Smith, A.; Parker, D.; Satterthwaite, T. D.; Elliott, M. A.; Ruparel, K.; Hakonarson, H.; Gur, R. E.; Gur, R. C.; Verma, R. (2013). "Sex differences in the structural connectome of the human brain". Proceedings of the National Academy of Sciences. 111 (2): 823–828. doi:10.1073/pnas.1316909110. ISSN 0027-8424.
  3. ^ Szalkai, Balázs; Varga, Bálint; Grolmusz, Vince (2015). "Graph Theoretical Analysis Reveals: Women's Brains Are Better Connected than Men's". PLOS ONE. 10 (7): e0130045. doi:10.1371/journal.pone.0130045. ISSN 1932-6203.{{cite journal}}: CS1 maint: unflagged free DOI (link)