CDY1: Difference between revisions

CDY1
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2FBM
Identifiers
Aliases	CDY1, CDY, CDY1A, chromodomain protein, Y-linked, 1, chromodomain Y-linked 1
External IDs	OMIM: 400016; HomoloGene: 36165; GeneCards: CDY1; OMA:CDY1 - orthologs
Gene location (Human)
Chr.	Y chromosome (human)
End	25,624,902 bp
RNA expression pattern
	Top expressed in
	testicle; ; multicellular organism;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	histone acetyltransferase activity; methylated histone binding; transferase activity; acyltransferase activity; catalytic activity; transcription corepressor activity;
Cellular component	nucleus;
Biological process	histone acetylation; metabolism; spermatogenesis; negative regulation of nucleic acid-templated transcription;
	Sources:Amigo / QuickGO
Orthologs
	9085
	n/a
	ENSG00000172288
	n/a
	Q9Y6F8
	n/a
	NM_004680; NM_170723
	n/a
	NP_004671; NP_733841
	n/a
	Wikidata
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Revision as of 05:25, 25 January 2017

Testis-specific chromodomain protein Y 1 is a protein that in humans is encoded by the CDY1 gene.^[3]^[4]

Template:PBB Summary The gene is thought to be related to high-altitude adaptation in humans.^[5]

References

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000172288 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Lahn BT, Page DC (Nov 1997). "Functional coherence of the human Y chromosome". Science. 278 (5338): 675–80. doi:10.1126/science.278.5338.675. PMID 9381176.
^ "Entrez Gene: CDY1 chromodomain protein, Y-linked, 1".
^ Zhang YB, Li X, Zhang F, Wang DM, Yu J; Li; Zhang; Wang; Yu (2012). "A preliminary study of copy number variation in Tibetans". PLoS ONE. 7 (7): e41768. Bibcode:2012PLoSO...741768Z. doi:10.1371/journal.pone.0041768. PMC 3402393. PMID 22844521.{{cite journal}}: CS1 maint: multiple names: authors list (link) CS1 maint: unflagged free DOI (link)

@@ Line 1: / Line 1: @@
-{{Multiple issues|
-{{Underlinked|date=May 2016}}
-{{Orphan|date=February 2009}}
-}}
 {{Infobox_gene}}
 '''Testis-specific chromodomain protein Y 1''' is a [[protein]] that in humans is encoded by the ''CDY1'' [[gene]].<ref name="pmid9381176">{{cite journal | vauthors = Lahn BT, Page DC | title = Functional coherence of the human Y chromosome | journal = Science | volume = 278 | issue = 5338 | pages = 675–80 |date=Nov 1997 | pmid = 9381176 | pmc =  | doi =10.1126/science.278.5338.675  }}</ref><ref name="entrez">{{cite web | title = Entrez Gene: CDY1 chromodomain protein, Y-linked, 1| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=9085| accessdate = }}</ref>
@@ Line 10: / Line 5: @@
 {{PBB_Summary
 | section_title =
-| summary_text = This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.<ref name="entrez"/>
+| summary_text = This gene encodes a protein containing a [[chromodomain]] and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more telomeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.<ref name="entrez"/>
+}} The gene is thought to be related to [[high-altitude adaptation in humans]].<ref>{{cite journal |author=Zhang YB, Li X, Zhang F, Wang DM, Yu J|year=2012 |title=A preliminary study of copy number variation in Tibetans | url=http://dx.plos.org/10.1371/journal.pone.0041768 |journal=PLoS ONE |volume=7|issue=7|pages=e41768|pmid=22844521| pmc=3402393 |doi=10.1371/journal.pone.0041768|last2=Li |last3=Zhang |last4=Wang |last5=Yu |bibcode=2012PLoSO...741768Z }}</ref>
-}}
 ==References==

Revision as of 05:25, 25 January 2017

References

Further reading