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Fatty acid amide hydrolase 2 or FAAH2 (EC 3.5.1.99 , oleamide hydrolase 2, anandamide amidohydrolase 2) is a member of the serine hydrolase family of enzymes .[3]
Fatty acid amide hydrolase 2 degrades endocannabinoids and defects in this enzyme have been associated with neurologic and psychiatric disorders.[4]
References
^ a b c GRCh38: Ensembl release 89: ENSG00000165591 – Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Wei BQ, Mikkelsen TS, McKinney MK, Lander ES, Cravatt BF (December 2006). "A second fatty acid amide hydrolase with variable distribution among placental mammals". The Journal of Biological Chemistry . 281 (48): 36569–78. doi :10.1074/jbc.M606646200 . PMID 17015445 . {{cite journal }}
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^ Sirrs S, van Karnebeek CD, Peng X, Shyr C, Tarailo-Graovac M, Mandal R, et al. (March 2015). "Defects in fatty acid amide hydrolase 2 in a male with neurologic and psychiatric symptoms" . Orphanet Journal of Rare Diseases . 10 : 38. doi :10.1186/s13023-015-0248-3 . PMC 4423390 . PMID 25885783 . {{cite journal }}
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