David Argyle: Difference between revisions
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In 2008, Professor Argyle was awarded the Petplan Prize for Scientific Achievement and in 2014, the Kennel Club International Award for contributions to canine health<ref>{{Cite web|title=Head of School wins prestigious veterinary award|url=https://www.ed.ac.uk/vet/news-events/archive/2015news/award|access-date=2020-10-26|website=The University of Edinburgh|language=en}}</ref>. |
In 2008, Professor Argyle was awarded the Petplan Prize for Scientific Achievement and in 2014, the Kennel Club International Award for contributions to canine health<ref>{{Cite web|title=Head of School wins prestigious veterinary award|url=https://www.ed.ac.uk/vet/news-events/archive/2015news/award|access-date=2020-10-26|website=The University of Edinburgh|language=en}}</ref>. |
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== Personal Life == |
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David Argyle was born in Birmingham on the 18th of January 1968 to parents William Argyle and Hilda May (nee Fern). He was the youngest of four children. He met his wife Sally at the University of Glasgow in 1992 and they were married in 1993. They have two children. |
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==Veterinary Career== |
==Veterinary Career== |
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In 2019 the Sunday Times published two articles alleging a 'toxic' culture at the Dick Vet school in Edinburgh, of which Argyle is Head. In 2020, an independent review (Intersol Global Report) was commissioned by the University of Edinburgh. The summary of the Intersol report was leaked to the national and veterinary press (Sunday Times<ref>https://www.thetimes.co.uk/article/top-vet-professor-david-argyle-at-centre-of-bullying-claims-at-edinburgh-university-5hlnmwjl8</ref> and The Veterinary Record <ref>http://dx.doi.org/10.1136/vr.m3998</ref> <ref>http://dx.doi.org/10.1136/vr.m3991</ref>), leading the RCVS to warn against 'Trial by media'. The allegations were rejected by an independent investigation, which concluded there was no evidence of misconduct. This conclusion was upheld after an appeal.<ref>{{Cite web|last=Frost|first=Sara|date=2020-10-23GMT06:00:07+00:00|title=No trial by media for next college president – RCVS|url=https://www.vettimes.co.uk/news/no-trial-by-media-for-next-college-president-rcvs/|access-date=2020-10-26|website=Vet Times}}</ref> |
In 2019 the Sunday Times published two articles alleging a 'toxic' culture at the Dick Vet school in Edinburgh, of which Argyle is Head. In 2020, an independent review (Intersol Global Report) was commissioned by the University of Edinburgh. The summary of the Intersol report was leaked to the national and veterinary press (Sunday Times<ref>https://www.thetimes.co.uk/article/top-vet-professor-david-argyle-at-centre-of-bullying-claims-at-edinburgh-university-5hlnmwjl8</ref> and The Veterinary Record <ref>http://dx.doi.org/10.1136/vr.m3998</ref> <ref>http://dx.doi.org/10.1136/vr.m3991</ref>), leading the RCVS to warn against 'Trial by media'. The allegations were rejected by an independent investigation, which concluded there was no evidence of misconduct. This conclusion was upheld after an appeal.<ref>{{Cite web|last=Frost|first=Sara|date=2020-10-23GMT06:00:07+00:00|title=No trial by media for next college president – RCVS|url=https://www.vettimes.co.uk/news/no-trial-by-media-for-next-college-president-rcvs/|access-date=2020-10-26|website=Vet Times}}</ref> |
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== Research == |
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Professor Argyle’s research career began in the department of Veterinary Pathology (Glasgow) as a Wellcome PhD Fellowship under Professors David Onions and Neil Gorman. He was involved in isolating canine and feline cytokine genes, developing bioassays and taking these reagents towards clinical application, specifically in the development of vaccines for retroviral diseases and gene therapy tools. |
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Rooted in comparative biology, the majority of his career has involved studying the basic biology of cancer with the aim of identifying new diagnostic and therapeutic targets. This has included studies on the role of telomerase in cancer cell maintenance to, more recently, focusing on the understanding of the role of cancer stem cells in tumour initiation and metastatic disease. |
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His research in canine and feline cancers has established large animal models for human cancer studies such as the identification of biomarkers for breast cancer radio-resistance and the development of canine bone cancer as a model for human paediatric osteosarcoma. This work laid the foundation for a multidisciplinary programme developing implantable biosensors to monitor tumour microenvironment (IMPACT Implantable Microsystems for Anti-Cancer Therapy, an EPSRC programme involving Engineering, Medicine, Chemistry, Veterinary Medicine and Social Science), which successfully developed an in vivo sheep model for implantable devices in lung cancer. |
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== Publications == |
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Professor Argyle has over 150 peer-reviewed publications. |
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=== Books and Chapters === |
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*''Decision Making in Small Animal Oncology'' (2009) |
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*''Decision Making in Small Animal Oncology'' ''(2009)''<ref>{{Cite web|title=Decision Making in Small Animal Oncology David Argyle - Google Search|url=https://www.google.com/search?kgmid=/g/12bmbmmd8&hl=en-GB&q=Decision+Making+in+Small+Animal+Oncology+David+Argyle&kgs=a1e2688b19b3197e&shndl=0&source=sh/x/kp&entrypoint=sh/x/kp|access-date=2020-10-26|website=www.google.com}}</ref> |
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*''Advances in cancer diagnostics (2008)''<ref>{{Cite journal|last=Argyle|first=D. J.|date=2008|title=Advances in cancer diagnostics|url=https://www.research.ed.ac.uk/portal/en/publications/advances-in-cancer-diagnostics(0fc0f402-f68a-4efb-bf5f-ae099d1a0cf1).html|journal=Proceedings of the 33rd World Small Animal Veterinary Association Congress|language=English|publisher=Australian Small Animal Veterinary Association}}</ref> |
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*''Decision making in feline cancer patients (2008)''<ref>{{Cite journal|last=Argyle|first=D. J.|date=2008|title=Decision making in feline cancer patients|url=https://www.research.ed.ac.uk/portal/en/publications/decision-making-in-feline-cancer-patients(f7197f57-4e2b-49b7-bfca-9ef1d9b1b093).html|journal=Advances in cancer diagnostics|language=English}}</ref> |
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*''What is new in canine and feline lymphoma (2008)''<ref>{{Cite journal|last=Argyle|first=D. J.|date=2008|title=What is new in canine and feline lymphoma|url=https://www.research.ed.ac.uk/portal/en/publications/what-is-new-in-canine-and-feline-lymphoma(c0d2219c-c401-4c1a-b87e-479b535d4cfd).html|journal=Advances in cancer diagnostics|language=English|pages=518–520}}</ref> |
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*''Preclinical Organotypic Models for the Assessment of Novel Cancer Therapeutics and Treatment (2019)''<ref>{{Cite journal|last=Ward|first=Carol|last2=Meehan|first2=James|last3=Gray|first3=Mark|last4=Kunkler|first4=Ian|last5=Langdon|first5=Simon|last6=Murray|first6=Alan|last7=Argyle|first7=David|date=2019-03-12|title=Preclinical Organotypic Models for the Assessment of Novel Cancer Therapeutics and Treatment|url=https://www.research.ed.ac.uk/portal/en/publications/preclinical-organotypic-models-for-the-assessment-of-novel-cancer-therapeutics-and-treatment(006e1e3d-8015-4e24-8537-328f53e1616a).html|journal=Current Topics in Microbiology and Immunology|language=English|doi=10.1007/82_2019_159}}</ref> |
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==References== |
==References== |
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Revision as of 15:18, 26 October 2020
Professor David Argyle BVMS PhD DECVIM-CA (Oncology) FRSE FRSA FRCVS is Head of the Royal (Dick) School of Veterinary Studies and Head of the Roslin Institute[1]. He also serves as Deputy Head of the College of Medicine and Veterinary Medicine and Junior Vice President for the Royal College of Veterinary Surgeons (RCVS)[2].
Professor Argyle specialises in comparative oncology and cancer in animals. Recognised as an RCVS Specialist in Veterinary Oncology, Professor Argyle was also awarded foundation Diplomat status in Veterinary Oncology in 2005 in recognition for his standing and contributions to the discipline.[3] He later established the Riddell Swann Cancer Centre at Easter Bush, now considered a model for comprehensive cancer therapy and a training ground for the next generation of clinical oncologists.[4] Professor Argyle is Head of the examining board for the European Diploma Qualification in Oncology[5], chair of the examination board for the ECVIM residency programme for Oncology[6], and has trained a number of clinical oncologists now in private practice or clinical roles. In 2016 he was elected Fellow of the Royal Society of Edinburgh, and in the same year Fellow of the Royal College of Veterinary Surgeons (for meritorious contributions to veterinary research).[7] As Dean of Veterinary Medicine at the University of Edinburgh, he has successfully introduced a new career pathway for veterinarians to enable both research and clinical training through the Wellcome Trust Funded “Edinburgh Clinical Academic track for Veterinarians” (ECAT-V).[8]
In 2008, Professor Argyle was awarded the Petplan Prize for Scientific Achievement and in 2014, the Kennel Club International Award for contributions to canine health[9].
Personal Life
David Argyle was born in Birmingham on the 18th of January 1968 to parents William Argyle and Hilda May (nee Fern). He was the youngest of four children. He met his wife Sally at the University of Glasgow in 1992 and they were married in 1993. They have two children.
Veterinary Career
- Professor Argyle studied Veterinary Medicine at Glasgow University from 1986-1991, returning to undertake a doctorate (PhD) in Immunology and Oncology in following a period in general practice.
- He became senior lecturer in Clinical Gene Therapy and Oncology at Glasgow University in 1999.
- In 2002 he obtained a post as Associate Professor at the University of Wisconsin-Madison.[10]
- Argyle returned to Scotland in 2005 to become William Dick Chair of Veterinary Clinical Studies at the Dick Vet school in Edinburgh (part of the University of Edinburgh). There he set up the first Cancer and Imaging Centre for animals.[11]
- In 2009 Professor Argyle became Dean, International (Medicine and Veterinary Medicine) and Dean, Postgraduate Research (Medicine and Veterinary Medicine) at the University of Edinburgh.
- In 2011 he became Head of School, Royal (Dick) School of Veterinary Studies, University of Edinburgh.
- In 2016 he was elected a Fellow of the Royal Society of Edinburgh.[12]
- From 2017 to 2018 he served as Interim Head of the College of Medicine and Veterinary Medicine and VP for Medicine and Veterinary Medicine for the University of Edinburgh.
- He is joint Scientific Editor of the Journal of Veterinary and Comparative Oncology.[13]
- In June 2020 he was elected Junior Vice-President of the Royal College of Veterinary Surgeons for 2020-21. [14]
Controversy
In 2019 the Sunday Times published two articles alleging a 'toxic' culture at the Dick Vet school in Edinburgh, of which Argyle is Head. In 2020, an independent review (Intersol Global Report) was commissioned by the University of Edinburgh. The summary of the Intersol report was leaked to the national and veterinary press (Sunday Times[15] and The Veterinary Record [16] [17]), leading the RCVS to warn against 'Trial by media'. The allegations were rejected by an independent investigation, which concluded there was no evidence of misconduct. This conclusion was upheld after an appeal.[18]
Research
Professor Argyle’s research career began in the department of Veterinary Pathology (Glasgow) as a Wellcome PhD Fellowship under Professors David Onions and Neil Gorman. He was involved in isolating canine and feline cytokine genes, developing bioassays and taking these reagents towards clinical application, specifically in the development of vaccines for retroviral diseases and gene therapy tools.
Rooted in comparative biology, the majority of his career has involved studying the basic biology of cancer with the aim of identifying new diagnostic and therapeutic targets. This has included studies on the role of telomerase in cancer cell maintenance to, more recently, focusing on the understanding of the role of cancer stem cells in tumour initiation and metastatic disease.
His research in canine and feline cancers has established large animal models for human cancer studies such as the identification of biomarkers for breast cancer radio-resistance and the development of canine bone cancer as a model for human paediatric osteosarcoma. This work laid the foundation for a multidisciplinary programme developing implantable biosensors to monitor tumour microenvironment (IMPACT Implantable Microsystems for Anti-Cancer Therapy, an EPSRC programme involving Engineering, Medicine, Chemistry, Veterinary Medicine and Social Science), which successfully developed an in vivo sheep model for implantable devices in lung cancer.
Publications
Professor Argyle has over 150 peer-reviewed publications.
Books and Chapters
- Decision Making in Small Animal Oncology (2009)[19]
- Advances in cancer diagnostics (2008)[20]
- Decision making in feline cancer patients (2008)[21]
- What is new in canine and feline lymphoma (2008)[22]
- Preclinical Organotypic Models for the Assessment of Novel Cancer Therapeutics and Treatment (2019)[23]
References
- ^ "Prof David Argyle". The University of Edinburgh. Retrieved 2020-10-26.
- ^ "Professor David Argyle elected RCVS Junior Vice-President for 2020-21". Professionals. Retrieved 2020-10-26.
- ^ "Type - Professionals". www.rcvs.org.uk. Retrieved 2020-10-26.
- ^ Limited, BMJ Publishing Group (2012-12-22). "New head of clinical oncology for Edinburgh cancer centre". Veterinary Record. 171 (25): 636–636. doi:10.1136/vr.e8544. ISSN 0042-4900. PMID 23264376.
- ^ "Prof David Argyle - EBVS - European Board of Veterinary Specialists". ebvs.eu. Retrieved 2020-10-26.
- ^ Medicine, David Argyle | Dean of Veterinary; Edinburgh, Head of School University of (2020-10-26). "David Argyle | The Vet Expo". The Vet Expo 2020. Retrieved 2020-10-26.
- ^ "Prof David Argyle". The University of Edinburgh. Retrieved 2020-10-26.
- ^ "Head of School wins prestigious veterinary award". The University of Edinburgh. Retrieved 2020-10-26.
- ^ "Head of School wins prestigious veterinary award". The University of Edinburgh. Retrieved 2020-10-26.
- ^ "Prof David Argyle". The University of Edinburgh. Retrieved 24 May 2020.
- ^ "David Argyle - Edinburgh Research Explorer". www.research.ed.ac.uk.
- ^ "Professor David John Argyle FRSE". The Royal Society of Edinburgh. 24 March 2020. Retrieved 24 May 2020.
- ^ "Prof David Argyle – Roslin Technologies". Retrieved 24 May 2020.
- ^ "Professor David Argyle elected RCVS Junior Vice-President for 2020-21". The Royal College of Veterinary Surgeons. Retrieved 17 October 2020.
- ^ https://www.thetimes.co.uk/article/top-vet-professor-david-argyle-at-centre-of-bullying-claims-at-edinburgh-university-5hlnmwjl8
- ^ http://dx.doi.org/10.1136/vr.m3998
- ^ http://dx.doi.org/10.1136/vr.m3991
- ^ Frost, Sara (2020-10-23GMT06:00:07+00:00). "No trial by media for next college president – RCVS". Vet Times. Retrieved 2020-10-26.
{{cite web}}: Check date values in:|date=(help) - ^ "Decision Making in Small Animal Oncology David Argyle - Google Search". www.google.com. Retrieved 2020-10-26.
- ^ Argyle, D. J. (2008). "Advances in cancer diagnostics". Proceedings of the 33rd World Small Animal Veterinary Association Congress. Australian Small Animal Veterinary Association.
- ^ Argyle, D. J. (2008). "Decision making in feline cancer patients". Advances in cancer diagnostics.
- ^ Argyle, D. J. (2008). "What is new in canine and feline lymphoma". Advances in cancer diagnostics: 518–520.
- ^ Ward, Carol; Meehan, James; Gray, Mark; Kunkler, Ian; Langdon, Simon; Murray, Alan; Argyle, David (2019-03-12). "Preclinical Organotypic Models for the Assessment of Novel Cancer Therapeutics and Treatment". Current Topics in Microbiology and Immunology. doi:10.1007/82_2019_159.