ACYP1

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Acylphosphatase 1, erythrocyte (common) type
Protein ACYP1 PDB 2K7J.png
Rendering based on PDB 2K7J.
Available structures
PDB Ortholog search: PDBe, RCSB
Identifiers
Symbols ACYP1 ; ACYPE
External IDs OMIM600875 MGI1913454 HomoloGene11932 GeneCards: ACYP1 Gene
EC number 3.6.1.7
RNA expression pattern
PBB GE ACYP1 205260 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez 97 66204
Ensembl ENSG00000119640 ENSMUSG00000008822
UniProt P07311 P56376
RefSeq (mRNA) NM_001107 NM_025421
RefSeq (protein) NP_001098 NP_079697
Location (UCSC) Chr 14:
75.52 – 75.54 Mb
Chr 12:
85.27 – 85.29 Mb
PubMed search [1] [2]

Acylphosphatase-1 is an enzyme that in humans is encoded by the ACYP1 gene.[1][2][3]

Acylphosphatase is a small cytosolic enzyme that catalyzes the hydrolysis of the carboxyl-phosphate bond of acylphosphates. Two isoenzymes have been isolated, called muscle acylphosphatase and erythrocyte acylphosphatase, on the basis of their tissue localization. This gene encodes the erythrocyte acylphosphatase isoenzyme. Alternatively spliced transcript variants that encode different proteins were identified through data analysis.[3]

References[edit]

  1. ^ Fiaschi T, Raugei G, Marzocchini R, Chiarugi P, Cirri P, Ramponi G (Aug 1995). "Cloning and expression of the cDNA coding for the erythrocyte isoenzyme of human acylphosphatase". FEBS Lett 367 (2): 145–8. doi:10.1016/0014-5793(95)00553-L. PMID 7796909. 
  2. ^ Fiaschi T, Marzella R, Veggi D, Marzocchini R, Raugei G, Rocchi M, Ramponi G (Oct 1998). "Assignment of the human erythrocyte acylphosphatase gene (ACYP1) to chromosome band 14q24.3". Cytogenet Cell Genet 81 (3–4): 235–6. doi:10.1159/000015037. PMID 9730610. 
  3. ^ a b "Entrez Gene: ACYP1 acylphosphatase 1, erythrocyte (common) type". 

Further reading[edit]