ADM2
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| Adrenomedullin 2 | |||||||||||||
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| Identifiers | |||||||||||||
| Symbols | ADM2; AM2; dJ579N16.4 | ||||||||||||
| External IDs | OMIM: 608682 MGI: 2675256 HomoloGene: 49801 GeneCards: ADM2 Gene | ||||||||||||
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| RNA expression pattern | |||||||||||||
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| More reference expression data | |||||||||||||
| Orthologs | |||||||||||||
| Species | Human | Mouse | |||||||||||
| Entrez | 79924 | 223780 | |||||||||||
| Ensembl | ENSG00000128165 | ENSMUSG00000054136 | |||||||||||
| UniProt | Q7Z4H4 | Q7TNK8 | |||||||||||
| RefSeq (mRNA) | NM_001253845.1 | NM_182928.3 | |||||||||||
| RefSeq (protein) | NP_001240774.1 | NP_891558.1 | |||||||||||
| Location (UCSC) | Chr 22: 50.92 – 50.92 Mb |
Chr 15: 89.15 – 89.16 Mb |
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| PubMed search | [1] | [2] | |||||||||||
ADM2 is a protein that in humans is encoded by the ADM2 gene.[1][2]
ADM2 belongs to a family of calcitonin (MIM 114130)-related peptide hormones important for regulating diverse physiologic functions and the chemical composition of fluids and tissues.[supplied by OMIM][2]
[edit] References
- ^ Takei Y, Inoue K, Ogoshi M, Kawahara T, Bannai H, Miyano S (Jan 2004). "Identification of novel adrenomedullin in mammals: a potent cardiovascular and renal regulator". FEBS Lett 556 (1–3): 53–8. doi:10.1016/S0014-5793(03)01368-1. PMID 14706825.
- ^ a b "Entrez Gene: ADM2 adrenomedullin 2". http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=79924.
[edit] Further reading
- Kawai M (2004). "[Diagnosis of dermatophytoses: conventional methods and recent molecular biological methods]". Nihon Ishinkin Gakkai zasshi (Japanese journal of medical mycology) 44 (4): 261–4. PMID 14615790.
- Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22". Nature 402 (6761): 489–95. doi:10.1038/990031. PMID 10591208.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=139241.
- Roh J, Chang CL, Bhalla A, et al. (2004). "Intermedin is a calcitonin/calcitonin gene-related peptide family peptide acting through the calcitonin receptor-like receptor/receptor activity-modifying protein receptor complexes". J. Biol. Chem. 279 (8): 7264–74. doi:10.1074/jbc.M305332200. PMID 14615490.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Collins JE, Wright CL, Edwards CA, et al. (2005). "A genome annotation-driven approach to cloning the human ORFeome". Genome Biol. 5 (10): R84. doi:10.1186/gb-2004-5-10-r84. PMC 545604. PMID 15461802. http://www.pubmedcentral.nih.gov/articlerender.fcgi?tool=pmcentrez&artid=545604.
- Takahashi K, Kikuchi K, Maruyama Y, et al. (2006). "Immunocytochemical localization of adrenomedullin 2/intermedin-like immunoreactivity in human hypothalamus, heart and kidney". Peptides 27 (6): 1383–9. doi:10.1016/j.peptides.2005.11.004. PMID 16359754.
- Kindt F, Wiegand S, Löser C, et al. (2007). "Intermedin: a skin peptide that is downregulated in atopic dermatitis". J. Invest. Dermatol. 127 (3): 605–13. doi:10.1038/sj.jid.5700576. PMID 17008878.
- Morimoto R, Satoh F, Murakami O, et al. (2007). "Expression of adrenomedullin2/intermedin in human brain, heart, and kidney". Peptides 28 (5): 1095–103. doi:10.1016/j.peptides.2007.01.018. PMID 17346853.
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