Antsohimbondrona has a maritime harbour. Primary and junior level secondary education are available in town. The town provides access to hospital services to its citizens. It is also a site of industrial-scale mining.
The majority (65%) of the population are farmers. The most important crop is sugarcane, while other important products are cotton and rice. Industry and services provide employment for 13% and 7% of the population, respectively. Additionally fishing employs 15% of the population.